Patents Assigned to AFFEMED GMBH
  • Antibody binding sites specific for EGFRvIII
    Patent number: 10273309
    Abstract: This application describes binding proteins that specifically bind to EGFRvIII and multispecific binding proteins that specifically bind to EGFRvIII and CD3. Further described is a multispecific tandem diabody that binds to EGFRvIII and CD3. Further described are highly cytotoxic EGFRvIII/CD3 bispecific tandem diabody for recruiting T cells to specifically and potently kill several types of solid tumor cancer.
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: April 30, 2019
    Assignee: AFFEMED GMBH
    Inventors: Kristina Ellwanger, Uwe Reusch, Ivica Fucek, Stefan Knackmuss, Vera Molkenthin, Melvyn Little, Eugene Zhukovsky