Patents Assigned to Advanced Technology Applications, LLC
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Publication number: 20190083981Abstract: An apparatus comprises a biosensor disk structure including a first substrate with a first inner surface, a second substrate with a second inner surface facing oppositely toward the first inner surface, and fluidic channels reaching between the first and second inner surfaces; wherein the first inner surface has binding sites and non-binding sites adjoining the binding sites, the first substrate is transparent at the non-binding sites, and the non-binding sites have discrete polygonal configurations of equal size and shape; and the second inner surface has non-reflective areas and reflective areas bounded by the non-reflective areas, and the reflective areas have discrete polygonal configurations sized and shaped equally with the non-binding sites such that the reflective areas are located coextensively opposite the non-binding sites.Type: ApplicationFiled: August 7, 2018Publication date: March 21, 2019Applicant: Advanced Technology Applications, LLCInventors: Jeffery R.X. Auld, James E. Smith
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Patent number: 10040066Abstract: A biosensor disk includes a detection substrate with an upper side surface, a reflection substrate with a lower side surface facing oppositely toward the upper side surface, and fluidic channels reaching between the opposed side surfaces. The upper side surface has binding sites, and has non-binding sites adjoining the binding sites. The detection substrate is transparent at the non-binding sites. The lower side surface has non-reflective areas, and has reflective areas adjoining the non-reflective areas. The reflective areas are located opposite the non-binding sites and have discrete polygonal configurations of equal size and shape.Type: GrantFiled: May 27, 2015Date of Patent: August 7, 2018Assignee: Advanced Technology Applications, LLCInventor: Jeffery R. X. Auld
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Publication number: 20160303560Abstract: A biosensor disk includes a detection substrate with an upper side surface, a reflection substrate with a lower side surface facing oppositely toward the upper side surface, and fluidic channels reaching between the opposed side surfaces. The upper side surface has binding sites, and has non-binding sites adjoining the binding sites. The detection substrate is transparent at the non-binding sites. The lower side surface has non-reflective areas, and has reflective areas adjoining the non-reflective areas. The reflective areas are located opposite the non-binding sites and have discrete polygonal configurations of equal size and shape.Type: ApplicationFiled: May 27, 2015Publication date: October 20, 2016Applicant: Advanced Technology Applications, LLCInventor: Jeffery R.X. Auld
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Patent number: 8735846Abstract: A system, method, device, and process for making and using an electromagnetic-sensitive biosensor on a biosensor disk to identify and classify an analyte in a sample. The biosensor of the biosensor disk is exposed to a sample containing analytes and a desired analyte adheres to the biosensor. The biosensor is exposed to microspheres that adhere to the analyte. The microspheres cause a detectable change to electromagnetic radiation incident upon the biosensor disk The biosensor disk is rotated during operation and an electromagnetic emitter directs an electromagnetic radiation beam at the biosensor disk. The returned electromagnetic radiation from the biosensor disk is received by a sensor and converted into a signal to indicate the presence of the desired analyte in the sample.Type: GrantFiled: October 11, 2010Date of Patent: May 27, 2014Assignee: Advanced Technology Applications, LLCInventor: Jeffery R. X. Auld
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Patent number: 7812318Abstract: A system, method, device, and process for making and using an electromagnetic-sensitive biosensor on a biosensor disk to identify and classify an analyte in a sample. The biosensor of the biosensor disk is exposed to a sample containing analytes and a desired analyte adheres to the biosensor. The biosensor disk is rotated during operation and an electromagnetic emitter directs an electromagnetic radiation beam at the biosensor disk. The returned electromagnetic radiation from the biosensor disk is received by a sensor that converts the returned electromagnetic radiation into a signal to indicate the presence of the desired analyte in the sample.Type: GrantFiled: March 14, 2008Date of Patent: October 12, 2010Assignee: Advanced Technology Applications, LLCInventor: Jeffrey R. X. Auld