Abstract: Systems and methods for assessing compliance with position therapy. In an embodiment, position therapy is provided to a user while the user is wearing a position therapy device. The position therapy comprises, by the device, collecting positional data, determining positions of the user over a time period based on the positional data, and, when it is determined that the user is in a target position, providing feedback to the user to influence the user to change to a non-target position. In addition, the device stores a duration of use in its memory. The duration of use indicates a duration that the user has used the wearable position therapy device in each of one or more positions. An assessment of the user's compliance with the position therapy is then provided based, at least in part, on the duration of use.

Abstract: Systems and methods for assessing compliance with position therapy. In an embodiment, position therapy is provided to a user while the user is wearing a position therapy device. The position therapy comprises, by the device, collecting positional data, determining positions of the user over a time period based on the positional data, and, when it is determined that the user is in a target position, providing feedback to the user to influence the user to change to a non-target position. In addition, the device stores a duration of use in its memory. The duration of use indicates a duration that the user has used the wearable position therapy device in each of one or more positions. An assessment of the user's compliance with the position therapy is then provided based, at least in part, on the duration of use.

Abstract: A wearable positional therapy device for influencing a position of a user. In an embodiment, the device comprises a position detector that generates positional data used to determine a position of a user, a feedback generator that generates feedback to the user, and a microcontroller. The microcontroller is configured to receive and analyze the positional data to determine whether the user is in a target position, while, in response to the device being turned on or a reset operation, delaying feedback for a delay period. If it is determined that the user is in the target position during the delay period, no feedback is provided. However, if it is determined that the user is in the target position following the delay period, feedback is provided to the user to induce the user to change to a different, non-target position.

Abstract: Sleep mask for reducing sleep inertia. In an embodiment, the sleep mask comprises a foam layer having a shape that covers both of a human subject's eyes so as to attenuate ambient light. Visual stimulation element(s), configured to emit light, are positioned between the foam layer and the subject's eyes. In addition, a plurality of sensors positioned on the forehead of the subject collect electroencephalogram (EEG), electrooculogram (EOG), and electromyogram (EMG) signals. A soft exterior cover houses the foam layer, the visual stimulation element(s), and the sensors. The sleep mask further comprises processor(s) that determine and record each sleep stage of the subject, determine when to wake the subject, and, when it is determined to wake the subject, control the visual stimulation element(s) to wake the subject using emitted light.

Abstract: Systems and methods for controlling the position of a user of a wearable positional therapy device are provided. The wearable position therapy device can be configured to monitor and store physiological signals that can be used to assess sleep quality and sleeping position of a user. The device can be configured to be worn around the head, the neck, or body of the user. The device can be configured to provide feedback to a user if the user is sleeping or is positioned in a target position to induce the user to change positions. The feedback can be provided by one or more haptic motors that can be configured to provide various levels of feedback and the level of feedback can be customized based on the user's reaction to the feedback.

Abstract: Systems and methods for optimizing sleep and post-sleep performance. In an embodiment, a system comprising a device and sleep mask are provided. The mask may comprise electroencephalographic (EEG) sensors and one or more stimulation elements configured to stimulate the senses of a wearer of the mask. The mask may be releasably and electrically coupled to a device which receives EEG signals from the mask, determines current and target sleep states based, at least in part, on the EEG signals, and uses this determination to tailor a sleep architecture of the wearer by controlling the stimulation elements. The mask may be a soft mask which utilizes conductive thread embroidered into one or more textile layers. In an embodiment, the stimulation elements may comprise one or more heating elements, electroluminescent panels, and speakers. In addition, the EEG sensors may comprise hybrid sensors comprising hydrogel in a conductive spacer fabric.

Abstract: Systems and methods are provided for optimizing the treatment of obstructive sleep apnea (OSA) using an oral appliance. The oral appliance can be configured by non-dental staff to safely conform to the dentition of a patient. The appliance includes configurable trays that include retention material that conforms to the dentition of the patient. The position of the upper and lower trays relative to one another can be adjusted both horizontally and vertically. The position of the upper and lower trays can be locked into place to maintain the position of the trays at a preferred treatment position. Methods for creating an appliance customized for a patient are also provided. Methods for using the customized appliance in combination with sleep study data is also provide. Methods for using the customized appliance to with pre-operative assessments and sleep study data to predict and reduce the risk of perioperative complications are also provided.

Abstract: Systems and methods for assessment of sleep quality in adults and children are provided. These techniques include an apparatus worn above the forehead containing the circuitry for collecting and storing physiological signals. The apparatus integrates with a sensor strip and a nasal mask to obtain the physiological signals for the user. The form factor of this apparatus is comfortable, easy to self-apply, and results in less data artifacts than conventional techniques for capturing physiological data for analyzing sleep quality. Neuro-respiratory signals are analyzed using means to extract more accurate definitions of the frequency and severity of sleep discontinuity, sleep disordered breathing and patterns of sleep architecture. Biological biomarkers and questionnaire responses can also be compared to a database of healthy and chronically diseased patients to provide a more accurate differential diagnosis and to help determine the appropriate disease management recommendations.

Abstract: Systems and methods for optimizing the sleep and post-sleep performance of individuals regardless of their environment and time available for sleep are provided. The systems and methods take into account factors that determine the effects of a sleep episode on dexterity, cognitive functions and the subjective feeling of fatigue after sleeping: duration and sleep architecture of the sleep episode, point on the circadian cycle at which the episode occurred, the amount of sleep debt accumulated prior to the episode and the subject's susceptibility to sleep deprivation. The systems and methods include monitoring of sleep architecture over a longer period of time, measurement of accumulated sleep debt and assessment and/or tailoring of the sleep architecture for each subsequent sleep episode, determining a desired sleep state in which the subject should be in, and generating sensory stimuli for guiding the subject to the desired sleep state.

