Abstract: The invention relates to a polypeptide comprising a variant of a protein of the Sac7d family that specifically binds to the human leptin receptor and is able to trigger the crossing of the intestinal barrier, in particular of biologicals associated with it.
Type:
Application
Filed:
December 5, 2022
Publication date:
April 30, 2026
Applicant:
AFFILOGIC
Inventors:
Simon HUET, Anne CHEVREL, Mathieu CINIER, Olivier KITTEN, Solène MASLOH, Leonardo SCAPOZZA, Magali ZEISSER-LABOUÈBE
Abstract: The invention relates to proteins having multi-specific binding abilities by fusion of an OB-fold variant, in particular from the Sac7d family, to the light or heavy chain of an antibody.
Type:
Application
Filed:
February 7, 2024
Publication date:
July 4, 2024
Applicant:
AFFILOGIC
Inventors:
Olivier KITTEN, Mathieu CINIER, Simon HUET
Abstract: The invention relates to proteins having multi-specific binding abilities by fusion of an OB-fold variant, in particular from the Sac7d family, to the light or heavy chain of an antibody.
Type:
Grant
Filed:
November 13, 2018
Date of Patent:
March 19, 2024
Assignee:
AFFILOGIC
Inventors:
Olivier Kitten, Mathieu Cinier, Simon Huet