Abstract: This invention relates to a combination drug product comprising pioglitazone hydrochloride and a biguamide, e.g. metformin. In particular, the product comprises a core of the biguamide, e.g. metformin, at least a portion thereof has a layer or coat thereon of pioglitazone.
Type:
Grant
Filed:
October 31, 2000
Date of Patent:
August 24, 2004
Assignee:
Aeropharm Technology, Inc.
Inventors:
Anthony J. Cutie, Akwete L. Adjei, Frederick A. Sexton
Abstract: A polymeric construct is disclosed. The construct comprises a polysaccharide polymer having a selected medicament associated therewith. The medicament thus present is provided in a slow release form.
Type:
Grant
Filed:
February 15, 2001
Date of Patent:
June 15, 2004
Assignee:
Aeropharm Technology, Inc.
Inventors:
Yaping Zhu, Simon G. Stefanos, Lukeysha Kline, Akwete L. Adjei
Abstract: This invention relates to a modulating formulation comprising pioglitazone hydrochloride and a biguamide, e.g. metformin. In particular, the product comprises a core of the biguamide, e.g. metformin, at least a portion thereof has a layer or coat thereon of pioglitazone.
Type:
Grant
Filed:
February 15, 2001
Date of Patent:
February 25, 2003
Assignee:
Aeropharm Technology Inc.
Inventors:
Akwete L. Adjei, Yaping Zhu, Anthony J. Cutie
Abstract: A non-aqueous medicinal aerosol formulation comprising rosiglitazone maleate, a fluid carrier, and an amino acid stabilizer. The aerosol formulation may also include drug combination formulations comprising rosiglitazone maleate and a second anti-diabetic medicament.
Type:
Grant
Filed:
October 31, 2000
Date of Patent:
October 22, 2002
Assignee:
Aeropharm Technology, Inc.
Inventors:
Anthony J. Cutie, Akwete L. Adjei, Frederick A. Sexton
Abstract: This invention relates to a controlled-release combination drug product comprising troglitazone, e.g. its hydrochloride, and a biguamide, e.g. metformin. In particular, the product comprises a core of metformin, at least a portion thereof has a layer or coat thereon of troglitazone.
Type:
Grant
Filed:
February 15, 2001
Date of Patent:
October 8, 2002
Assignee:
Aeropharm Technology, Inc.
Inventors:
Akwete L. Adjei, Yaping Zhu, Anthony J. Cutie
Abstract: A method of treating a systemic disease in a patient in need of such treatment is disclosed. The method comprising maintaining the inspiratory flow rate and volume of the patient to a certain value and then administering a medicament aerosol formulation to such patient.
Abstract: This invention relates to a medicinal aerosol formulation and more particularly, to a medicinal aerosol formulation containing a particulate drug, a propellant and a stabilizing agent selected from an amino acid, an amino acid derivative and a mixture of the foregoing.
Abstract: Aerosol formulations for mucosal and/or topical administration containing one or more drugs and a sugar as a dispersant in a pharmaceutically acceptable propellant, are disclosed. Metered dose inhalers suitable for delivering such formulations are also disclosed.