Patents Assigned to Adynxx, Inc.
  • Oligonucleotide decoys for the treatment of pain
    Patent number: 10287583
    Abstract: Provided are therapeutic agents such as double-stranded nucleic acids, termed oligonucleotide decoys, pharmaceutical compositions comprising the same, and related methods of modulating nociceptive signaling, for instance, to prevent and/or treat pain.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: May 14, 2019
    Assignee: Adynxx, Inc.
    Inventors: Julien Mamet, Rick Orr, Don Manning, Scott Harris, William Martin
  • Gene expression and pain
    Patent number: 10041069
    Abstract: The present invention relates to double-stranded oligonucleotides, pharmaceutical compositions thereof, and use of such double-stranded oligonucleotides and pharmaceutical compositions to modulate nociceptive signaling in a cell or prevent and/or treat pain in a patient.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: August 7, 2018
    Assignee: Adynxx, Inc.
    Inventor: Julien Mamet
  • FORMULATIONS FOR THE DELIVERY OF ACTIVE INGREDIENTS
    Publication number: 20180015165
    Abstract: This invention relates generally to in vivo delivery of active ingredient formulations. More particularly, this invention relates to formulations of active ingredients that further comprise an agent, methods of making such formulations, and methods of using the same.
    Type: Application
    Filed: April 5, 2017
    Publication date: January 18, 2018
    Applicant: Adynxx, Inc.
    Inventors: Julien Mamet, Scott Harris, George Miljanich, Rick Orr, William K. Schmidt, Tony Yaksh, David C. Yeomans
  • Formulations for the delivery of active ingredients
    Patent number: 9700624
    Abstract: This invention relates generally to in vivo delivery of active ingredient formulations. More particularly, this invention relates to formulations of active ingredients that further comprise an agent, methods of making such formulations, and methods of using the same.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: July 11, 2017
    Assignee: Adynxx, Inc.
    Inventors: Julien Mamet, Scott Harris, George Miljanich, Rick Orr, William K Schmidt, Tony Yaksh, David C Yeomans
  • Gene expression and pain
    Patent number: 9290762
    Abstract: The present invention relates to double-stranded oligonucleotides, pharmaceutical compositions thereof, and use of such double-stranded oligonucleotides and pharmaceutical compositions to modulate nociceptive signaling in a cell or prevent and/or treat pain in a patient.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: March 22, 2016
    Assignee: Adynxx, Inc.
    Inventor: Julien Mamet
  • GENE EXPRESSION AND PAIN
    Publication number: 20140343132
    Abstract: The present invention relates to double-stranded oligonucleotides, pharmaceutical compositions thereof, and use of such double-stranded oligonucleotides and pharmaceutical compositions to modulate nociceptive signaling in a cell or prevent and/or treat pain in a patient.
    Type: Application
    Filed: April 22, 2014
    Publication date: November 20, 2014
    Applicant: Adynxx, Inc.
    Inventor: Julien Mamet
  • Gene expression and pain
    Patent number: 8741864
    Abstract: The present invention relates to double-stranded oligonucleotides, pharmaceutical compositions thereof, and use of such double-stranded oligonucleotides and pharmaceutical compositions to modulate nociceptive signaling in a cell or prevent and/or treat pain in a patient.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: June 3, 2014
    Assignee: Adynxx, Inc
    Inventor: Julien Mamet
  • GENE EXPRESSION AND PAIN
    Publication number: 20120232131
    Abstract: The present invention relates to double-stranded oligonucleotides, pharmaceutical compositions thereof, and use of such double-stranded oligonucleotides and pharmaceutical compositions to modulate nociceptive signaling in a cell or prevent and/or treat pain in a patient.
    Type: Application
    Filed: December 9, 2011
    Publication date: September 13, 2012
    Applicant: ADYNXX, INC.
    Inventor: Julien MAMET
  • Gene expression and pain
    Patent number: 8093225
    Abstract: The present invention relates to double-stranded oligonucleotides, pharmaceutical compositions thereof, and use of such double-stranded oligonucleotides and pharmaceutical compositions to modulate nociceptive signaling in a cell or prevent and/or treat pain in a patient.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: January 10, 2012
    Assignee: Adynxx, Inc.
    Inventor: Julien Mamet
  • GENE EXPRESSION AND PAIN
    Publication number: 20110166212
    Abstract: The present invention relates to double-stranded oligonucleotides, pharmaceutical compositions thereof, and use of such double-stranded oligonucleotides and pharmaceutical compositions to modulate nociceptive signaling in a cell or prevent and/or treat pain in a patient.
    Type: Application
    Filed: March 15, 2011
    Publication date: July 7, 2011
    Applicant: ADYNXX, INC.
    Inventor: Julien MAMET
  • Gene expression and pain
    Patent number: 7943591
    Abstract: The present invention relates to double-stranded oligonucleotides, pharmaceutical compositions thereof, and use of such double-stranded oligonucleotides and pharmaceutical compositions to modulate nociceptive signaling in a cell or prevent and/or treat pain in a patient.
    Type: Grant
    Filed: May 12, 2008
    Date of Patent: May 17, 2011
    Assignee: Adynxx, Inc.
    Inventor: Julien Mamet
  • GENE EXPRESSION AND PAIN
    Publication number: 20080300209
    Abstract: The present invention relates to double-stranded oligonucleotides, pharmaceutical compositions thereof, and use of such double-stranded oligonucleotides and pharmaceutical compositions to modulate nociceptive signaling in a cell or prevent and/or treat pain in a patient.
    Type: Application
    Filed: May 12, 2008
    Publication date: December 4, 2008
    Applicant: ADYNXX, INC.
    Inventor: Julien Mamet