Abstract: Microscopic particles containing a continuous network of pores open to the particle surface are manufactured of a spongy material. The particles are useful as controlled-release delivery systems for active substances intended for a wide range of uses including topical applications. The spongy character of the particles enhances their usefulness in applications where high pressure or high temperature are encountered, and where exceptional smoothness of feel is required.
Abstract: A reaginic agglutination test for syphilis-associated antibodies is disclosed. The test uses an antigen reagent that comprises a buffered aqueous suspension of cardiolipin antigen ionically coupled to latex particles via a polypeptide bridge. Positive sera react with the antigen reagent and yield an agglutination pattern characterized by medium to large aggregates. Negative sera yield no agglutinated particles.
Abstract: Delivery vehicles comprised of a polymeric bead having a network of pores with an active ingredient held within the network are provided for use in a method to provide controlled release of the active ingredient. The network of pores is substantially non-collapsible upon removal of the active ingredient and the delivery vehicles are polymerized by a process in which the active ingredient also comprises the porogen during formation of the network of pores.