Abstract: Antimicrobial or preservative compositions with high user comfort and/or low ocular irritation. The compositions comprise a polyquaternary ammonium compound and an amidoamine having an alcohol group and exhibit synergistic antimicrobial activity. The compositions may be used as stand-alone antimicrobials/preservatives or may be incorporated into other ocular compositions such as those for ocular lens care or the treatment of ocular conditions.

Abstract: An ophthalmic lens for providing enhanced or extended depth of focus includes an optic having an aperture disposed about an optical axis. The optic includes a first surface having a first shape and an opposing second surface having a second shape, the first and second surfaces providing, a base power and, in some embodiments an add power. The optic further includes an extended focus mask disposed upon at least one of the first shape and the second shape that is configured to provide the enhanced or extended depth of focus for one or more foci of the optic, as compared to a similar optic not having the extended focus mask.

Abstract: An intraocular lens for correcting or reducing the astigmatism of a cornea includes a pupil that is spatially divided into discrete zones, with each zone having a particular astigmatism magnitude and astigmatism orientation. In one embodiment, the zones all have the same astigmatism magnitude, which is equal and opposite the cornea astigmatism magnitude to within a particular tolerance, such as 0.25 diopters. In one embodiment, some or all of the zones all have different astigmatism orientations, with the angular separation between astigmatism orientations being on the order of the rotational misalignment tolerance of the lens to the cornea. The visual performance of such a lens deteriorates more slowly with rotational misalignment, when compared to a comparable lens having a uniform astigmatism orientation across its entire pupil, leading to more relaxed tolerances for a surgeon that implants the lens.

Abstract: A multi-purpose contact lens care solution having high antimicrobial activity comprising, in an aqueous liquid medium, cetylpyridinium chloride and a non-ionic surfactant. In one embodiment of the invention, the non-ionic surfactant is a poly(oxypropylene)-poly(oxyethylene) block copolymer. The solution may optionally also include additional antimicrobial components, a buffer component, a viscosity inducing component, a surfactant, taurine, propylene glycol and/or a tonicity component. This solution additionally prevents losses in ocular tissue membrane integrity during contact lens wear.

Abstract: The field of the invention relates to medical packaging and, more particularly, to trays for holding sterile surgical components. In one embodiment, an ergonomic disposable tray is provided which can rest easily in the palm of the hand and be easily grasped. Moreover, the tray includes the addition of a raised triangular protrusion in all four opposing corners, to make opening the tray equally efficient for both right and left handed users. These features will allow the user to maintain control of the tray while peeling back the lid, keeping the internal components sterile.

Abstract: An ophthalmic lens for providing a plurality of foci has an optic including an anterior surface, a posterior surface, and an optical axis. The ophthalmic lens further includes a central phase plate, an intermediate phase plate surrounding the central phase plate, and an outer refractive region. The central phase plate comprises a first base curvature having a first radius of curvature and is configured such that the lens is able to direct light to a first focus and a second focus corresponding different diffraction orders of the phase plate. The intermediate phase plate is configured to change the overall resultant distribution of light directed to the second focus. The outer refractive region has no diffractive optical power and surrounds the intermediate phase plate. The outer refractive region is configured to direct light to the second focus and has an aspheric shape configured to reduce an optical aberration.

Abstract: A method and system for superimposing a ruler on a visual representation of a surgical procedure is presented. The design includes providing a reference object while recording the visual representation of the surgical procedure, scaling the ruler to correspond to the reference object within the visual representation of the surgical procedure, and superimposing the ruler from the scaling on the visual representation for subsequent viewing.

Abstract: An intraocular lens is disclosed, which includes a diffractive element with a relatively low add power. The add power may be less than about 2 Diopters, may be less than about 1 Diopter, or may be in the ranges of 0.5 to 2.5 Diopters, or 1.0 to 2.0 Diopters, or 1.5 to 2.0 Diopters, or 1.0 to 1.5 Diopters. The low-add-power diffractive element increases the depth of the focus of the intraocular lens, for example, compared to a similarly shaped intraocular lens without the diffractive element. In one embodiment, the depth of focus is defined in terms of a threshold MTF value at a particular spatial frequency. The threshold may be an absolute threshold, such as 0.10, 0.15, 0.17, 0.20, 0.25 or 0.30, or may be a relative threshold, such as a particular percentage of the peak value. The spatial frequency may be 25 line pairs per mm, 50 line pairs per mm, 100 line pairs per mm, or any suitable value.

Abstract: System and method of photoaltering a region of a material using a pulsed laser beam. The method includes scanning the pulsed laser beam in a first portion of the region with a first pattern, scanning the pulsed laser beam in a second portion of the region with a second pattern, and separating a flap of the material at the region. The system includes a laser, a controller selecting at least first and second patterns, and a scanner operable in response to the controller. The first pattern has a first maximum acceleration associated with the second portion, and the second pattern has a second maximum acceleration associated with the second portion. The second maximum acceleration is less than the first maximum acceleration. The scanner scans the pulsed laser beam from the laser in the first portion with the first pattern and in the second portion with the second pattern.

Abstract: A polymeric material with a variable modulus of elasticity is described herein. The polymeric material described herein is useful for forming implantable medical devices (e.g. ophthalmic lenses, breast implants, and body augmentation devices). In addition, medical devices formed from the polymer material can be used to controllably release a therapeutic agent. Also, the polymeric material may be used to prepare topical compositions or other applications or devices where control of a mechanical property such as material modulus is important.

