Abstract: In one embodiment, a stimulation system for generating and delivering electrical stimulation pulse to tissue of a patient, comprises: a pulse generator for generating electrical pulses, the pulse generator comprising a housing portion and a header portion with feedthroughs extending from the housing portion into the header portion; and a stimulation lead comprising a flex film component enclosed in a lead body of insulative material, the flex film component including a plurality of electrically isolated conductors extending along a substantial length of the stimulation lead, the stimulation lead further comprising a plurality of electrodes electrically coupled to the conductors, the flex film component comprising a proximal portion that is exposed out of the insulative material of the lead body and includes a plurality of terminal bond bands, the terminal bond bands being electrically coupled to the conductors; and wherein the header portion of the pulse generator comprises a lid component to compress the ter

Abstract: In one embodiment, a system for wrapping biomedical conductor wires about core material, comprises: a payout assembly and a take-up assembly for controllably paying out the core material and taking up the core material with the wrapped conductor wires; a turntable; a plurality of carriers, disposed on the turntable, for letting out the conductor wires; and a die for applying force to the conductor wires as the wires are wrapped about the core material, the die adapted to rotate according to group rotation of the plurality of carriers by the turntable during operation of the system, wherein the die comprises one or more features asymmetrically arranged about a circumference of the die, the one or more features adapted to direct the conductor wires from the plurality of carriers onto the core material in an axially repeating pattern of groups of closely spaced wires with each group separated by a distance larger than the spacing between adjacent wires within each group.

Abstract: In some embodiments, a paddle lead is implanted within a patient such that the electrodes are positioned within the cervical or thoracic spinal levels. An electrode combination on a first row of electrodes can be determined that is effective for a first pain location with minimal effects on other regions of the body. The first pain location can be addressed by stimulating a first dorsal column fiber due to the relatively fine electrical field resolution achievable by the multiple columns. Then, another electrode combination on a second row of electrodes can be determined for a second pain location with minimal effects on other regions. The second pain location could be addressed by stimulating a second dorsal column fiber. After the determination of the appropriate electrodes for stimulation, the patient's IPG can be programmed to deliver pulses using the first and second rows according to the determined electrode combinations.

Abstract: An implantable, substantially isodiametric, low resistance implantable lead having at least one electrode positioned in a stimulation/sensing portion of the lead as well as a method of manufacturing the same. At least the stimulation/sensing portion is unitized through partially surrounding and supporting insulation and conductive element(s) of the stimulation/sensing portion with a fused matrix of material having mechanical properties consistent with a body of the lead.

Abstract: Nerve cuff electrode including a tubular body having a longitudinal slit having electrodes disposed within the body. Wedge shape slits are formed into at least one of the interior wall and the exterior wall of the body, whereby the number and location of slits provided to facilitate the adjustment of the amount of compressive force of nerve cuff electrode about the nerve.

Abstract: Embodiments herein include an external system and method to detect an implanted lead coupled to an implanted neurostimulation device (INSD). The system and method comprise a handheld probe having electrodes configured to be positioned external to a surface of a patient and proximate to a region of the patient having the implanted lead for an implanted INSD. The electrodes are configured to measure a stimulation output from the implanted lead of the INSD. The system and method include a controller coupled to the electrodes to receive measured signals from the electrodes. The measured signals represent the stimulation output of the INSD. The controller processes the measured signals to obtain lead information. The system includes a user interface to present the lead information to a user. The lead information is indicative of at least one of an operation of the lead and a position of the lead.

Abstract: According to one aspect, a stimulation system is provided for electrically stimulating a predetermined site to treat a fragile bone disorder or condition. The system includes an electrical stimulation lead adapted for implantation into a subcutaneous area in communication with a predetermined site, wherein the site is neuronal tissue that is associated with C2/C3 dermatome area. The stimulation lead includes one or more stimulation electrodes adapted to be positioned in the predetermined site. The system also includes a stimulation source that generates the stimulation pulses for transmission to the one or more stimulation electrodes of the stimulation lead to deliver the stimulation pulses to the predetermined site to treat a fragile bone disorder or condition.

Abstract: In some embodiments, a paddle lead is implanted within a patient such that the electrodes are positioned within the cervical or thoracic spinal levels. An electrode combination on a first row of electrodes can be determined that is effective for a first pain location with minimal effects on other regions of the body. The first pain location can be addressed by stimulating a first dorsal column fiber due to the relatively fine electrical field resolution achievable by the multiple columns. Then, another electrode combination on a second row of electrodes can be determined for a second pain location with minimal effects on other regions. The second pain location could be addressed by stimulating a second dorsal column fiber. After the determination of the appropriate electrodes for stimulation, the patient's IPG can be programmed to deliver pulses using the first and second rows according to the determined electrode combinations.

Abstract: In one embodiment, a method for the controlling of the stimulation pulses being delivered via electrodes to a patient during the programming of a pulse generator using a controller device and selecting of a minimum amplitude that corresponds to the minimum amplitude for which the patient can detect stimulation; selecting an electrode combination defined in the controller device; setting the stimulation amplitude; making a determination of the amplitude for the stimulation pulses is greater than the perception amplitude, and if so, changing the amplitude of the stimulation pulses to be less than or equal to the perception amplitude; and if not or subsequent to the changing of the amplitude, changing the selected one of a plurality of electrode combinations to a different combination.

