Patents Assigned to Affera, Inc.
  • Patent number: 12178499
    Abstract: Ablation systems of the present disclosure facilitate the safe formation of wide and deep lesions. For example, ablation systems of the present disclosure can allow for the flow of irrigation fluid and blood through an expandable ablation electrode, resulting in efficient and effective cooling of the ablation electrode as the ablation electrode delivers energy at a treatment site of the patient. Additionally, or alternatively, ablation systems of the present disclosure can include a deformable ablation electrode and a plurality of sensors that, in cooperation, sense the deformation of the ablation electrode, to provide a robust indication of the extent and direction of contact between the ablation electrode and tissue at a treatment site.
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: December 31, 2024
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Ian Matthew Collier, Andrew Miles Wallace, Jonathan Matthew Bond
  • Patent number: 12161422
    Abstract: Systems and methods present multiple images of a three-dimensional model, including a three-dimensional representation of an anatomic structure and a representation of a medical device relative to the anatomic structure, on a graphical user interface. The multiple images correspond to different views (e.g., in multiple, different planes) of the three-dimensional model to provide complementary spatial information regarding a position of the medical device relative to the anatomic structure during a medical procedure performed on the anatomic structure. Such complementary spatial information can, for example, provide spatial context to facilitate controlling the position of the medical device relative to the anatomic structure during the medical procedure.
    Type: Grant
    Filed: March 14, 2023
    Date of Patent: December 10, 2024
    Assignee: AFFERA, INC.
    Inventors: Geoffrey Peter Wright, Doron Harlev
  • Patent number: 12161399
    Abstract: Devices, systems, and methods of the present disclosure are directed to controlling distribution of electrical energy moving from an ablation electrode at a treatment site within a patient to a plurality of return electrodes on skin of the patient. Control over the distribution of electrical energy moving from the ablation electrode to the plurality of return electrodes can reduce or eliminate the need for manual intervention (e.g., repositioning the plurality of return electrodes on the skin of the patient, repositioning the patient, etc.) to achieve a suitable distribution of the electrical energy. Additionally, or alternatively, the devices, systems, and methods of the present disclosure can respond rapidly and automatically to changes in distribution of the electrical energy to reduce the likelihood and magnitude of inadvertent changes in the distribution of electrical energy over the course of a medical procedure.
    Type: Grant
    Filed: September 27, 2022
    Date of Patent: December 10, 2024
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Ilya Bystryak, Alexander Shrabstein, Yanko K. Sheiretov, Joseph Harlev, Paul B. Hultz
  • Patent number: 12114922
    Abstract: Ablation systems and methods of the present disclosure include a catheter including one or more image sensors. The one or more image sensors can facilitate, for example, positioning an ablation electrode at a treatment site of an anatomic structure and, additionally or alternatively, can facilitate controlling delivery of therapeutic energy to a treatment site of an anatomic structure.
    Type: Grant
    Filed: March 2, 2023
    Date of Patent: October 15, 2024
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Andrew Miles Wallace
  • Patent number: 12114921
    Abstract: Ablation systems and methods of the present disclosure include a catheter including one or more image sensors. The one or more image sensors can facilitate, for example, positioning an ablation electrode at a treatment site of an anatomic structure and, additionally or alternatively, can facilitate controlling delivery of therapeutic energy to a treatment site of an anatomic structure.
    Type: Grant
    Filed: June 14, 2022
    Date of Patent: October 15, 2024
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Andrew Miles Wallace
  • Patent number: 12096976
    Abstract: Devices, systems, and methods of the present disclosure are directed to selectively controlling delivery of electrical energy to an ablation electrode, with the selective control based on a history of the electrical energy delivered to a return electrode (e.g., electrical energy delivered in a current time-step and in one or more time-steps preceding the current time-step). Controlling electrical energy delivered to an ablation electrode based on the history of electrical energy delivered to a return electrode can reduce the likelihood of unintended tissue damage away from a treatment site as electrical energy is delivered to the treatment site via the ablation electrode. Further, or instead, the devices, systems, and methods of the present disclosure can reduce the likelihood of unintended tissue damage away from the treatment site while reducing or eliminating the need to interrupt lesion formation by the ablation electrode.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: September 24, 2024
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Paul B. Hultz, Robert Alan Mest
  • Patent number: 12064168
    Abstract: Ablation systems of the present disclosure facilitate the safe formation of wide and deep lesions. For example, ablation systems of the present disclosure can allow for the flow of irrigation fluid and blood through an expandable ablation electrode, resulting in efficient and effective cooling of the ablation electrode as the ablation electrode delivers energy at a treatment site of the patient. Additionally, or alternatively, ablation systems of the present disclosure can include a deformable ablation electrode and a plurality of sensors that, in cooperation, sense the deformation of the ablation electrode, to provide a robust indication of the extent and direction of contact between the ablation electrode and tissue at a treatment site.
