Patents Assigned to AgriMetis, LLC
  • Publication number: 20200385767
    Abstract: Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.
    Type: Application
    Filed: August 19, 2020
    Publication date: December 10, 2020
    Applicant: AgriMetis, LLC
    Inventors: Brian Michael Green, Michelle Lorraine Gradley
  • Patent number: 10781465
    Abstract: Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: September 22, 2020
    Assignee: AgriMetis, LLC
    Inventors: Brian Michael Green, Michelle Lorraine Gradley, Annette Alcasabas
  • Patent number: 10717756
    Abstract: Compositions and methods for the production of derivatives of spinosyns are provided. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and/or nematodes and are useful in the agricultural and animal health markets.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: July 21, 2020
    Assignee: AgriMetis, LLC
    Inventors: Andrew Calabrese, Brian Michael Green, David R. Spring, Jerome Yves Cassayre, Pasquale N. Confalone
  • Patent number: 10711026
    Abstract: Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of spinosyn A to provide an additional ring system. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and/or nematodes and are useful in the agricultural and animal health markets.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: July 14, 2020
    Assignee: AgriMetis, LLC
    Inventors: Andrew Calabrese, Brian Michael Green, David R. Spring, Jerome Yves Cassayre, Pasquale N. Confalone
  • Publication number: 20200181179
    Abstract: Compositions and methods for isolating L-glufosinate from a composition comprising L-glufosinate and glutamate are provided. The method comprises converting the glutamate to pyroglutamate followed by the isolation of L-glufosinate from the pyroglutamate and other components of the composition to obtain substantially purified L-glufosinate. The composition comprising L-glufosinate and glutamate is subjected to an elevated temperature for a sufficient time to allow for the conversion of glutamate to pyroglutamate, followed by the isolation of L-glufosinate from the pyroglutamate and other components of the composition to obtain substantially purified L-glufosinate. The glutamate alternatively may be converted to pyroglutamate by enzymatic conversion. The purified L-glufosinate is present in a final composition at a concentration of 90% or greater of the sum of L-glufosinate, glutamate, and pyroglutamate.
    Type: Application
    Filed: July 17, 2018
    Publication date: June 11, 2020
    Applicant: AGRIMETIS, LLC
    Inventors: Stephen Craig Fields, Matthew Richard Oberholzer, Brian Michael Green, Samir Kulkarni, Jennifer Nelson, Patricia Andres
  • Publication number: 20200148716
    Abstract: Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include those functionalized on the C-5,6 double bond to provide an aziridine ring system. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and nematodes and are useful in the agricultural and animal health markets.
    Type: Application
    Filed: January 10, 2020
    Publication date: May 14, 2020
    Applicant: AgriMetis, LLC
    Inventor: Andrew A. Calabrese
  • Patent number: 10570166
    Abstract: Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of the spinosyn. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and nematodes and are useful in the agricultural and animal health markets.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: February 25, 2020
    Assignee: AgriMetis, LLC
    Inventor: Andrew Calabrese
  • Patent number: 10570165
    Abstract: Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include those functionalized on the C-5,6 double bond to provide an aziridine ring system. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and nematodes and are useful in the agricultural and animal health markets.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: February 25, 2020
    Assignee: AgriMetis, LLC
    Inventor: Andrew A. Calabrese
  • Publication number: 20190185889
    Abstract: Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.
    Type: Application
    Filed: February 27, 2019
    Publication date: June 20, 2019
    Applicant: AgriMetis, LLC
    Inventors: Brian Michael Green, Michelle Lorraine Gradley, Annette Alcasabas
  • Patent number: 10260078
    Abstract: Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: April 16, 2019
    Assignee: AgriMetis, LLC
    Inventors: Brian Michael Green, Michelle Lorraine Gradley
  • Publication number: 20190071464
    Abstract: Compositions and methods for the production of derivatives of spinosyns are provided. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and/or nematodes and are useful in the agricultural and animal health markets.
    Type: Application
    Filed: September 1, 2016
    Publication date: March 7, 2019
    Applicant: AGRIMETIS, LLC
    Inventors: Andrew Calabrese, Brian Michael Green, David R. Spring, Jerome Yves Cassayre, Pasquale N. Confalone
  • Publication number: 20180291053
    Abstract: Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include those functionalized on the C-5,6 double bond to provide an aziridine ring system. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and nematodes and are useful in the agricultural and animal health markets.
    Type: Application
    Filed: January 3, 2018
    Publication date: October 11, 2018
    Applicant: AgriMetis, LLC
    Inventor: Andrew A. Calabrese
  • Publication number: 20180251487
    Abstract: Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of the spinosyn. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and nematodes and are useful in the agricultural and animal health markets.
    Type: Application
    Filed: September 1, 2016
    Publication date: September 6, 2018
    Applicant: AGRIMETIS, LLC
    Inventor: Andrew Calabrese
  • Publication number: 20180030487
    Abstract: Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.
    Type: Application
    Filed: October 18, 2017
    Publication date: February 1, 2018
    Applicant: AgriMetis, LLC
    Inventors: Brian Michael Green, Michelle Lorraine Gradley
  • Patent number: 9834802
    Abstract: Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: December 5, 2017
    Assignee: AgriMetis, LLC
    Inventors: Brian Michael Green, Michelle Lorraine Gradley
  • Publication number: 20170253897
    Abstract: Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.
    Type: Application
    Filed: February 28, 2017
    Publication date: September 7, 2017
    Applicant: AgriMetis, LLC
    Inventors: Brian Michael Green, Michelle Lorraine Gradley