Abstract: According to some embodiments, a medical instrument comprises an elongate body having a proximal end and a distal end and a pair of electrodes or electrode portions (for example, a split-tip electrode assembly). Systems and methods are described herein that perform contact sensing and/or ablation confirmation based on electrical measurements obtained while energy of different frequencies are applied to the pair of electrodes or electrode portions. The contact sensing systems and methods may calibrate network parameter measurements to compensate for a hardware unit in a network parameter measurement circuit or to account for differences in cables, instrumentation or hardware used.

Abstract: According to some embodiments, a medical instrument (for example, an ablation device) comprises an elongate body having a proximal end and a distal end, an energy delivery member positioned at the distal end of the elongate body, a first plurality of temperature-measurement devices carried by or positioned within the energy delivery member, the first plurality of temperature-measurement devices being thermally insulated from the energy delivery member, and a second plurality of temperature-measurement devices positioned proximal to a proximal end of the energy delivery member, the second plurality of temperature-measurement devices being thermally insulated from the energy delivery member.

Abstract: According to some embodiments, an ablation device comprises an elongate body (e.g., a catheter) having a proximal end and a distal end, a first electrode (e.g., a radiofrequency electrode) positioned at the distal end of the elongate body, at least a second electrode (e.g., a radiofrequency electrode) positioned at a location proximal to the first electrode, the first electrode and the second electrode being configured to contact tissue of a subject and deliver radiofrequency energy sufficient to at least partially ablate the tissue, at least one electrically insulating gap positioned between the first electrode and the second electrode and a filtering element configured to present a low impedance at a frequency used for delivering ablation energy via the first and second electrodes.

Abstract: According to some embodiments, a medical instrument (for example, an ablation device) comprises an elongate body having a proximal end and a distal end, an energy delivery member positioned at the distal end of the elongate body, a first plurality of temperature-measurement devices carried by or positioned within the energy delivery member, the first plurality of temperature-measurement devices being thermally insulated from the energy delivery member, and a second plurality of temperature-measurement devices positioned proximal to a proximal end of the energy delivery member, the second plurality of temperature-measurement devices being thermally insulated from the energy delivery member.

Abstract: According to some embodiments, a medical instrument (for example, an ablation device) comprises an elongate body having a proximal end and a distal end, an energy delivery member positioned at the distal end of the elongate body, a first plurality of temperature-measurement devices carried by or positioned within the energy delivery member, the first plurality of temperature-measurement devices being thermally insulated from the energy delivery member, and a second plurality of temperature-measurement devices positioned proximal to a proximal end of the energy delivery member, the second plurality of temperature-measurement devices being thermally insulated from the energy delivery member.

Abstract: According to some embodiments, methods and systems of enhancing a map of a targeted anatomical region comprise receiving mapping data from a plurality of mapping electrodes, receiving high-resolution mapping data from a high-resolution roving electrode configured to be moved to locations between the plurality of mapping electrodes, wherein the mapping system is configured to supplement, enhance or refine a map of the targeted anatomical region or to directly create a high-resolution three-dimensional map using the processor receiving the data obtained from the plurality of mapping electrodes and from the high-resolution roving electrode.

Abstract: According to some embodiments, an ablation system or other treatment system comprises an elongate body, a first energy delivery member positioned along the distal end of the elongate body, and at least a second energy delivery member positioned at a location proximal to the first energy delivery member, the first energy delivery member and the second energy delivery member being configured to deliver energy sufficient to at least partially ablate tissue. In some embodiments, each of the first and second energy delivery members comprises an antenna configured to receive a microwave signal corresponding to a temperature of the tissue at a location adjacent the antenna. The system further comprises at least one radiometer configured to process the microwave signals received from the antennas of the energy delivery members and configured to produce an output signal representative of tissue temperatures at depth adjacent the first and second energy delivery members.

Abstract: According to some embodiments, systems for energy delivery to targeted tissue comprise a catheter with an ablation member, a radiometer configured to detect temperature data from the targeted tissue, a processor configured to determine a calculated temperature (e.g., an extreme temperature, such as a peak or trough temperature) within the tissue by applying at least one factor to the temperature data detected by the radiometer, the processor configured to compare the calculated temperature to a setpoint and an energy source configured to energize the ablation member and to regulate delivery of ablative energy to the targeted tissue of the subject based at least in part on the comparison. In some embodiments, the factor depends on at least one characteristic of the targeted tissue. Information regarding a tissue characteristic can be provided using information from an imaging set (e.g., intracardiac echo) or an electrical signal of the subject (e.g., electrocardiogram).

Abstract: The present invention provides systems and methods for radiometrically measuring temperature and detecting tissue contact during ablation. An interface module includes a first input/output (I/O) port for receiving radiometer and thermocouple signals from an integrated catheter tip (ICT) that includes a radiometer; a second I/O port for receiving ablative energy from an electrosurgical generator; a temperature display; a patient relay; a computer-readable medium storing radiometer and thermocouple parameters and instructions for causing the processor to: calculate a temperature adjacent to the ICT based on the radiometer and thermocouple signals and the parameters; causing the temperature display to display the calculated temperature; closing the patient relay to pass ablative energy from the second to the first I/O port; determining whether the ICT is in contact with tissue based on the radiometer signal. An output device indicates whether the ICT is determined to be in contact with the tissue.