    Type: Grant
    Filed: October 12, 2020
    Date of Patent: August 20, 2024
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Ian Collier, Andrew Miles Wallace, Jonathan Matthew Bond
  • Patent number: 12035965
    Abstract: Ablation systems of the present disclosure facilitate the safe formation of wide and deep lesions. For example, ablation systems of the present disclosure can allow for the flow of irrigation fluid and blood through an expandable ablation electrode, resulting in efficient and effective cooling of the ablation electrode as the ablation electrode delivers energy at a treatment site of the patient. Additionally, or alternatively, ablation systems of the present disclosure can include a deformable ablation electrode and a plurality of sensors that, in cooperation, sense the deformation of the ablation electrode, to provide a robust indication of the extent and direction of contact between the ablation electrode and tissue at a treatment site.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: July 16, 2024
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Andrew Miles Wallace, Ian Collier, Jonathan Matthew Bond
  • Patent number: 11986237
    Abstract: Ablation systems and methods of the present disclosure control lesion depth and width such that, for example, wide and shallow lesions can be formed in target tissue in an anatomic structure of a patient during a medical procedure. Such wide and shallow lesions can be useful for treating, for example, thin tissue such as atrial tissue in atria of the heart of the patient.
    Type: Grant
    Filed: October 6, 2021
    Date of Patent: May 21, 2024
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Andrew Miles Wallace, Luke Tsai
  • Patent number: 11954815
    Abstract: Systems and methods of automatically controlling, on a graphical user interface used by a physician, display views of an anatomic structure of a patient. Such systems and methods of automatically controlling display views of an anatomic structure of a patient can facilitate visualizing a position of a medical device relative to the anatomic structure during a medical procedure directed to the anatomic structure. In certain implementations, the systems and methods of the present disclosure provide automatic display views of a cardiac catheter relative to a three-dimensional model of a patient's heart cavity during a medical procedure such as cardiac ablation.
    Type: Grant
    Filed: April 27, 2023
    Date of Patent: April 9, 2024
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Geoffrey Peter Wright
  • Patent number: 11826095
    Abstract: Ablation systems of the present disclosure facilitate the safe formation of wide and deep lesions. For example, ablation systems of the present disclosure can allow for the flow of irrigation fluid and blood through an expandable ablation electrode, resulting in efficient and effective cooling of the ablation electrode as the ablation electrode delivers energy at a treatment site of the patient. Additionally, or alternatively, ablation systems of the present disclosure can include a deformable ablation electrode and a plurality of sensors that, in cooperation, sense the deformation of the ablation electrode, to provide a robust indication of the extent and direction of contact between the ablation electrode and tissue at a treatment site.
    Type: Grant
    Filed: November 15, 2021
    Date of Patent: November 28, 2023
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Ian Collier, Andrew Miles Wallace, Jonathan Matthew Bond
  • Patent number: 11793567
    Abstract: Devices, systems, and methods of the present disclosure can overcome physical constraints associated with catheter introduction to facilitate the use of a catheter with a large distal portion as part of a medical procedure benefitting from such a large distal portion, such as, for example, cardiac ablation. More specifically, devices, systems, and methods of the present disclosure can compress an expandable tip of a catheter from an expanded state to a compressed state along a tapered surface of an insertion sleeve for advancement of the expandable tip into vasculature of a patient. The tapered surface of the insertion sleeve can, for example, apply compressive forces at an angle against the advancing expandable tip. As compared to other approaches to the application of compressive force to an expandable tip, compressing the expandable tip using an angled force can reduce the likelihood of unintended deformation of the expandable tip.
    Type: Grant
    Filed: September 2, 2022
    Date of Patent: October 24, 2023
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Andrew Miles Wallace, Luke Tsai, Ian Matthew Collier
  • Patent number: 11759255
    Abstract: Ablation systems and methods of the present disclosure control lesion depth and width such that, for example, wide and shallow lesions can be formed in target tissue in an anatomic structure of a patient during a medical procedure. Such wide and shallow lesions can be useful for treating, for example, thin tissue such as atrial tissue in atria of the heart of the patient.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: September 19, 2023
    Assignee: Affera, Inc.
