Abstract: Compositions and methods are disclosed for filling prostheses for implantation into human soft tissue. The compositions comprise at least one nonionic surfactant, such as a polysorbate, which can be provided to fill a physiologically compatible shell or containment sac of the prosthesis. The liquid compositions of the present invention have a relatively high viscosity and are quickly absorbed from body tissues, metabolized and excreted with no known adverse effect. The compositions can be injected into the physiologically compatible shell either before, during or after the surgical implantation procedure.

Abstract: An orthodontic force measuring apparatus includes a dental replica which includes a first tooth replica and a second tooth replica. The first tooth replica is moveable relative to the second tooth replica. The apparatus also includes an orthodontic appliance secured to both the first tooth replica and the second tooth replica of the dental replica. The apparatus further includes a force measuring device operatively coupled to the first tooth replica. The force measuring device is configured so as to measure force exerted on the first tooth replica by the orthodontic appliance. A method of measuring orthodontic force is also disclosed.

Abstract: The present invention provides a method to prevent, inhibit, or reduce dental calculus deposits or formation on the teeth of a dental calculus forming animal comprising exposing the teeth to a food product comprising an acidulent amount of phosphoric acid, wherein said food product further comprises an amount of a polycarboxylic acid sequestering agent effective to prevent, inhibit, or reduce dental calculus deposits or formation. The present invention further provides the food products and the method of preparing the food products of said method.

Abstract: A technique to produce a device for generating an electric field is disclosed. This electric field may be customized to direct movement of charged particles in a predetermined manner. Moreover, this device is readily installed and removed from a charged particle analyzer to facilitate interchange with other devices capable of generating electric fields with different characteristics. The device may be provided by etching an electrically conductive layer clad to a flexible dielectric substrate to define a predetermined conductive pattern. This pattern is then oriented relative to a charged particle pathway and an electric potential applied to generate the desired electric field.

Abstract: The present invention includes purified and isolated quassinoids and synthetically derived quassinoid analogs based on a picrasane carbon skeleton. Novel sidechains at C-15 incorporating water solubilizing agents such as glycine are discussed. Therapeutic methods taking advantage of anticancer, antiviral, and herbistatic properties of these quassinoids are disclosed, including use against solid tumors and human immunodeficiency virus infected cells.

Abstract: Devices and methods are disclosed for the percutaneous administration of a composition to a desired in vivo location. The composition comprises a biologically active substance and a pharmaceutically acceptable carrier. The pharmaceutically acceptable carrier is preferably non-solid and a polymer, which is preferably capable of being transformed into a gel, thus allowing timed-released delivery of the substance. A preferred use for this invention is to provide local delivery of biologically active substances for the prevention of restenosis following angioplasty or other blood vessel injury.

Abstract: The present invention includes purified and isolated quassinoids and synthetically derived quassinoid analogs based on a picrasane carbon skeleton. Novel sidechains at C-15 incorporating water solubilizing agents such as glycine are discussed. Therapeutic methods taking advantage of anticancer, antiviral, and herbistatic properties of these quassinoids are disclosed, including use against solid tumors and human immunodeficiency virus infected cells.

Abstract: Described are unique preferred enzyme coacervate compositions and their use in catalyzing the reaction of substrates to which the enzyme is specific. Preferred coacervates of the invention are complex coacervates formed by complexing enzymes with polyelectrolytes.