Abstract: Systems and methods for assessment of sleep quality in adults and children are provided. These techniques include an apparatus worn above the forehead containing the circuitry for collecting and storing physiological signals. The apparatus integrates with a sensor strip and a nasal mask to obtain the physiological signals for the user. The form factor of this apparatus is comfortable, easy to self-apply, and results in less data artifacts than conventional techniques for capturing physiological data for analyzing sleep quality. Neuro-respiratory signals are analyzed using means to extract more accurate definitions of the frequency and severity of sleep discontinuity, sleep disordered breathing and patterns of sleep architecture. Biological biomarkers and questionnaire responses can also be compared to a database of healthy and chronically diseased patients to provide a more accurate differential diagnosis and to help determine the appropriate disease management recommendations.

Abstract: A method and apparatus for assessment of hemodynamic and functional state of the brain is disclosed. In one embodiment, the method and apparatus includes non-invasive measurement of intracranial pressure, assessment of the brain's electrical activity, and measurement of cerebral blood flow. In some embodiments, the method and apparatus include measuring the volume change in the intracranial vessels with a near-infrared spectroscopy or other optical method, measuring the volume change in the intracranial vessels with rheoencephalography or other electrical method, and measuring the brain's electrical activity using electroencephalography.

Abstract: Systems and methods are provided for optimizing the treatment of obstructive sleep apnea (OSA) using an oral appliance. The oral appliance can be configured by non-dental staff to safely conform to the dentition of a patient. The appliance includes configurable trays that include retention material that conforms to the dentition of the patient. The position of the upper and lower trays relative to one another can be adjusted both horizontally and vertically. The position of the upper and lower trays can be locked into place to maintain the position of the trays at a preferred treatment position. Methods for creating an appliance customized for a patient are also provided. Methods for using the customized appliance in combination with sleep study data is also provide. Methods for using the customized appliance to with pre-operative assessments and sleep study data to predict and reduce the risk of perioperative complications are also provided.

Abstract: Photoplethysmography (PPG) is obtained using one red (e.g., 660 nm) and one infrared (e.g., 880 to 940 nm) light emitting diode with a single photo diode in combination with a pressure transducer thereby allowing both CVP and SpO2 to be measured simultaneously. The system also includes sensors capable of measuring position, angle and/or movement of the sensor or patient. Once the PPG signal is acquired, high pass adaptive and/or notch filtering can be used with one element of the filter from the red and infrared signals used to measure the arterial changes needed to compute SpO2 and the other element of the signal can be used to measure CVP changes.

Abstract: The EEG electrode and EEG electrode locator assembly may be used in combination with an EEG electrode locator headgear including a plurality of locator straps connectable to one or more of the EEG electrode locators that form an electrode locator assembly with the EEG electrode, for accurately positioning one or more of the EEG electrodes relative to the user's scalp, and for biasing the plurality of electrodes toward the user's scalp. The EEG electrode is adapted to be received in and cooperate with an EEG electrode locator ring, to form the electrode locator assembly. The EEG electrode includes a dispenser assembly adapted to dispense an electrically conductive gel onto the user's scalp to prepare the user's scalp.

Abstract: The method for the quantification of EEG waveforms along the alertness continuum involves collecting and transforming EEG signal data, identifying and rejecting or decontaminating epochs containing various artifacts, and classifying individual EEG patterns along an alertness-drowsiness continuum. The results of the multi-level classification system are applied in real-time to provide feedback to the user via an audio or visual alarm, or are recorded for subsequent off-line analysis.

Abstract: The method for the quantification of EEG waveforms along the alertness continuum involves collecting and transforming EEG signal data, identifying and rejecting or decontaminating epochs containing various artifacts, and classifying individual EEG patterns along an alertness-drowsiness continuum. The results of the multi-level classification system are applied in real-time to provide feedback to the user via an audio or visual alarm, or are recorded for subsequent off-line analysis.

Abstract: The EEG electrode locator headgear allows the user to locate and apply disposable EEG electrodes accurately according to the International 10/20 System without technical assistance, to allow the acquisition of high quality EEG signals. The headgear includes a front forehead pad, a base strap assembly connected to the front forehead pad, a plurality of EEG electrode locators for receiving EEG electrodes, and a plurality of locator straps connected to the front pad of material, the base strap assembly, and to the plurality of EEG electrode locators for accurately positioning the plurality of EEG electrode locators positioned relative to the scalp of a user. A visor can be attached to the front pad of material, and the base strap assembly may include an occipital locator device. A plunger assembly with spreadable fingers for optionally parting the hair of the user's scalp is also provided that is inserted in the electrode locators to optionally prepare the user's scalp and to seat the electrodes.

Abstract: The EEG electrode locator headgear allows the user to locate and apply disposable EEG electrodes accurately according to the International 10/20 System without technical assistance, to allow the acquisition of high quality EEG signals. The headgear includes a front forehead pad, a base strap assembly connected to the front forehead pad, a plurality of EEG electrode locators for receiving EEG electrodes, and a plurality of locator straps connected to the front pad of material, the base strap assembly, and to the plurality of EEG electrode locators for accurately positioning the plurality of EEG electrode locators positioned relative to the scalp of a user. A visor can be attached to the front pad of material, and the base strap assembly may include an occipital locator device. A plunger assembly with spreadable fingers for parting the hair of the scalp of the user is also provided that is inserted in the electrode locators to prepare the scalp of the user and to seat the electrodes.