    Inventors: Doron Harlev, Andrew Miles Wallace, Luke Tsai
  • Patent number: 11751937
    Abstract: An ablation catheter having a deformable tip is disclosed herein. In some implementations, the ablation catheter includes a catheter body and a deformable tip secured to the catheter body. In these and other implementations, the catheter body can include a fluid delivery lumen. In these and other implementations, the deformable tip includes one or more valves that are configured to open in response to deformation of the deformable tip. In these and still other implementations, the ablation catheter is configured to permit liquid communication between an interior of the deformable tip and an exterior of the deformable tip. In some implementations, RF energy is transmitted from the interior of the deformable tip to the exterior of the deformable tip via liquid exiting the deformable tip.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: September 12, 2023
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Ian Matthew Collier
  • Patent number: 11728026
    Abstract: Systems and methods of the present disclosure are directed to controlling the build of a three-dimensional model of a cardiac chamber. More specifically, the systems and methods of the present disclosure can be used to rewind a portion of a construction of a three-dimensional model of the cardiac chamber.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: August 15, 2023
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Geoffrey Peter Wright
  • Patent number: 11553962
    Abstract: Devices, systems, and methods for treating cardiac arrhythmia are disclosed herein. In some embodiments, devices, systems, and methods disclosed herein deliver interrogating energy to tissue at a position on a wall of an anatomical structure of a patient. If the devices, systems, and methods disclosed herein detect a change in electrical activity of the anatomical structure in response to the interrogating energy, the devices, systems, and methods disclosed herein can apply irreversible therapy to the tissue. In some embodiments, the change in electrical activity corresponds to slowing or termination of a detected arrhythmia.
    Type: Grant
    Filed: January 20, 2021
    Date of Patent: January 17, 2023
    Assignee: Affera, Inc.
    Inventors: Doron Harlev, Paul B. Hultz
  • Patent number: 11490958
    Abstract: Devices, systems, and methods of the present disclosure are directed to controlling distribution of electrical energy moving from an ablation electrode at a treatment site within a patient to a plurality of return electrodes on skin of the patient. Control over the distribution of electrical energy moving from the ablation electrode to the plurality of return electrodes can reduce or eliminate the need for manual intervention (e.g., repositioning the plurality of return electrodes on the skin of the patient, repositioning the patient, etc.) to achieve a suitable distribution of the electrical energy. Additionally, or alternatively, the devices, systems, and methods of the present disclosure can respond rapidly and automatically to changes in distribution of the electrical energy to reduce the likelihood and magnitude of inadvertent changes in the distribution of electrical energy over the course of a medical procedure.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: November 8, 2022
    Assignee: Affera, Inc.
    Inventors: Doron Harlev, Ilya Bystryak, Alexander Shrabstein, Yanko K. Sheiretov, Joseph Harlev, Paul B. Hultz
  • Patent number: 11471216
    Abstract: Devices, systems, and methods of the present disclosure can overcome physical constraints associated with catheter introduction to facilitate the use of a catheter with a large distal portion as part of a medical procedure benefiting from such a large distal portion, such as, for example, cardiac ablation. More specifically, devices, systems, and methods of the present disclosure can compress an expandable tip of a catheter from an expanded state to a compressed state along a tapered surface of an insertion sleeve for advancement of the expandable tip into vasculature of a patient. The tapered surface of the insertion sleeve can, for example, apply compressive forces at an angle against the advancing expandable tip. As compared to other approaches to the application of compressive force to an expandable tip, compressing the expandable tip using an angled force can reduce the likelihood of unintended deformation of the expandable tip.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: October 18, 2022
    Assignee: Affera, Inc.
    Inventors: Doron Harlev, Andrew Miles Wallace, Luke Tsai, Ian Matthew Collier
  • Patent number: D963163
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: September 6, 2022
    Assignee: Affera, Inc.
    Inventors: Doron Harlev, Andrew Miles Wallace
  • Patent number: D1014762
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: February 13, 2024
    Assignee: AFFERA, INC.
    Inventors: Doron Harlev, Paul Brian Hultz, Andrew Miles Wallace