Abstract: The present disclosure relates to aptamers, polynucleotides, and nuclei acid molecules, which include a polynucleotide sequence capable of specifically binding polypeptides participating in M. hyopneumoniae infection. Also provided are methods of using nucleic acid molecules, polynucleotides and synthetic antibodies directed there against for detection, treating and neutralization of M. hyopneumoniae infection.
Type:
Grant
Filed:
March 3, 2022
Date of Patent:
September 12, 2023
Assignee:
AEROVIRUS TECHNOLOGIES INC.
Inventors:
Norman J Marchand, Thomas G Caltagirone, Albert Liao
Abstract: Disclosed herein are devices and methods for the real-time detection of aeropathogens. The device includes an aerosampler having an air inlet and at least one collector tube, a microfluidic system which includes a container, piping, a micro-pump for flowing a liquid, and a viral detection chamber. The viral detection chamber has an electrode which may be equipped with functionalized biosensors, a counter electrode, an electronic detection system connectable to the electrodes of the viral detection chamber, and an embedded electronic processing system for processing data from the electronic detection system.
Abstract: The invention provides a device and method for the real-time detection of aeropathogens. The device includes an aerosampler having an air inlet and at least one collector tube, a microfluidic system which includes a container, piping, a micro pump for flowing a liquid and a viral detection chamber. The viral detection chamber has an electrode which may be equipped with functionalized bio sensors, a counter electrode, an electronic detection system connectable to the electrodes of the viral detection chamber, and an embedded electronic processing system for processing data from the electronic detection system.
Abstract: Aptamers, polynucleotides which participate in preventing the Porcine Respiratory and Reproductive Syndrome virus (PRRSV) infection of cells, and nucleic acid molecules, which include a polynucleotide sequence capable of specifically binding the polypeptides domain of the PRRSV that controls infection, constitute the core of the present invention. Also provided are methods of using such nucleic acid molecules, polynucleotides and synthetic antibodies directed against these, for detection, treating and neutralization of PRRSV infection.
Type:
Grant
Filed:
December 1, 2016
Date of Patent:
May 11, 2021
Assignee:
AEROVIRUS TECHNOLOGIES INC.
Inventors:
Norman Marchand, Thomas Caltagirone, Albert Liao
Abstract: The present invention relates to aptamers, polynucleotides, and nucleic acid molecules, which include a polynucleotide sequence capable of specifically binding polypeptides participating in M. Hyopneumoniae infection. Also provided are methods of using nucleic acid molecules, polynucleotides and synthetic antibodies directed there against for detection, treating and neutralization of M. Hyopneumoniae infection.
Type:
Application
Filed:
August 30, 2017
Publication date:
August 1, 2019
Applicant:
AEROVIRUS TECHNOLOGIES INC.
Inventors:
Norman J MARCHAND, Thomas G CALTAGIRONE, Albert Liao