Abstract: The invention provides a composition for attenuating neovascularization and treating malignancies, including a pharmaceutically effective amount of a compound having a formula:
wherein:
R1 is a number of the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl and lower alkoxy,
R2 is a member of the group consisting of hydroxy, acetoxy, and lower alkoxy, and
R3 is a member of the group consisting of hydrogen and lower alkenoxy carbonyl, as active ingredient therein, in combination with a pharmaceutically acceptable carrier.
Type:
Grant
Filed:
January 10, 2000
Date of Patent:
July 16, 2002
Assignees:
Madasit Medical Research Services & Development Co.,
Ltd., Agricultural Research Organization-Ministry of
Agricultural
Inventors:
Mark Pines, Israel Vlodavsky, Arnon Nagler