Patents Assigned to Aeolus Pharmaceuticals, Inc.
  • Substituted Porphyrins
    Publication number: 20110065679
    Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: September 17, 2010
    Publication date: March 17, 2011
    Applicant: Aeolus Pharmaceuticals, Inc.
    Inventors: James D. Crapo, Brian J. Day, Michael P. Trova, Polvina Jolicia F. Gauuan, Douglas B. Kitchen, Irwin Fridovich, Ines Batinic-Haberle
  • Oxidant scavengers
    Patent number: 7470677
    Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating intra- and extracellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Grant
    Filed: June 9, 2003
    Date of Patent: December 30, 2008
    Assignee: Aeolus Pharmaceuticals, Inc.
    Inventors: James D. Crapo, Irwin Fridovich, Tim Oury, Brian J. Day, Rodney J. Folz, Bruce A. Freeman, Michael P. Trova, Ines Batinic-Haberle
  • Substituted porphyrins
    Publication number: 20040023941
    Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: January 23, 2003
    Publication date: February 5, 2004
    Applicants: NATIONAL JEWISH MEDICAL AND RESEARCH CENTER, AEOLUS PHARMACEUTICALS, INC., DUKE UNIVERSITY
    Inventors: James D. Crapo, Brian J. Day, Michael P. Trova, Polivina Jolicia F. Gauuan, Douglas B. Kitchen, Irwin Fridovich, Ines Batinic-Haberle
  • Oxidant scavengers
    Publication number: 20040019031
    Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating intra- and extracellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: June 9, 2003
    Publication date: January 29, 2004
    Applicants: DUKE UNIVERSITY, UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION, AEOLUS PHARMACEUTICALS, INC.
    Inventors: James D. Crapo, Irwin Fridovich, Tim Oury, Brian J. Day, Rodney J. Folz, Bruce A. Freeman, Michael P. Trova, Ines Batinic-Haberle
  • Oxidant scavengers
    Patent number: 6583132
    Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating intra- and extracellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Grant
    Filed: November 30, 1998
    Date of Patent: June 24, 2003
    Assignees: Duke University, University of Alabama at Birmingham Research Foundation, Aeolus Pharmaceuticals, Inc.
    Inventors: James D. Crapo, Irwin Fridovich, Tim Oury, Brian J. Day, Rodney J. Folz, Bruce A. Freeman, Michael P. Trova, Ines Batinic-Haberle
  • Substituted porphyrins
    Patent number: 6544975
    Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Grant
    Filed: January 25, 2000
    Date of Patent: April 8, 2003
    Assignees: National Jewish Medical and Research Center, Aeolus Pharmaceuticals INC, Duke University
    Inventors: James D. Crapo, Brian J. Day, Michael P. Trova, Polivina Jolicia F. Gauuan, Douglas B. Kitchen, Irwin Fridovich, Ines Batinic-Haberle
  • Substituted porphyrins
    Patent number: 6479477
    Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods. Compounds of the invention include those of Formula I.
    Type: Grant
    Filed: April 23, 1999
    Date of Patent: November 12, 2002
    Assignees: Duke University, Aeolus Pharmaceuticals, Inc.
    Inventors: James D. Crapo, Brian J. Day, Polivina Jolicia F. Gauuan, Anthony D. Pechulis, Jr., Michael P. Trova