Patents Assigned to Agriculture Victoria Services Pty Ltd.
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Patent number: 9840695Abstract: Genetic constructs capable of manipulating fructan biosynthesis in photosynthetic cells of a plant, said genetic constructs include a promoter operatively linked to a nucleic acid encoding a bacterial FT enzyme. These constructs can be used in modification of fructan biosynthesis in plants and, more particularly, for manipulating fructan biosynthesis in photosynthetic cells. The constructs can also be used for increasing plant biomass and, more particularly, for enhancing biomass yield and/or yield stability, including shoot and/or root growth in a plant, and for enhancing the productivity of biochemical pathways.Type: GrantFiled: March 12, 2010Date of Patent: December 12, 2017Assignee: Agriculture Victoria Services Pty LtdInventors: German Spangenberg, Aidyn Mouradov, Timothy Ivor Sawbridge
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Patent number: 9839676Abstract: The invention provides a method for treating cancer in a subject or a method of inducing an anti-tumour effect including reducing tumour volume, inhibiting or slowing tumour growth, inhibiting tumour progression, altering the metabolic activity of a tumour, inducing quiescence of a tumour, inhibiting or reducing metastasis, inhibiting or reducing tumour invasiveness, reducing tumour weight, reducing tumour neovascularisation, improving time to disease progression (TDP) and/or improving survival, the method comprising administering to the subject an effective amount of angiogenin or an angiogenin agonist.Type: GrantFiled: May 10, 2013Date of Patent: December 12, 2017Assignees: Murray Goulburn Co-Operative Co., Limited, AGRICULTURE VICTORIA SERVICES PTY LTDInventors: Peter Hobman, Andrew Brown
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Patent number: 9789168Abstract: The invention provides a method of treating a disorder characterized by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: GrantFiled: July 28, 2015Date of Patent: October 17, 2017Assignees: AGRICULTURE VICTORIA SERVICES PTY LTD, Murray Goulburn Co-Operative Co., LimitedInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman, Andrew Brown, Michelle Rowney
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Patent number: 9752130Abstract: The present invention relates to nucleic acid fragments encoding amino acid sequences for flavonoid biosynthetic enzymes in plants, and the use thereof for the modification of, for example, flavonoid biosynthesis in plants, and more specifically the modification of the content of condensed tannins. In particularly preferred embodiments, the invention relates to the combinatorial expression of chalcone synthase (CHS) and/or dihydroflavonol 4-reductase (BAN) and/or leucoanthocyanidine reductase (LAR) in plants to modify, for example, flavonoid biosynthesis or more specifically the content of condensed tannins.Type: GrantFiled: December 6, 2011Date of Patent: September 5, 2017Assignees: Agriculture Victoria Services PTY LTD, AgResearch LimitedInventors: German Spangenberg, Michael Emmerling, Jason Simmonds, Amanda Winkworth, Stephen Panter
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Publication number: 20170191075Abstract: The present invention relates to the modification of lignin biosynthesis in plants, to enzymes involved in the lignin biosynthetic pathway and nucleic acids encoding such enzymes and, more particularly, to methods of modifying lignin biosynthesis via sense suppression and to related nucleic acids and constructs.Type: ApplicationFiled: January 12, 2017Publication date: July 6, 2017Applicants: Dairy Australia Limited, Agriculture Victoria Services Pty LtdInventors: German Spangenberg, Angela Jane Lidgett, Robyn Louise Heath, Russell Leigh McInnes, Damian Paul Lynch, Ulrik Peter John, Aidyn Mouradov, Megan Elizabeth Griffith
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Publication number: 20170118943Abstract: The present invention relates to a method for identifying and/or characterising an endophyte strain, said method including providing a plurality of samples of endophytes, subjecting said endophytes to genetic analysis, subjecting said endophytes to metabolic analysis and selecting endophytes having a desired genetic and metabolic profile. The present invention also relates to novel endophytes having a desired toxin profile wherein the endophyte produces significantly less toxic alkaloids compared with a control endophyte such as standard toxic (ST) endophyte; and/or significantly more alkaloids conferring beneficial properties compared with a control endophyte such as ST endophyte. The present invention also relates to endophyte variants having a desired genetic and metabolic profile, wherein said endophyte variants possess genetic and/or metabolic characteristics that result in a beneficial phenotype in a plant harbouring or otherwise associated with the endophyte variant.Type: ApplicationFiled: November 23, 2016Publication date: May 4, 2017Applicant: Agriculture Victoria Services PTY LTDInventors: German Spangenberg, Kathryn Michaela Guthridge, John White Forster, Timothy Ivor Sawbridge, Emma Jane Isobel Ludlow, Jatinder Kaur, Simone Jane Rochfort, Maia Andrea Rabinovich, Piyumi Ekanayake
