Patents Assigned to Advanced Biotherapy, Inc.
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Patent number: 7462454Abstract: The present invention includes methods for the treatment of a herpes simplex virus infection comprising the administration of inhibitors of gamma interferon, tumor necrosis alpha and interleukin-1.Type: GrantFiled: October 7, 2005Date of Patent: December 9, 2008Assignee: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Patent number: 7232568Abstract: The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination with other drugs are described. Also disclosed in the invention are methods of applying a composition comprising interferon gamma antibodies topically to the eye to treat hyperimmune reactions, such as transplant rejection, autoimmune diseases of the eye, and ocular disorders incidental to or connected with autoimmune diseases.Type: GrantFiled: February 21, 2003Date of Patent: June 19, 2007Assignee: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Patent number: 7115263Abstract: The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination with other drugs are described. Also disclosed in the invention are methods of applying a composition comprising interferon gamma antibodies topically to the eye to treat hyperimmune reactions, such as transplant rejection, uveitis, autoimmune diseases of the eye, and ocular disorders incidental to or connected with autoimmune diseases.Type: GrantFiled: February 28, 2005Date of Patent: October 3, 2006Assignee: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Patent number: 6863890Abstract: The present disclosure concerns the treatment of a patient with autoimmune disease, including AIDS, by neutralizing, removing or inhibiting different types of interferons, tumor necrosis factor, HLA class II antigens, IgE, and other pathological factors and/or their receptors, as well as neutralizing, removing or inhibiting autoantibodies, including antibodies to target cells, CD4 cells and DNA. Treatment comprises administration of an autoimmune inhibitor, or extracorporeal exposure of the patient's fluid to an immunosorbent comprising an autoimmune inhibitor, followed by return of the treated fluid to the patient; or it comprises a combined therapy involving extracorporeal immunosorption in conjunction with the administration of an autoimmune inhibitor.Type: GrantFiled: January 20, 2000Date of Patent: March 8, 2005Assignee: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon V. Skurkovich
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Patent number: 6861056Abstract: The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination with other drugs are described. Also disclosed in the invention are methods of applying a composition comprising interferon gamma antibodies topically to the eye to treat hyperimmune reactions, such as transplant rejection, uveitis, autoimmune diseases of the eye, and ocular disorders incidental to or connected with autoimmune diseases.Type: GrantFiled: March 14, 2003Date of Patent: March 1, 2005Assignee: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Publication number: 20040136988Abstract: The invention includes methods of treating schizophrenia in a patient where the method includes administration of antibodies to TNF-alpha and interferon-gamma to the patient. The invention further includes methods of treating schizophrenia in a patient where the method comprises administration of an antibody to TNF-alpha.Type: ApplicationFiled: June 25, 2003Publication date: July 15, 2004Applicant: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Publication number: 20040086508Abstract: The present invention comprises and utilizes methods and compositions for treating organ and cell transplant rejection. Compositions comprising antibodies to gamma interferon and tumor necrosis factor alone, together, and in combination with other drugs are described. Further disclosed are methods of treating organ transplant rejection comprising the administration of antibodies to cytokine receptors, soluble receptors, and extracorporeal removal of cytokines and other autoimmune mediators.Type: ApplicationFiled: July 30, 2003Publication date: May 6, 2004Applicant: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Publication number: 20040062768Abstract: The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination with antibodies to TNF alpha and other drugs are described. Also disclosed in the invention are methods of applying a composition comprising interferon gamma antibodies and TNF alpha antibodies, alone and in combination, topically to the eye to treat hyperimmune reactions, such as transplant rejection, autoimmune diseases of the eye, and ocular disorders incidental to or connected with autoimmune diseases.Type: ApplicationFiled: August 5, 2003Publication date: April 1, 2004Applicant: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Publication number: 20040052792Abstract: The invention includes methods of treating schizophrenia in a patient where the method includes administration of antibodies to TNF-alpha and interferon-gamma to the patient. The invention further includes methods of treating schizophrenia in a patient where the method comprises administration of an antibody to TNF-alpha.Type: ApplicationFiled: June 25, 2003Publication date: March 18, 2004Applicant: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Publication number: 20040052790Abstract: The invention includes methods of treating schizophrenia in a patient where the method includes administration of antibodies to TNF-alpha and interferon-gamma to the patient. The invention further includes methods of treating schizophrenia in a patient where the method comprises administration of an antibody to TNF-alpha.Type: ApplicationFiled: April 24, 2003Publication date: March 18, 2004Applicant: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Publication number: 20030228310Abstract: The invention includes methods of treating skin-related autoimmune disease in a patient, where the method includes administration of an antibody to interferon-gamma, interleukin-1, and tumor necrosis factor alpha to a patient.Type: ApplicationFiled: November 26, 2002Publication date: December 11, 2003Applicant: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Publication number: 20030224005Abstract: The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination with other drugs are described. Also disclosed in the invention are methods of applying a composition comprising interferon gamma antibodies topically to the eye to treat hyperimmune reactions, such as transplant rejection, autoimmune diseases of the eye, and ocular disorders incidental to or connected with autoimmune diseases.Type: ApplicationFiled: February 21, 2003Publication date: December 4, 2003Applicant: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Publication number: 20030223995Abstract: The invention includes methods of treating skin-related autoimmune disease in a patient where the method includes administration of antibody to gamma interferon to the patient.Type: ApplicationFiled: November 26, 2002Publication date: December 4, 2003Applicant: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Publication number: 20030215448Abstract: The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination with other drugs are described. Also disclosed in the invention are methods of applying a composition comprising interferon gamma antibodies topically to the eye to treat hyperimmune reactions, such as transplant rejection, uveitis, autoimmune diseases of the eye, and ocular disorders incidental to or connected with autoimmune diseases.Type: ApplicationFiled: March 14, 2003Publication date: November 20, 2003Applicant: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Publication number: 20030086925Abstract: The invention includes methods of treating skin-related autoimmune disease in a patient, graft-versus-host disease, and bone marrow transplant rejection, where the method includes administration of antibody to gamma interferon to the patient.Type: ApplicationFiled: July 3, 2002Publication date: May 8, 2003Applicant: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Patent number: 6534059Abstract: The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination with other drugs are described. Also disclosed in the invention are methods of applying a composition comprising interferon gamma antibodies topically to the eye to treat hyperimmune reactions, such as transplant rejection, autoimmune diseases of the eye, and ocular disorders incidental to or connected with autoimmune diseases.Type: GrantFiled: June 28, 2001Date of Patent: March 18, 2003Assignee: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich
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Publication number: 20020182212Abstract: The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination with other drugs are described. Also disclosed in the invention are methods of applying a composition comprising interferon gamma antibodies topically to the eye to treat hyperimmune reactions, such as transplant rejection, autoimmune diseases of the eye, and ocular disorders incidental to or connected with autoimmune diseases.Type: ApplicationFiled: June 28, 2001Publication date: December 5, 2002Applicant: Advanced Biotherapy, Inc.Inventors: Boris Skurkovich, Simon Skurkovich