Patents Assigned to ADT Pharmaceuticals, LLC
  • Anticancer indenes, indanes, azaindenes, azaindanes, pharmaceutical compositions and uses
    Patent number: 11680073
    Abstract: Disclosed are compounds for medical uses, for example, compounds of formula Ia, wherein A1, A2, A3, A4, A5, A6, A7, R6, R7 and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: June 20, 2023
    Assignee: ADT PHARMACEUTICALS, LLC
    Inventors: Michael Boyd, Xi Chen
  • INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF
    Publication number: 20220315553
    Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Application
    Filed: June 8, 2022
    Publication date: October 6, 2022
    Applicant: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • Indenyl compounds, pharmaceutical compositions, and medical uses thereof
    Patent number: 11407727
    Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: August 9, 2022
    Assignee: ADT PHARMACEUTICALS, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • ANTICANCER INDENES, INDANES, AZAINDENES, AZAINDANES, PHARMACEUTICAL COMPOSITIONS AND USES
    Publication number: 20220048931
    Abstract: Disclosed are compounds for medical uses, for example, compounds of formula Ia, wherein A1, A2, A3, A4, A5, A6, A7, R6, R7 and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Application
    Filed: October 26, 2021
    Publication date: February 17, 2022
    Applicant: ADT PHARMACEUTICALS, LLC
    Inventors: Michael BOYD, Xi CHEN
  • Method of treating or preventing Ras-mediated diseases
    Patent number: 11198679
    Abstract: Disclosed are compounds, for example, a compound of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition for example, cancer, mediated by the ras gene.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: December 14, 2021
    Assignee: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • Anticancer indenes, indanes, azaindenes, azaindanes, pharmaceutical compositions and uses
    Patent number: 11186596
    Abstract: Disclosed are compounds for medical uses, for example, compounds of formula (Ia), wherein A1, A2, A3, A4, A5, A6, A7, R6, R7 and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: November 30, 2021
    Assignee: ADT Pharmaceuticals, LLC
    Inventors: Michael Boyd, Xi Chen
  • Indenyl compounds, pharmaceutical compositions, and medical uses thereof
    Patent number: 11130744
    Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: September 28, 2021
    Assignee: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • Method of treating or preventing Ras-mediated diseases
    Patent number: 11104658
    Abstract: Disclosed are compounds, for example, a compound of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition for example, cancer, mediated by the ras gene.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: August 31, 2021
    Assignee: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • ANTICANCER INDENES, INDANES, AZAINDENES, AZAINDANES, PHARMACEUTICAL COMPOSITIONS AND USES
    Publication number: 20210261572
    Abstract: Disclosed are compounds for medical uses, for example, compounds of formula (Ia), wherein A1, A2, A3, A4, A5, A6, A7, R6, R7 and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Application
    Filed: April 26, 2019
    Publication date: August 26, 2021
    Applicant: ADT PHARMACEUTICALS, LLC
    Inventors: Michael BOYD, Xi CHEN
  • Indenyl compounds, pharmaceutical compositions, and medical uses thereof
    Patent number: 10981886
    Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: April 20, 2021
    Assignee: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • Indenyl compounds, pharmaceutical compositions, and medical uses thereof
    Patent number: 10975054
    Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: April 13, 2021
    Assignee: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF
    Publication number: 20200223816
    Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Application
    Filed: March 30, 2020
    Publication date: July 16, 2020
    Applicant: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • METHOD OF TREATING OR PREVENTING RAS-MEDIATED DISEASES
    Publication number: 20200223817
    Abstract: Disclosed are compounds, for example, a compound of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition for example, cancer, mediated by the ras gene.
    Type: Application
    Filed: April 1, 2020
    Publication date: July 16, 2020
    Applicant: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF
    Publication number: 20200223815
    Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Application
    Filed: March 30, 2020
    Publication date: July 16, 2020
    Applicant: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF
    Publication number: 20200048217
    Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Application
    Filed: October 4, 2019
    Publication date: February 13, 2020
    Applicant: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF
    Publication number: 20200031795
    Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 30, 2020
    Applicant: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd
  • Indenyl compounds, pharmaceutical compositions, and medical uses thereof
    Patent number: 10526307
    Abstract: Disclosed are compounds, for example, compounds of formula (I), (Formula (I) wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: January 7, 2020
    Assignee: ADT Pharmaceuticals, LLC
    Inventors: Gary A. Piazza, Xi Chen, Adam B. Keeton, Michael R. Boyd