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Patent number: 9567599Abstract: The present invention relates to nucleic acids encoding flavonoid biosynthetic enzymes, flavonoid-regulating transcription factors and a flavonoid-specific membrane transporter in plants, and the use thereof for the modification of flavonoid biosynthesis in plants. The present invention also relates to constructs and vectors including such nucleic acids, and related polypeptides. More particularly, the protein involved in flavonoid biosynthesis is selected from the group consisting of TRANSPARENT TESTA 12 (TT12), TRANSPARENT TESTA GLABRA 1 (TTG1), TRANSPARENT TESTA 2 (TT2), TRANSPARENT TESTA 8 (TT8), Ieucoanthocyanidin dioxygenase (LDOX), cinnamate-4-hydroxylase (C4H), 4-coumaroyl:CoA-ligase (4CL); and functionally active fragments and variants thereof.Type: GrantFiled: August 26, 2013Date of Patent: February 14, 2017Assignee: Agriculture Victoria Services PTY LTDInventors: Aidyn Mouradov, German Spangenberg
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Patent number: 9523089Abstract: The present invention relates to nucleic acids and nucleic acid fragments encoding amino acid sequences for flavonoid biosynthetic enzymes in plants, and the use thereof for the modification of flavonoid biosynthesis in plants. More particularly, the flavonoid biosynthetic enzyme is selected from the group consisting of chalcone isomerase (CHI), chalcone synthase (CHS), chalcone reductase (CHR), dihydroflavonol 4-reductase (DFR), leucoanthocyanidin reductase (LCR), flavonoid 3?,5? hydrolase (F3?5?H), flavanone 3-hydroxylase (F3H), flavonoid 3?-hydroxylase (F3?H), phenylalanine ammonia-olyase (PAL) and vestitone reductase (VR), and functionally active fragments and variants thereof.Type: GrantFiled: September 13, 2013Date of Patent: December 20, 2016Assignees: Agriculture Victoria Services Pty LTD, AgResearch LimitedInventors: German Spangenberg, Timothy Ivor Sawbridge, Eng-Kok Ong, Michael Emmerling
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Patent number: 9394527Abstract: The present invention relates to nucleic acid fragments encoding amino acid sequences for organic acid biosynthetic enzymes in plants, and the use thereof for the modification of, for example, organic acid biosynthesis and secretion in plants. In particularly preferred embodiments, the invention relates to the combinatorial expression of citrate synthase (CS) and/or malate dehydrogenase (MDH) and/or phosphoenolpyruvate carboxylase (PEPC) in plants to modify, for example, organic acid synthesis and secretion.Type: GrantFiled: March 8, 2011Date of Patent: July 19, 2016Assignee: AGRICULTURE VICTORIA SERVICES PTY LTDInventors: German Spangenberg, Michael Emmerling, Eng Kok Ong, Ramiro Mendez, Stephen Panter, Marcel Labandera
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Publication number: 20160186205Abstract: The present invention relates to methods for controlling hybridization in plants and producing hybrid plants. The present invention also relates to nucleic acids encoding amino acid sequences for self-incompatibility (SI) proteins in plants, and the use thereof for the manipulation of SI, including seed production, in plants, particularly of the Poaceae family. The present invention also relates to kits, compositions, constructs and vectors including such nucleic acids, and related polypeptides, regulatory elements and methods. The present invention also relates to expression of self-gamete recognition genes in plants and to related nucleic acids, constructs, molecular markers and methods.Type: ApplicationFiled: February 19, 2014Publication date: June 30, 2016Applicants: Agriculture Victoria Services Pty Ltd, Dairy Futures Limited, Dairy Australia LimitedInventors: Hiroshi Shinozuka, Noel Cogan, John White Forster, German Carlos Spangenberg, Nicola Patron, Yidong Ran, Luke Pembleton
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Patent number: 9247766Abstract: The invention provides methods for enriching a milk extract for angiogenin, such methods involving separation by size, charge or immunoaffinity. The invention also provides the angiogenin enriched extract produced by the methods and provides them in pharmaceutical and neutraceutical compositions and foods for treating a variety of diseases or disorders that can be treated by angiogenin.Type: GrantFiled: May 14, 2009Date of Patent: February 2, 2016Assignees: Murray Goulburn Co-Operative Co., Limited, Agriculture Victoria Services Pty Ltd.Inventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman, Andrew Brown
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Patent number: 9222096Abstract: The present invention provides substantially purified or isolated fungi of Nodulisporium spp. or Ascocoryne spp., plants infected with said fungi, organic compounds produced by said fungi, and related nucleic acids, polypeptides and methods.Type: GrantFiled: May 22, 2012Date of Patent: December 29, 2015Assignee: Agriculture Victoria Services PTY LTDInventors: German Carlos Spangenberg, Timothy Ivor Sawbridge, Simone Jane Rochfort, Scott W. Mattner, Ross C. Mann
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Patent number: 9119818Abstract: The invention provides a method of treating a disorder characterized by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: GrantFiled: May 14, 2009Date of Patent: September 1, 2015Assignees: AGRICULTURE VICTORIA SERVICES PTY LTD, Murray Goulburn Co-Operative Co., LimitedInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman
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Publication number: 20150156982Abstract: The present invention relates to new methods of selecting and breeding organisms, in particular organisms which exhibit symbiotic behaviour with symbionts, and to new organisms and symbiota developed thereby, such as plant or grass and endophyte symbiota. Multiple symbionts are deployed in multiple organisms and selected for improved symbiotic compatibility and performance early in the breeding process. Methods include producing improved organisms from germplasm, by inoculating host organism germplasm libraries with symbionts selected from symbiont libraries and selecting improved host organisms exhibiting desired symbiota characteristics, and selection of organism-symbiont associations with a desired genetic and metabolic profile by metagenomic analysis of nucleic acid libraries from an organism or organism-symbiont association.Type: ApplicationFiled: May 29, 2013Publication date: June 11, 2015Applicant: Agriculture Victoria Services Pty LtdInventors: German Carlos Spangenberg, John White Forster, Noel Cogan, Yidong Ran, John Gregory Mason, Timothy Ivor Sawbridge, Ben Hayes, Matthew James Hayden, Kathryn Michaela Guthridge, Simone Jane Rochfort, Ben Cocks, Hans Dieter Daetwyler
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Publication number: 20150150952Abstract: The invention provides a method for treating cachexia, weakness, fatigue, and/or fever in a subject, the method comprising administering to the subject an effective amount of angiogenin or an angiogenin agonist. The method is particularly applicable to the prevention or treatment of cancer cachexia.Type: ApplicationFiled: May 10, 2013Publication date: June 4, 2015Applicants: Murray Goulburn Co-Operative Co., Ltd., Agriculture Victoria Services Pty Ltd.Inventors: Paul Lewandowski, Ross Crittenden, Peter Hobman
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Publication number: 20150150161Abstract: The present invention relates to new methods of selecting and breeding organisms, in particular organisms which exhibit symbiotic behaviour with symbionts such as fungal endophytes or epiphytes or bacterial microbiome in plants, and to new organisms and symbiota developed thereby. More particularly, the present invention provides artificial seeds comprising symbiota, and methods for preparing and using such artificial seeds, as well as plants, plant seeds and other plant parts derived from artificial seeds or symbiont-containing plants of the present invention.Type: ApplicationFiled: May 29, 2013Publication date: May 28, 2015Applicant: Agriculture Victoria Services PTY LTDInventors: German Carlos Spangenberg, Yidong Ran, John Gregory Mason, Kathryn Michaela Guthridge
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Patent number: 8921653Abstract: The present invention relates to the modification of lignin biosynthesis in plants and, more particularly, to enzymes involved in the lignin biosynthetic pathway and nucleic acids encoding such enzymes.Type: GrantFiled: May 12, 2008Date of Patent: December 30, 2014Assignees: Agriculture Victoria Services Pty Ltd, Dairy Australia LimitedInventors: German Spangenberg, Angela Jane Lidgett, Robyn Louise Heath, Russell Leigh McInnes, Damian Paul Lynch, Ulrik John, Aidyn Mouradov
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Patent number: 8889951Abstract: The application discloses non-naturally occurring barley plants with increased resistance to herbicides, particularly imidazolinone herbicides. The imidazolinone resistance is conferred by mutant acetohydroxy acid synthase (AHAS), more particularly by AHAS with a SER653 mutation. Also disclosed are the barley seeds per se, an isolated nucleic acid incorporating the nucleic acid sequence conferring imidazolinone resistance, a method of inhibiting weed growth in the vicinity of a barley plant, an a method of growing a barley crop. Seeds have been deposited at NCIMB.Type: GrantFiled: May 6, 2009Date of Patent: November 18, 2014Assignee: Agriculture Victoria Services Pty LtdInventors: Michael Materne, Christopher Pittock, David Moody
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Patent number: 8829277Abstract: The present invention relates to methods of manipulating senescence in plants. The invention also relates to vectors useful in such methods, transformed plants with modified senescence characteristics and plant cells, seeds and other parts of such plants.Type: GrantFiled: March 8, 2013Date of Patent: September 9, 2014Assignees: Agriculture Victoria Services Pty Ltd., La Trobe UniversityInventors: German Spangenberg, Carl McDonald Ramage, Melissa Ann Palviainen, Roger W. Parish, Joshua Heazlewood
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Patent number: 8809624Abstract: The present invention relates to nucleic acids or nucleic acid fragments encoding amino acid sequences for fatty acid biosynthesis enzymes in plants, and the use thereof for the modification of, for example, fatty acid biosynthesis in plants. In particular, the present invention relates to nucleic acids or nucleic acid fragments encoding amino acid sequences of diacylglycerol acyltransferase enzymes.Type: GrantFiled: January 11, 2011Date of Patent: August 19, 2014Assignees: AgResearch Limited, Agriculture Victoria Services Pty LtdInventors: Gregory Thomas Bryan, Margaret Fiona Burling, Nicholas John Roberts, Alana Jean Trollope, Derek Ross Woodfield