Abstract: A system for determining the shape of an object and/or a distance of the object from the system includes a first plurality of light source, a second plurality of light sources, and a detector or detector array. The first plurality of light sources are disposed about a central axis and are separated from the central axis by radial distances defining an aperture in the first plurality of light sources. The system also includes an optical system adapted to provide light from the second plurality of light sources through the aperture to the object. The system may further include a computer configured to determine the shape of the object and/or the distance of the object from the system using light from the first and second plurality of light sources that is reflected from the object and received by the detector.

Abstract: A method and apparatus provided for controlling fluid control to and from an eye or a phacoemulsification handpiece. The handpiece includes an ultrasonically driven, hollow, sleeved needle and the method includes inserting the needle and sleeve into an eye for phacoemulsification of eye tissue and introducing fluid into the eye through an annulus established between the sleeve and the needle. Aspiration of fragmented tissue and fluid from the eye is conducted through the hollow needle. An initial irrigation fluid pressure is determined and the irrigation fluid flow and aspiration fluid flow are adjusted based upon the initial determination. Thereafter continued determination of irrigation fluid pressure is utilized to continuously adjust irrigation fluid flow and/or aspiration fluid flow.

Abstract: A method for providing a medical product including receiving a request for a medical product for use with a specific patient to be used at a particular location, and creating a patient specific package which includes the medical product. The method further includes associating at least one of the patient specific package or the medical product with the specific patient, and causing the patient specific package to be delivered to the particular location.

Abstract: A method of photoaltering a material using a pulsed laser beam includes selecting a first pulse energy and a first focal point separation based on a relationship of pulse energy and focal point separation combinations enabling layer separation of the material by photoalteration, and scanning the pulsed laser beam along a scan region at the first pulse energy and the first focal point separation. The relationship has a slope and has a distinct change in the slope. The distinct change in the slope is associated with a second pulse energy of the relationships and the first pulse energy is equal to or less than the second pulse energy.

Abstract: A method for charging a deformable intraocular lens into a receptacle through a slit or opening in the receptacle periphery, the lens in un-deformed state comprising a) a roughly disc shaped optic part configured to act as a lens when inserted into an eye and b) at least two elongated haptic legs, each leg having an inner end attached to the optic part, an outer end being free and intermediate points in between the inner end and the free end, each leg being curved in unstressed state and being flexible to at least a less curved configuration under stress. The method comprises the steps of i) stretching the legs to align the legs along a substantially straight line, ii) aligning or maintaining the substantially straight line over and substantially parallel with the slit or opening of the receptacle, and iii) transferring at least the two legs through the slit or opening into the receptacle.

Abstract: A method and apparatus for performing a surgical procedure is provided. The surgical procedure may be a phacoemulsification procedure but other procedures may employ the techniques disclosed. The design includes sensing, within the surgical site, for a material change in fluid flow relative to a predetermined threshold. Upon sensing the fluid flow materially differs from the predetermined threshold, the design temporarily increases aspiration vacuum pressure to the surgical site above a predetermined upper threshold toward a maximum vacuum level. The design applies electrically generated disruptive energy, including but not limited to laser and/or relatively low power ultrasonic energy, to the surgical site from a first point in time measured from when aspiration vacuum pressure is above the predetermined upper threshold to a second point in time where pressure falls below a predetermined lower threshold.

Abstract: A system for providing vision contains an aberrometer, a wavefront sensor, and a transfer optical system. The aberrometer is configured to measure a received wavefront. The aberrometer includes a wavefront sensor and a transfer optical system for transferring an input wavefront so as to the provide the received wavefront at or near the wavefront sensor. The system also includes a processor in communication with the aberrometer, a readable memory, and instructions located within the memory. The readable memory contains one or more system error parameters and instructions available to the processor. The instructions are for determining at least one aberration of the received wavefront and calculating the input wavefront based on the received wavefront and the one or more system error parameters.

Abstract: A method and system for authenticating a user of a medical device is provided. Ocular signatures are stored in a database for at least one permitted user. Stored ocular signatures are compared to an individual ocular signature. The user can employ selected functionality of the medical device when at least one stored ocular signature substantially matches the individual ocular signature. The device may include a medical component and a computing device. The computing device includes a database configured to receive and maintain permitted user ocular signatures and a computational utility configured to compare the ocular signature of the user to at least one permitted user ocular signature maintained in the database. Upon determining that the ocular signature of the user substantially matches at least one permitted user ocular signature, the user is authorized to employ selected functionality of the medical device.

Abstract: A polymeric material with a molecular response time that makes it suitable for use near fragile body tissues. The polymeric material is useful for both low modulus and high modulus applications thereby simplifying the multi-part polymeric article manufacturing process and creating better integrated multi-part polymeric articles. Cross-linked polymers with different moduli may be obtained utilizing the same or similar starting materials but modifying the amount of catalyst, the amount of cross-linking agent, and/or the amount of methyl vinyl cyclics.

Abstract: An atmospheric pressure chemical vapor deposition apparatus has been developed for partially coating acrylic based intraocular lenses. In one embodiment intraocular lenses may be coated with a hydrophilic material comprising silicone dioxide and polyethylene glycol. In another embodiment the haptics may be coated with hydrophilic material, which aids in the post implantation unfolding of the lenses while not diminishing posterior bag adhesion of the hydrophobic surface of the untreated optic portion.