Patents Assigned to AGI THERAPEUTICS PLC
  • Publication number: 20110301245
    Abstract: Methods comprising administering compositions comprising therapeutically effective amounts of the (R)-isomer of 2-(3,4-dimethoxyphenol)-2-isopropyl-6-azaheptanitril, a derivative thereof, or a pharmaceutically acceptable salt thereof, wherein the composition treats or prevents at least one condition having serotonin transporter activity in a subject in need thereof, and releases the (R)-isomer of 2-(3,4-dimethoxyphenol)-2-isopropyl-6-azaheptanitril, a derivative thereof, or a pharmaceutically acceptable salt thereof to exhibit an activity on the serotonin transporter.
    Type: Application
    Filed: August 4, 2010
    Publication date: December 8, 2011
    Applicant: AGI THERAPEUTICS, PLC
    Inventor: John DEVANE
  • Publication number: 20090214599
    Abstract: Pharmaceutical formulation comprising at least one proton pump inhibitor structured and arranged to provide an initial pH-dependent delayed release, and a pH-dependent extended release of the at least one proton pump inhibitor.
    Type: Application
    Filed: February 21, 2008
    Publication date: August 27, 2009
    Applicant: AGI THERAPEUTICS PLC
    Inventors: John DEVANE, David YOUNG
  • Publication number: 20090062242
    Abstract: Methods and compositions for treating a condition involving gastrointestinal symptoms comprising administering to a patient in need of such treatment an effective amount of a P-glycoprotein substrate, wherein the P-glycoprotein substrate is a compound exhibiting an efflux inhibition ratio (EIR) of greater than or equal to 0.4, wherein the P-glycoprotein substrate is administered in a manner to minimize bioavailability.
    Type: Application
    Filed: August 27, 2008
    Publication date: March 5, 2009
    Applicant: AGI Therapeutics plc
    Inventor: John G. DEVANE