Abstract: The present invention relates to a multi-column paddle structure and its uses thereof to provide neuromodulation therapy to a patient.

Abstract: Nerve cuff electrode including a tubular body having a longitudinal slit and a flap curled over the slit. The tubular body includes a central cathode disposed between two anodes. The region opposite the slit includes a flexible region that determines the flexibility and strength of tube opening and closing. The cuff electrode having a hinge region with a non-linear effective spring constant which can be higher at low cuff openings and lower at large opening to provide an effective yet non-damaging closing force over a wide range of cuff openings. In use, the tube body can be pulled apart using attached suture loops, with one loop and flap pulled under the nerve followed by part of the tubular body. The tubular body can be closed over the nerve and the flap closed over the tube slit.

Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.

Abstract: In one embodiment, a stimulation lead comprises: a lead body of insulative material surrounding a plurality of conductors; a plurality of electrodes; and a plurality of terminals, the plurality of terminals electrically coupled to the plurality of electrodes through the plurality of conductors; wherein each conductor of the plurality of conductors is helically wound about an axis within the lead body in at least an outer portion and an inner portion relative to the axis, the outer portion comprises a first winding pitch and the inner portion comprises a second winding pitch, the second winding pitch is less than the first winding pitch, the inner portion of each respective conductor being disposed interior to the outer portions of other conductors of the plurality of conductors; wherein an impedance of each conductor of the plurality of conductors substantially reduces MRI-induced current when the stimulation lead is present in an MRI system.

Abstract: In one embodiment, a stimulation lead for applying electrical pulses to tissue of a patient, the stimulation lead comprises: a plurality of electrodes on a first end of the lead body; a plurality of terminals on a second end of the lead body; a lead body comprising a flex film component disposed within insulative material, wherein (i) the flex film component comprises a plurality of electrical traces, (ii) the plurality of electrical traces electrically couple the plurality of electrodes with the plurality of terminals, and (iii) the flex film component comprises a plurality of bends along a substantial length of the lead body; wherein the stimulation lead is adapted to elastically elongate under application of stretching forces to the lead body without disconnection of the electrical connections between the plurality of electrodes and the plurality of terminals through the electrical traces of the flex film component.

Abstract: In one embodiment, a method, for estimating electrode resistance values, comprises: calculating an aggregate resistance value for each electrode in a group of electrodes of an implantable stimulation lead of the electrical stimulation system, wherein the calculating, for each electrode, comprises: (i) setting a respective electrode in the group of electrodes as an anode; (ii) setting electrodes in the group of electrodes other than the respective electrodes as cathodes; (iii) applying a predetermined electrical signal through the group of the electrodes using a pulse generator of the electrical stimulation system; (iv) measuring current flow or voltage resulting from application of the predetermined electrical signal through the group of the electrodes; (v) calculating the aggregate resistance value for the respective electrode in response to the measuring; calculating an individual resistance value for each electrode of the group of electrodes using the set of aggregate resistance values for the group of ele

Abstract: In one embodiment, a method, of operating an IPG, comprises: generating a variable anode voltage by first circuitry to drive current during pulse generation, the first circuitry being programmable to generate the anode voltage from a plurality of voltages in response to a control signal; providing the anode voltage to a first circuit node; operating a transistor to control current flow between the first circuit node and an output of the IPG, wherein the transistor possesses a gate-to-source breakdown voltage; generating a first supply signal that is maintained at a voltage level equal to the anode voltage plus or minus a predetermined amount; and selectively applying the first supply signal and a second supply signal to a gate of the transistor to connect or disconnect the first circuit node in a circuit path with the output of the IPG.

Abstract: A lead, method of manufacturing same, and system for stimulation is provided. The lead includes an insulative member or layer that masks a portion of the electrode(s) to effectively generate a directional lead that focuses or directs the stimulation to desired location(s). In another embodiment, the lead further includes a marking system to allow a clinician to orient the directional lead, as desired, while the lead is within a body.

Abstract: According to one aspect, a stimulation system is provided for electrically stimulating a predetermined site to treat a neurological condition. The system includes an electrical stimulation lead adapted for implantation into a subcutaneous area in communication with a predetermined site, wherein the site is neuronal tissue that is associated with C2/C3 dermatome area, or stimulating cervical nerve roots and/or stimulating cranial nerves and/or stimulating any area associated with the occipital area. The stimulation lead includes one or more stimulation electrodes adapted to be positioned in the predetermined site. The system also includes a stimulation source that generates the stimulation pulses for transmission to the one or more stimulation electrodes of the stimulation lead to deliver the stimulation pulses to the predetermined site to treat a neurological disorder or condition.

Abstract: In one embodiment, a percutaneous stimulation lead for applying electrically stimulation pulses to tissue of the patient comprises: a plurality of electrode assemblies electrically coupled to a plurality of terminals through a plurality of conductors of the stimulation lead, wherein each electrode assembly is disposed in an annular manner around the lead body and each electrode assembly comprises (i) an electrode adapted to deliver electrical stimulation to tissue of a patient, (ii) an interior conductive layer, and (iii) a dielectric layer disposed between the electrode and the interior conductive layer; the electrode and interior conductive layer being capacitively coupled, the dielectric layer further comprising an inductor, the inductor being electrically connected to one of the plurality of conductors through the interior conductive layer, and the inductor being electrically coupled to the electrode.