Patents Assigned to Advanced Research & Technology Institute and Ludwig-Maximilians-Universitat Munchen
  • Publication number: 20030181379
    Abstract: The invention relates to novel nucleic acids encoding a fibroblast growth factor-23(FGF23) and proteins encoded thereby, mutations in which are associated with autosomal dominant rickets (ADHR). The invention further relates to methods of diagnosing and treating hypophosphatemic and hyperphosphatemic disorders comprising inhibiting or stimulating, respectively, the biological activity of FGF23 in a patient. The invention also relates to methods of treating osteoporosis, dermatomyositis, and coronary artery disease comprising stimulating the biological activity of FGF23 in a patient.
    Type: Application
    Filed: March 4, 2003
    Publication date: September 25, 2003
    Applicant: Advanced Research & Technology Institute and Ludwig-Maximilians-Universitat Munchen
    Inventors: Michael Econs, Ken White, Tim Matthias Strom, Thomas Meitinger
  • Publication number: 20020156001
    Abstract: The invention relates to novel nucleic acids encoding a fibroblast growth factor-23(FGF23) and proteins encoded thereby, mutations in which are associated with autosomal dominant rickets (ADHR). The invention further relates to methods of diagnosing and treating hypophosphatemic and hyperphosphatemic disorders comprising inhibiting or stimulating, respectively, the biological activity of FGF23 in a patient. The invention also relates to methods of treating osteoporosis, dermatomyositis, and coronary artery disease comprising stimulating the biological activity of FGF23 in a patient.
    Type: Application
    Filed: July 10, 2001
    Publication date: October 24, 2002
    Applicant: Advanced Research & Technology Institute and Ludwig-Maximilians-Universitat Munchen
    Inventors: Michael Econs, Ken White, Tim Matthias Strom, Thomas Meitinger