Abstract: A method and computer program providing for substantially automated CAD/CAM design and manufacture of custom workholding fixtures used to locate and secure workpieces on which work, such as, for example, machining, welding, or assembly, is to be performed, wherein computer models of support structures and locating and clamping devices, including dimensions and mounting geometries associated therewith, facilitate development and testing of a workholding concept, production of fixture drawings, and generation and formatting of a corresponding control program for controlling a CNC or CAM machine for manufacturing the fixture.