Abstract: The invention is directed to a method and circuitry for controlling dosage rates of a treatment solution. An electric pulse is directed through a coil, inducing a magnetic field and causing a valve to open. A subsequent set of pulses is directed through the coil to maintain the position of the valve. Between pulses, the coil motivates current to flow. Energy associated with the current is captured in a collection circuitry. The method and circuitry may also interpret a signal induced in the coil by an externally applied magnetic field such as that produced by an MIR. The method and circuitry may provide an electric signal to counteract the externally applied magnetic field or to produce a degaussing field.

Abstract: A device and method for generating electrical stimulation. The implantable device includes a programmable switching device or array that receives at least one pulse generator output coupled through at least one coupling capacitor. The switching device selectively connects at least one pulse generator output to a plurality of electrode terminals via at least one coupling capacitor. Electrical stimulation signals may be applied directly from the electrode terminals, or are applied through a lead or lead extension having corresponding electrodes electrically connected to the electrode terminals.

Abstract: In delivering constant current electrical stimulation pulses to electrodes implanted near a stimulation site, a programmable voltage limited mode of operation according to embodiments precludes unsafe voltage spikes upon substantial changes in resistance due to, for example, patient movement. A voltage multiplier of one embodiment is driven by a clock signal stopped whenever an output voltage reaches a predetermined level, and resumed when the output voltage drops below that level. A comparator receiving a voltage-divided output from the voltage multiplier and a variable input control signal from a digital-to-analog converter controls generation of the clock signal according to embodiments.

Abstract: To avoid charge accumulation on capacitive connections to implanted electrodes during delivery of stimulation pulses, stimulation pulses are followed by active discharge pulses having opposite polarity of the stimulation pulses. The active discharge pulses preferably have at least one pulse attribute magnitude (e.g., duration, voltage, and/or current) different than a corresponding stimulation pulse and are preferably programmable. Approximately the same total net current flow is delivered during active discharge pulses as during the stimulation pulses, but in the opposite direction and optionally at a lower amplitude. In addition, by reducing the driving voltage and a variable load within the electrical path for delivery of the pulses, power dissipation during active discharge is preferably reduced.

Abstract: A low power (and lower cost) implementation for amplifier used in delivering a stimulation pulse is provided according to embodiments through use of a pre-charge period for each pulse. For example, a voltage at a variable output terminal of a digital-to-analog converter is increased on the leading edge of PULSE and INVERTCLK signals to result in an output of an operational amplifier increasing to a predetermined voltage prior to output of a stimulation pulse, according to an embodiment. A shunt path may be implemented to shunt current away from a load during the pre-charge period.

Abstract: According to embodiments, amplitude for a stimulation pulse delivered to electrodes implanted within a patient is controlled by a scale circuit and a digital-to-analog converter. The scale circuit selects one of a plurality of overlapping, different sized stimulation pulse amplitude ranges while the digital-to-analog converter selects an amplitude within the selected range. Stimulation pulse amplitude adjustment resolution scales automatically with the selected range, and a lowest range including the desired amplitude is automatically selected.

Abstract: The invention is directed to a dose control apparatus for manipulating the dosage of one or more pharmaceutical solutions emanating from an implantable drug infusion pump. The dose control apparatus has a movable core that is held in a desired position by a magnet. The apparatus has at least one coil that, when activated, motivates the core to move to a new position. The core may be held in the second position by another magnet. The apparatus may have more that one coil provide various control options. In addition, the coils may be used to determine core position or the presence and strength of an externally applied magnetic field such as that produced in an MRI. The coils may also be used to produce a magnetic field counteracting the externally applied field or to produce a degaussing field.

Abstract: The invention relates to a method of treating sexual dysfunction. The method includes stimulating sacral nerve roots, S2 and/or S3, with electromagnetic stimulation in or about the sacrum. The stimulation may be achieved with leads terminating in electrodes that extend with an emerging sacral nerve root or extend transverse the sacrum at or about the location of the nerve root to be stimulated. Alternately, spiraled electrodes and nerve cuffs may be used to stimulate the nerve root within the sacrum, as it emerges from the sacrum, or outside the sacrum. In this manner, the selected sacral nerve root may be stimulated to provide genital stimulation and thereby induce orgasm.

Abstract: Systems and methods provide a programmable or controllable infusate delivery with minimal power consumption using controllable valves and with safe and reliable operation of the delivery system. Embodiments provide programmable control without the need for implantable power sources using multi-stable valves and/or mono-stable valves which are powered externally when activated. Embodiments provide for very low power programmable control, such as by employing micro-electromechanical system valves and a flow restrictor array. An external program controller may be utilized to provide a user interface and which may communicate with the controllable infusate delivery system using wireless links. Internal controller circuitry may provide for flow control changes for different activities or times of day and/or in response to changes in pressure, temperature, etcetera.

