Abstract: A mechanical holder that provides for a confined sampling region for extraction and removal of chemical substances contained in a dried blood spot or other spot of sample is described herein.
Type:
Application
Filed:
July 30, 2012
Publication date:
November 15, 2012
Applicant:
Advion BioSystems, Inc.
Inventors:
Daniel EIKEL, John D. HENION, Christopher ALPHA, Jason Scott VEGA
Abstract: Methods and systems for mass spectrometry and more particularly to an interface providing charged particles to a mass spectrometer are described herein.
Type:
Application
Filed:
August 18, 2011
Publication date:
April 26, 2012
Applicant:
ADVION BIOSYSTEMS, INC.
Inventors:
Simon Prosser, Jack Henion, Stephen Thompson, Vic Parr
Abstract: A mechanical holder that provides for a confined sampling region for extraction and removal of chemical substances contained in a dried blood spot or other spot of sample is described herein.
Type:
Application
Filed:
May 4, 2011
Publication date:
January 26, 2012
Applicant:
ADVION BIOSYSTEMS, INC.
Inventors:
Daniel Eikel, John D. Henion, Christopher Alpha, Jason Scott Vega
Abstract: A liquid chromatography/mass spectrometry system includes a chromatographic column through which an effluent passes, wherein the effluent comprises a plurality of analytes that correspond to a plurality of chromatographic peaks and an eluent; a post-column splitter having at least two output ports through which the effluent of the column is split to at least a first portion and a second portion; a mass spectrometer configured to receive the first portion from a first of the output ports for analysis; and a tube connected to a second of the output ports configured to prevent substantial evaporation of the eluent in the second portion until undergoing mass spectrometry. The second portion has a plurality of separated analytes corresponding to at least two chromatographic peaks. A method of using the system is also disclosed.
Type:
Grant
Filed:
March 21, 2008
Date of Patent:
September 21, 2010
Assignee:
Advion BioSystems, Inc.
Inventors:
Gary A. Schultz, Reinaldo Rodrigo Queiros de Almeida, Mark Haydn Allen