Abstract: Provided are therapeutic agents such as double-stranded nucleic acids, termed oligonucleotide decoys, pharmaceutical compositions comprising the same, and related methods of modulating nociceptive signaling, for instance, to prevent and/or treat pain.
Type:
Grant
Filed:
March 19, 2019
Date of Patent:
June 16, 2020
Assignee:
ADYNXX SUB, INC.
Inventors:
Julien Mamet, Rick Orr, Donald C. Manning, Scott Harris, William Martin
Abstract: This invention relates generally to in vivo delivery of active ingredient formulations. More particularly, this invention relates to formulations of active ingredients that further comprise an agent, methods of making such formulations, and methods of using the same.
Type:
Grant
Filed:
April 5, 2017
Date of Patent:
October 8, 2019
Assignee:
Adynxx Sub, Inc.
Inventors:
Julien Mamet, Scott Harris, George Miljanich, Rick Orr, William K. Schmidt, Tony Yaksh, David C. Yeomans