Abstract: HIV protease inhibitors inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds can be prepared by the novel methods of the present invention using the novel inventive intermediates.
Type:
Grant
Filed:
February 19, 1999
Date of Patent:
September 12, 2000
Assignees:
Agouron Phramaceuticals, Inc., Japan Tobacco, Inc.
Inventors:
Srinivasan Babu, Bennett C. Borer, Travis P. Remarchuk, Robert J. Szendroi, Kathleen R. Whitten, Juliette K. Busse, Kim F. Albizati