Patents Assigned to Affinergy, LLC
  • Patent number: 9279810
    Abstract: Cell binding peptides are provided for binding to cells including urothelial and thyroid follicular cells. The peptides are useful for detection and diagnosis of cancer including bladder and thyroid cancer. A device and method for using the device for capturing cells is provided, the device includes a support having attached cell binding peptide. The support can be a slide and the device can be used for detection and diagnosis of cancer including bladder and thyroid cancer. A kit is provided with instructions for capturing cells and a support with attached cell binding peptide for detection and diagnosis of bladder and thyroid cancer.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: March 8, 2016
    Assignee: Affinergy, LLC
    Inventors: William David Culp, Martyn Kerry Darby, Dalia Isolda Juzumiene, Magdalena Krajewska, Natalia Lygina, Juhua Morrison, Shrikumar Ambujakshan Nair, William Bourchier Siesser, Danuta Wronska
  • Patent number: 8779089
    Abstract: Compositions and methods for tissue repair are provided including cell binding peptides and growth factor binding peptides. The cell binding peptides bind to one or more of stem cells, fibroblasts, or endothelial cells. The growth factor binding peptides include platelet derived growth factor (PDGF) binding peptides and growth differentiation factor (GDF) binding peptides. The tissue for repair includes tendon, muscle, connective tissue, ligament, cardiac tissue, vascular tissue, or dermis. Implantable devices for tissue repair are provided to which the cell and growth factor binding peptides are attached, such as acellular extracellular matrix having attached binding peptide.
    Type: Grant
    Filed: November 18, 2010
    Date of Patent: July 15, 2014
    Assignee: Affinergy, LLC
    Inventors: Isaac Gilliam Sanford, Michelle Steffen Jansen, Paul Theodore Hamilton, Jonathan Allen Hodges, Shrikumar Ambujakshan Nair, Yuchen Chen, Martyn Kerry Darby, Hanne Gron, Ganesan Sathya
  • Patent number: 8691946
    Abstract: Compositions and methods for tissue repair are provided including cell binding peptides and growth factor binding peptides. The cell binding peptides bind to one or more of stem cells, fibroblasts, or endothelial cells. The growth factor binding peptides include platelet derived growth factor (PDGF) binding peptides and growth differentiation factor (GDF) binding peptides. The tissue for repair includes tendon, muscle, connective tissue, ligament, cardiac tissue, vascular tissue, or dermis. Implantable devices for tissue repair are provided to which the cell and growth factor binding peptides are attached, such as acellular extracellular matrix having attached binding peptide.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: April 8, 2014
    Assignee: Affinergy, LLC
    Inventors: Isaac Gilliam Sanford, Martyn Kerry Darby, Jonathan Allen Hodges, Shrikumar Ambujakshan Nair, Yuchen Chen, Paul Theodore Hamilton, Ganesan Sathya, Hanne Gron, Michelle Steffen Jansen
  • Publication number: 20140079753
    Abstract: Compositions and methods for tissue repair are provided including cell binding peptides and BMP binding peptides. The cell binding peptides bind to one or more of stem cells and fibroblasts. The tissue for repair includes bone, tendon, muscle, connective tissue, ligament, cardiac tissue, bladder tissue, or dermis. Implantable devices for tissue repair are provided to which the cell and/or BMP binding peptides are attached, such as acellular extracellular matrix having attached binding peptide and bone graft material comprising a ceramic.
    Type: Application
    Filed: November 18, 2013
    Publication date: March 20, 2014
    Applicant: Affinergy, LLC
    Inventors: Martyn Kerry Darby, Dalia Isolda Juzumiene, Isaac Gilliam Sanford, Jonathan Allen Hodges, Shrikumar Ambujakshan Nair
  • Patent number: 8637455
    Abstract: The presently disclosed subject matter relates to peptides having binding affinity for glycopeptide antibiotics and methods and compositions for delivering glycopeptide antibiotic to the surface of medical devices. The peptide compositions can comprise a peptide having binding affinity for a surface material of a medical device that is coupled to the peptide having binding affinity for glycopeptide antibiotic. Also provided are methods of applying the peptide compositions to a medical device by contacting the peptide compositions with a surface of the medical device. In addition, kits are provided comprising the peptide compositions.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: January 28, 2014
    Assignees: Affinergy, LLC, DePuy Synthes Products, LLC
    Inventors: Martyn K. Darby, Isaac G. Sanford, R. Edward Benson, Hanne Gron, Paul T. Hamilton, Shrikumar A. Nair, Doug Buechter, Elliott Gruskin