Abstract: The present invention provides systems and methods for temperature-controlled ablation using radiometric feedback. An interface module may include (a) a processor; (b) a first input/output (I/O) port to receive digital radiometer and digital thermocouple signals from an integrated catheter tip (ICT); (c) a second I/O port to receive ablative energy from a generator; (d) a temperature display; (e) a patient relay; (f) a computer-readable medium storing instructions for causing the processor to: (i) calculate a temperature adjacent to the ICT based on the digital radiometer and thermocouple signals and operation parameters; (ii) cause the temperature display to display the calculated temperature; and (iii) close the patient relay to pass ablative energy received on the second I/O port to the first I/O port; and (g) a temperature control subsystem to regulate the ablative power based on the calculated temperature.

Abstract: Methods and systems are provided for detecting tissue contact prior to and/or during energy delivery to tissue. For example, the methods may include calculating temperature and detecting tissue contact based on signal(s) received from a radiometer. The radiometer may provide information about whether a treatment device is in contact with the tissue, and thus provide feedback to assist a clinician in properly contacting and treating the tissue.

Abstract: According to some embodiments, systems for energy delivery to targeted tissue comprise a catheter with an ablation member, a radiometer configured to detect temperature data from the targeted tissue, a processor configured to determine a calculated temperature (e.g., an extreme temperature, such as a peak or trough temperature) within the tissue by applying at least one factor to the temperature data detected by the radiometer, the processor configured to compare the calculated temperature to a setpoint and an energy source configured to energize the ablation member and to regulate delivery of ablative energy to the targeted tissue of the subject based at least in part on the comparison. In some embodiments, the factor depends on at least one characteristic of the targeted tissue. Information regarding a tissue characteristic can be provided using information from an imaging set (e.g., intracardiac echo) or an electrical signal of the subject (e.g., electrocardiogram).

Abstract: Methods and systems for treating tissue that employ a radiometer for temperature measurements and use feedback from the radiometer to regulate energy being applied to the tissue are provided. For example, methods and systems are provided for calculating temperature based on signal(s) from a radiometer, which may provide useful information about tissue temperature at depth, and automatically regulating energy applied to the tissue based on the tissue temperature.

Abstract: The present invention provides systems and methods for radiometrically measuring temperature and detecting tissue contact during ablation. An interface module includes a first input/output (I/O) port for receiving radiometer and thermocouple signals from an integrated catheter tip (ICT) that includes a radiometer; a second I/O port for receiving ablative energy from an electrosurgical generator; a temperature display; a patient relay; a computer-readable medium storing radiometer and thermocouple parameters and instructions for causing the processor to: calculate a temperature adjacent to the ICT based on the radiometer and thermocouple signals and the parameters; causing the temperature display to display the calculated temperature; closing the patient relay to pass ablative energy from the second to the first I/O port; determining whether the ICT is in contact with tissue based on the radiometer signal. An output device indicates whether the ICT is determined to be in contact with the tissue.

Abstract: Methods and systems for treating tissue that employ a radiometer for measurement and/or control are provided. For example, methods and systems are provided for radiometrically measuring temperature, such as by calculating temperature based on signal(s) from a radiometer, thereby providing useful information about tissue temperature at depth, even during an optional irrigated procedure.

Abstract: The present invention provides systems and methods for radiometrically measuring temperature during ablation. An interface module includes a processor; a first input/output (I/O) port configured to receive digital radiometer and thermocouple signals from an integrated catheter tip (ICT) that includes a radiometer; a second I/O port configured to receive ablative energy from an electrosurgical generator; a temperature display; a patient relay in communication with the first and second I/O ports and the processor; and a computer-readable medium storing radiometer and thermocouple operation parameters and instructions for causing the processor to: calculate a temperature adjacent to the ICT based on the radiometer and thermocouple signals and the operation parameters, causing the temperature display to display the calculated temperature, and closing the patient relay so as to pass ablative energy received on the second I/O port to the first I/O port.

Abstract: Methods and systems for treating tissue that employ a radiometer for measurement and/or control are provided. For example, methods and systems are provided for radiometrically measuring temperature, such as by calculating temperature based on signal(s) from a radiometer, thereby providing useful information about tissue temperature at depth, even during an optional irrigated procedure.

Abstract: Methods and systems for treating tissue that employ a radiometer for temperature measurements and use feedback from the radiometer to regulate energy being applied to the tissue are provided. For example, methods and systems are provided for calculating temperature based on signal(s) from a radiometer, which may provide useful information about tissue temperature at depth, and automatically regulating energy applied to the tissue based on the tissue temperature.