Patents Assigned to Affymatrix, Inc
  • Computer software products for nucleic acid hybridization analysis
    Patent number: 6996475
    Abstract: Methods and computer software products are provided for analyzing gene expression data. In one embodiment, multiple probes are used to detect a single transcript. The hybridization intensities of each probe is adjusted by dividing the intensities by the affinities of the probes. The minimal adjusted hybridization intensity may be used as the measurement of the gene expression.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: February 7, 2006
    Assignee: Affymatrix, Inc
    Inventor: David Balaban
  • End-complementary polymerase reaction
    Patent number: 6489146
    Abstract: The present invention is directed to a process for amplifying and detecting any target nucleic acid sequence contained in a nucleic acid or mixture thereof and for assembling large polynucleotides from component polynucleotides, each involving generating concatemers formed by PCR amplification of overlapping fragments.
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: December 3, 2002
    Assignees: Glaxo Group Limited, Affymatrix, Inc.
    Inventors: Willem P.C. Stemmer, Robert J. Lipshutz