Patents Assigned to AgraQuest, Inc.
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Patent number: 6060051Abstract: The present invention relates to a novel antibiotic-producing and metabolite-producing Bacillus subtilis strain that exhibits insecticidal, antifungal and antibacterial activity. The supernatant of this novel strain contains effective insecticidal, antifungal and antibacterial agents. Also included in the invention is a solvent extractable, small molecular weight (<10,000 daltons) corn rootworm-active metabolite produced in the supernatant. Also included in the invention are methods of protecting or treating plants from fungal and bacterial infections and corn rootworm infestations comprising the step of applying to the plant an effective amount of the antibiotic/metabolite-producing novel Bacillus subtilis strain, the antibiotic/metabolite produced by the novel Bacillus subtilis strain or a combination thereof, optionally further comprising another antibiotic-producing bacterial strain and/or a chemical pesticide.Type: GrantFiled: May 8, 1998Date of Patent: May 9, 2000Assignee: AgraQuest, Inc.Inventors: Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jimenez, Randy Jay McCoy, Pamela Gail Marrone, Jimmy Ensio Orjala
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Patent number: 6027723Abstract: A novel pesticidal metabolite-producing Rhodococcus globerulus strain is provided. In addition, a supernatant of the novel strains with pesticidal activity is provided. A solvent-extractable metabolite produced by the novel strain of Rhodococcus globerulus with pesticidal activity against corn rootworms is provided. Also included are methods for protecting or treating plants from corn rootworm infestations comprising the step of applying to the plant an effective amount of the novel Rhodococcus globerulus strain, the metabolite produced by the novel strain or a combination thereof, optionally, further comprising applying another pesticidal metabolite-producing bacterial strain and/or a chemical pesticide.Type: GrantFiled: August 22, 1997Date of Patent: February 22, 2000Assignee: AgraQuest, Inc.Inventors: Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jimenez, Pamela Gail Marrone
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Patent number: 6015553Abstract: A novel strain of Bacillus subtilis is provided that produces a metabolite that exhibits pesticidal activity. Also included in the invention is a solvent extractable and water soluble, large molecular weight (>10,000 daltons) metabolite produced by the novel strain of Bacillus subtilis that exhibits pesticidal activity against corn rootworms, other insects and nematodes. Also included in the invention are methods of protecting or treating plants from corn rootworm, other insect and nematode infestations comprising applying to the plant an effective amount of the novel Bacillus strain, a supernatant obtained from a whole broth culture of the novel strain, the metabolite produced by the novel Bacillus strain, a composition comprising the novel strain or a combination thereof, optionally further comprising applying at least one additional biological or chemical pesticide.Type: GrantFiled: August 22, 1997Date of Patent: January 18, 2000Assignee: AgraQuest, Inc.Inventors: James John Germida, Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jimenez, Pamela Gail Marrone
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Patent number: 6001637Abstract: A novel pesticidal metabolite-producing Bacillus pumilus strain is provided. In addition, a supernatant of the novel strain with pesticidal activity is provided. A solvent-extractable, small molecular weight (<10,000 daltons) metabolite produced by the novel strain of Bacillus pumilus with pesticidal activity against corn rootworm, beet armyworm and nematodes is provided. Also included are methods for protecting or treating plants from corn rootworm, nematode and beet armyworm infestations comprising the step of applying to the plant an effective amount of the novel Bacillus pumilus strain, the metabolite produced by the novel strain or a combination thereof, optionally, further comprising applying another pesticidal metabolite-producing bacterial strain and/or a chemical pesticide.Type: GrantFiled: August 22, 1997Date of Patent: December 14, 1999Assignee: AgraQuest, Inc.Inventors: Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jimenez, Pamela Gail Marrone
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Patent number: 5929113Abstract: This invention provides a method for repelling biting insects such as mosquitoes, ticks, and biting flies by topically applying to the skin of a subject emu oil, fractions of emu oil obtained by flash chromatography or a composition comprising emu oil or active fractions thereof and at least one other insect repellent such as citronella, DEET or saponin. Also provided are compositions for repelling biting insects comprising diluted fractions of emu oil, and compositions comprising emu oil or active fractions thereof and at least one other insect repellent such as citronella, DEET or saponin.Type: GrantFiled: June 16, 1997Date of Patent: July 27, 1999Assignee: AgraQuest, Inc.Inventors: Denise C. Manker, Pamela Gail Marrone, Stephen Judd
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Patent number: 5919447Abstract: The present invention provides a Bacillus thuringiensis strain that exhibits broad antifungal and antibacterial activity. The invention also provides the use of the Bacillus thuringiensis strain or the antibiotic produced by the strain for control of a broad range of fungal and bacterial plant pathogens.Type: GrantFiled: January 22, 1997Date of Patent: July 6, 1999Assignee: Agraquest, Inc.Inventors: Pamela Gail Marrone, Sherry D. Heins, Denise C. Manker, Desmond R. Jimenez, Chris N. Chilcott, Peter Wigley, Andrew Broadwell