Abstract: A method of producing a bio-probe that begins with the step of providing a tapering core of substantially rigid material. The core is then coated with dielectric material and this dielectric material is coated with a first layer of conductive material. The conductive material is then divided into longitudinal traces, extending from the base into proximity to said tip. The conductive material is then coated with a second layer of dielectric material. Finally, portions of the second layer of dielectric material are removed to form apertures to the conductive material, thereby forming electrodes.

Abstract: The present invention relates to a percutaneous insertion-capable lead, wherein insertion is made through a percutaneous insertion structure. For one embodiment of such lead, the electrode-supporting stimulation portion of the lead includes at lease one waisted region, relative to a transverse dimension of the lead, to facilitate lead steerability.

Abstract: The invention is directed to a dose control apparatus. The apparatus has two armatures pressed against a valve seat by at least one spring. A coil induces a magnetic field that motivates the armatures against the force of the spring, thereby opening the valve. The armatures may move along a common axis in opposite directions. The apparatus may also include a core located between the armatures and a casing about the coil. The core and casing act to guide the magnetic field, reducing the power requirements for creating the field. Current may be periodically reversed in the coil to provide a degaussing field. In addition, a signal may be produced by the coil in the presence an externally applied magnetic field such as an MRI. An opposing magnetic field may be produced by the coil or the current provided to the coil may be adjusted.

Abstract: An implantable medical device has a portion formed from a shape memory alloy (SMA) and adapted to connect to another device. At a lower temperature, the SMA is deformed such that the two devices may be mated with low insertion force. At a higher temperature, e.g., the internal temperature of the human body, the SMA attempts to return to its original shape, creating a connection between the two devices and causing a retention force that resists disconnection of the two devices.

Abstract: An implantable lead, and method of manufacturing same, and a system and method for stimulation. The lead has proximal and distal ends having, respectively, a connector portion with a terminal and an electrode. An optically switched device is electrically connected to the electrode and to the terminal. An optical fiber is optically coupled to the connector portion at one end and to the optically switched device at another end. The optically switched device conducts a stimulus from the terminal to the electrode in response to an optical signal transmitted over the optical fiber.

Abstract: The present invention involves a method and a system for using electrical stimulation and/or chemical stimulation to treat depression. More particularly, the method comprises surgically implanting an electrical stimulation lead and/or catheter that is in communication with a predetermined site which is coupled to a signal generator and/or infusion pump that release either an electrical signal and/or a pharmaceutical resulting in stimulation of the predetermined site thereby treating the mood and/or anxiety.

Abstract: The present invention involves a method and a system for using electrical stimulation and/or chemical stimulation to treat depression. More particularly, the method comprises surgically implanting an electrical stimulation lead and/or catheter that is in communication with a predetermined site which is coupled to a signal generator and/or infusion pump that release either an electrical signal and/or a pharmaceutical resulting in stimulation of the predetermined site thereby treating the mood and/or anxiety.

Abstract: An implantable lead, and method of inserting same in a body, and system for stimulation. The lead includes a first lead and a second lead having a connecting member coupled therebetween. The connecting member maintains the first lead and second lead at a first position relative to each other during insertion of the lead and maintains the first lead and second lead at a second position relative to each other after insertion. In one embodiment, the connecting member is constructed of resorbable material to allow non-surgical removal of the lead(s) when desired.

Abstract: According to one embodiment, a neurological stimulation lead is adapted for implantation proximate target nerve tissue in a person for neurological stimulation of the target nerve tissue. A resilient lead body has a generally spiral natural configuration. A plurality of electrodes are located along the resilient lead body and adapted to be positioned proximate the target nerve tissue and to deliver electrical stimulation pulses to the target nerve tissue. The plurality of electrodes are located along the resilient lead body such that the electrodes are arranged in a predetermined array when the resilient lead body is in its generally spiral natural configuration. An inner channel formed through the resilient lead body is adapted to receive a straightening element. When inserted into the inner channel, the straightening element is adapted to place the resilient body in a generally linear configuration for insertion of the lead into the person and positioning of the electrodes proximate the target nerve tissue.

Abstract: An implantable stimulation system including epidural lead for spinal cord stimulation that includes a paddle having a curved proximal end and lateral winged tips and an array of electrodes coupled to conductors within a lead body. The conductors couple to a pulse generator or other stimulation device. The curved and winged paddle provides more complete electrical stimulation coverage to targeted human tissue by minimizing the potential gap between electrodes and targeted fibers.