Abstract: A socket is described for use with a partial prosthesis of the hand. The socket includes a base layer molded to encapsulate and conform to the contours of a natural hand. The base layer has a dorsal portion and a palmar portion. The palmar portion has a distal edge positioned, in use, proximal to the transverse metacarpal arch of a natural hand, and the dorsal portion having a distal edge positioned, in use, along a transverse span along a mid-portion of the dorsum of the natural hand in an area proximal to the area of the second through fifth metacarpals of a natural hand. The palmar portion of the base layer defines a first open area around the hypo-thenar eminence and a second open area surrounding on the palmar portion the thenar eminence and extending to the radial side of the second metacarpal on the dorsal portion.