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Patent number: 5906818Abstract: A novel pesticidal metabolite-producing B. mycoides strain is provided. In addition, a supernatant of the novel strain with pesticidal activity is provided. A water-soluble, small molecular weight (<10,000 daltons) metabolite produced by the novel strain of Bacillus mycoides with pesticidal activity against corn rootworm is provided. Also included are methods for protecting or treating plants from corn rootworm infestations comprising the step of applying to the plant an effective amount of the novel Bacillus mycoides strain, the metabolite produced by the novel strain or a combination thereof, optionally, further comprising applying another pesticidal metabolite-producing bacterial strain and/or a chemical pesticide.Type: GrantFiled: August 22, 1997Date of Patent: May 25, 1999Assignee: AgraQuest, Inc.Inventors: Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jimenez, Pamela Gail Marrone
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Patent number: 5869042Abstract: Above-ground fungal and bacterial infections of plants are treated by applying to the plants an antibiotic-producing Bacillus sp. strain ATCC 55608, 55609, 53522 and/or zwittermicin-A antibiotic therefrom. The above-ground infections treated can be caused by Phytophthora infestans, Botrytis cinerea, Pseudomonas syringae, Alternaria solani, Plasmopara viticola, Uncinula necator, Puccinia recondita f.sp. Tritici, Staganospora nodorum, Monilinia fructicola or Erwinia herticola. The Bacillus sp. and/or antibiotic when applied can be in the form of a whole culture broth, an antibiotic-containing supernatant, a powder, granules, a concentrate, an aqueous suspension or a microencapsulated formulation.Type: GrantFiled: November 22, 1996Date of Patent: February 9, 1999Assignee: AgraQuest, Inc.Inventors: Pamela Gail Marrone, Sherry D. Heins, Desmond R. Jimenez
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Patent number: 5801196Abstract: This invention provides a method for repelling biting insects such as mosquitoes by topically applying to the skin of a subject fractions of emu oil obtained by flash chromatography. Also provided are methods for repelling biting insects by topically applying diluted fractions of emu oil. The invention also provides a compound useful in repelling biting insects having the NMR spectrum of FIG. 3, that is ultra violet light sensitive and is reactive to vanillin/sulfuric acid. Also provided are compounds useful in repelling biting insects having the NMR spectrum of FIG. 4, that is not ultra violet light sensitive and is not reactive to vanillin/sulfuric acid.Type: GrantFiled: April 4, 1997Date of Patent: September 1, 1998Assignees: AgraQuest, Inc., P.E. ZogenInventors: Denise C. Manker, Pamela Gail Marrone, Stephen Judd
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Patent number: 5733544Abstract: The present invention relates to a newly discovered Bacillus sp. strain which exhibits pesticidal activity. The supernatant of cultures of this novel isolate are also effective pesticidal agents. Also provided are methods of using the novel strain or supernatant for treatment or prevention of disease in plants or animals.Type: GrantFiled: November 18, 1996Date of Patent: March 31, 1998Assignees: University of Saskatchewan, Agraquest, Inc.Inventors: Pamela Gail Marrone, Denise C. Manker, Sherry D. Heins, Desmond R. Jimenez, James J. Germida
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Patent number: 5691191Abstract: A nutrient medium used in fermentation for increasing the yield of cells or microorganisms is provided. The formulation provided increases the yield of the fungus Lagenidium giganteum two- to three-fold over known media. The medium contains peptone, yeast extract, Proflo.RTM. cottonseed flour, glucose, palm oil, cholesterol, CaCl.sub.2 and MgCl.sub.2.Type: GrantFiled: March 15, 1996Date of Patent: November 25, 1997Assignee: AgraQuest, Inc.Inventors: Sherry Darlene Heins, Duane Douglas Ewing, Pamela Gail Marrone
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Patent number: 5677338Abstract: This invention provides a method for repelling biting insects such as mosquitoes by topically applying to the skin of a subject fractions of emu oil obtained by flash chromatography. Also provided are methods for repelling biting insects by topically applying diluted fractions of emu oil. The invention also provides a compound useful in repelling biting insects having the NMR spectrum of FIG. 3, that is ultra violet light sensitive and is reactive to vanillin/sulfuric acid. Also provided are compounds useful in repelling biting insects having the NMR spectrum of FIG. 4, that is not ultra violet light sensitive and is not reactive to vanillin/sulfuric acid.Type: GrantFiled: November 18, 1996Date of Patent: October 14, 1997Assignee: AgraQuest, Inc.Inventors: Denise C. Manker, Pamela Gail Marrone, Stephen Judd
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Patent number: 5645831Abstract: The present invention relates to a newly isolated Bacillus thuringiensis strain which exhibits insecticidal activity. The supernatant of cultures of this novel strain is also an effective insecticidal agents. Also included in the invention are the novel B. thuringiensis isolate, its supernatant and a solvent extract of the supernatant which are specifically active against corn rootworm but not against beet armyworm, nematodes or flies. These strains and supernatants may be used to treat plants infected with susceptible organisms.Type: GrantFiled: March 22, 1996Date of Patent: July 8, 1997Assignees: BioDiscovery New Zealand Ltd., AgraQuest, Inc.Inventors: Chris N. Chilcott, Peter Wigley, Andrew Broadwell, Sherry Darlene Heins, Pamela Gail Marrone
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Patent number: 5626882Abstract: This invention provides a method for repelling biting insects such as mosquitoes by topically applying emu oil to the skin.Type: GrantFiled: March 15, 1996Date of Patent: May 6, 1997Assignees: AgraQuest, Inc., P.E. ZoogenInventors: Pamela G. Marrone, Stephen A. Judd