Patents Assigned to Aegis Therapeutics, Inc.
  • COMPOSITIONS FOR ORAL DRUG ADMINISTRATION
    Publication number: 20140162965
    Abstract: The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject. The compositions include at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms. In various aspects, the invention provides compositions and methods for oral delivery in the form of a tablet.
    Type: Application
    Filed: July 25, 2013
    Publication date: June 12, 2014
    Applicant: AEGIS THERAPEUTICS, INC.
    Inventor: Edward T. Maggio
  • COMPOSITIONS FOR DRUG ADMINISTRATION
    Publication number: 20140107145
    Abstract: The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject. The compositions include at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms.
    Type: Application
    Filed: December 18, 2013
    Publication date: April 17, 2014
    Applicant: AEGIS THERAPEUTICS, INC.
    Inventor: Edward T. Maggio
  • COMPOSITIONS FOR DRUG ADMINISTRATION
    Publication number: 20120021980
    Abstract: The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject. The compositions include at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms. In various aspects, the invention provides compositions and methods for oral delivery of glucagon-like peptide-1 analogs, such as exenatide, albiglutide, taspoglutide, liraglutide and lixisenatide.
    Type: Application
    Filed: July 26, 2011
    Publication date: January 26, 2012
    Applicant: AEGIS THERAPEUTICS, INC.
    Inventor: Edward T. Maggio
  • Stabilizing alkylglycoside compositions and methods thereof
    Patent number: 8076290
    Abstract: The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or variant thereof, for example insulin and Peptide T or analog thereof.
    Type: Grant
    Filed: November 9, 2007
    Date of Patent: December 13, 2011
    Assignee: Aegis Therapeutics, Inc.
    Inventor: Edward T. Maggio
  • COMPOSITIONS FOR DRUG ADMINISTRATION
    Publication number: 20110257096
    Abstract: The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject. The compositions include at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms. In various aspects, the invention provides compositions and methods for oral delivery of peptides containing non-naturally occurring structures including D-amino acids and/or chain cyclization.
    Type: Application
    Filed: October 18, 2010
    Publication date: October 20, 2011
    Applicant: AEGIS THERAPEUTICS, INC.
    Inventor: Edward T. Maggio
  • Compositions for Drug Administration
    Publication number: 20090047347
    Abstract: The present invention provides compositions and methods and for speeding the onset of drug action and reducing the first-pass effect drug metabolism in fast-dispersing drug formulations.
    Type: Application
    Filed: August 20, 2008
    Publication date: February 19, 2009
    Applicant: AEGIS THERAPEUTICS, INC.
    Inventor: Edward T. Maggio
  • Stabilizing alkylglycoside compositions and methods thereof
    Patent number: 7425542
    Abstract: The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or variant thereof, for example insulin and Peptide T or analog thereof.
    Type: Grant
    Filed: June 23, 2006
    Date of Patent: September 16, 2008
    Assignee: Aegis Therapeutics, Inc.
    Inventor: Edward T. Maggio
  • COMPOSITIONS FOR DRUG ADMINISTRATION
    Publication number: 20080200418
    Abstract: A composition having at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms and wherein the therapeutic agent is an oligonucleotide.
    Type: Application
    Filed: February 25, 2008
    Publication date: August 21, 2008
    Applicant: AEGIS THERAPEUTICS, INC.
    Inventor: Edward T. Maggio