Abstract: The invention relates to a pharmaceutical composition in the form of an aqueous solution, preferably a syrup, containing inosine pranobex and zinc gluconate, characterised in that it contains a sweetener selected from the group of disaccharides, preferably sucrose or/and from the group of polyols, preferably maltitol, a solubilizer from the group of hydroxy alcohols or mixtures thereof, preferably propylene glycol, glycerol, preservatives selected from the group of parahydroxybenzoic acid esters and mixtures thereof, preferably methyl parahydroxybenzoate, propyl parahydroxybenzoate, a sweetener, preferably sodium saccharine or sucralose, and pH regulators in the range from 5.7 to 12.0 preferably aroma, and a method of preparation thereof.
Type:
Grant
Filed:
June 21, 2018
Date of Patent:
October 5, 2021
Assignee:
AFLOFARM FARMACJA POLSKA SP. Z O. O.
Inventors:
Hanna Wahl, Marek Dąbrowa, Anna Ostrowska, Malgorzata Kowalska - Parteka, Jaroslaw Pasiński, Arkadiusz Madejczyk
Abstract: The subject of the present invention is solid dosage form containing cytisine and ancillary substances characterised in that it contains from 0.1% to 5% micronised cytisine, wherein all molecules have a diameter less than from 10 ???, corn starch from 40% to 60%, preferably 99.9% particles sized from 5 ??? to 25 ???, macrocrystalline cellulose in an amount from 40% to 60%, preferably the particle size is: 99% below 38 ???, wherein the mass ratio of ancillary substances to the active ingredient is from 1:19 to 1:999 and is in the form of a hard capsule as well as a method of obtaining it.
Type:
Grant
Filed:
November 19, 2013
Date of Patent:
July 12, 2016
Assignee:
Aflofarm Farmacja Polska Sp. z o.o
Inventors:
Hanna Wahl, Marek Dabrowa, Piotr Kulazinski