Abstract: The present disclosure is generally directed to an agricultural formulation comprising an anucleated minicells and an anucleated cell-based platforms for encapsulation and scalable delivery of biologically active compounds. Disclosed herein are compositions for the stable and targeted delivery of biologically active compounds within achromosomal and/or anucleated cells onto and/or into a target cell. The present disclosure also provides methods of improving encapsulation and retention of biologically active compounds in achromosomal and/or anucleated cells and delivering biologically active compounds into a target cell.
Type:
Grant
Filed:
December 26, 2023
Date of Patent:
January 14, 2025
Assignee:
AgroSpheres, Inc.
Inventors:
Ameer Hamza Shakeel, Zachery George Davis, Joseph Thomas Frank, Sepehr Zomorodi, Payam Pourtaheri
Abstract: The present disclosure is generally directed to an anucleated cell-based platforms for encapsulation and delivery of agricultural compounds. Disclosed herein are compositions for the stable and targeted delivery of agricultural compounds within achromosomal and/or anucleated cells. The present disclosure also provides methods of improving encapsulation and retention of agricultural compounds in achromosomal and/or anucleated cells.
Type:
Grant
Filed:
March 28, 2023
Date of Patent:
April 30, 2024
Assignee:
AgroSpheres, Inc.
Inventors:
Ameer Hamza Shakeel, Sepehr Zomorodi, Joseph Thomas Frank, Zachery George Davis, Payam Pourtaheri
Abstract: The present disclosure is generally directed to an agricultural formulation comprising an anucleated minicells and an anucleated cell-based platforms for encapsulation and scalable delivery of biologically active compounds. Disclosed herein are compositions for the stable and targeted delivery of biologically active compounds within achromosomal and/or anucleated cells onto and/or into a target cell. The present disclosure also provides methods of improving encapsulation and retention of biologically active compounds in achromosomal and/or anucleated cells and delivering biologically active compounds into a target cell.
Type:
Application
Filed:
December 26, 2023
Publication date:
April 25, 2024
Applicant:
AgroSpheres, Inc.
Inventors:
Ameer Hamza SHAKEEL, Zachery George DAVIS, Joseph Thomas FRANK, Sepehr ZOMORODI, Payam POURTAHERI
Abstract: The present disclosure is generally directed to an agricultural formulation comprising an anucleated minicells and an anucleated cell-based platforms for encapsulation and scalable delivery of biologically active compounds. Disclosed herein are compositions for the stable and targeted delivery of biologically active compounds within achromosomal and/or anucleated cells onto and/or into a target cell. The present disclosure also provides methods of improving encapsulation and retention of biologically active compounds in achromosomal and/or anucleated cells and delivering biologically active compounds into a target cell.
Type:
Grant
Filed:
September 25, 2018
Date of Patent:
November 14, 2023
Assignee:
AgroSpheres, Inc.
Inventors:
Ameer Hamza Shakeel, Zachery George Davis, Joseph Thomas Frank, Sepehr Zomorodi, Payam Pourtaheri
Abstract: The present disclosure is generally directed to an anucleated cell-based platforms for encapsulation and delivery of agricultural compounds. Disclosed herein are compositions for the stable and targeted delivery of agricultural compounds within achromosomal and/or anucleated cells. The present disclosure also provides methods of improving encapsulation and retention of agricultural compounds in achromosomal and/or anucleated cells.
Type:
Grant
Filed:
April 30, 2018
Date of Patent:
May 16, 2023
Assignee:
AgroSpheres, Inc.
Inventors:
Ameer Hamza Shakeel, Sepehr Zomorodi, Joseph Thomas Frank, Zachery George Davis, Payam Pourtaheri
Abstract: The present disclosure relates to compositions of immobilized enzymes on the surface of achromosomal and/or anucleate cells and uses thereof. In particular, the present disclosure provides genetically engineered minicells with enzymes self-assembled on their surface. The immobilized enzymes on the surface of achromosomal and/or anucleate minicells, has agricultural, industrial, and environmental applications due to their improved stability durability and, reusability. Also, provided are methods for producing and purifying enzyme-immobilized minicells.
Type:
Grant
Filed:
April 30, 2018
Date of Patent:
April 11, 2023
Assignee:
AgroSpheres, Inc.
Inventors:
Ameer Hamza Shakeel, Zachery George Davis, Joseph Thomas Frank, Sepehr Zomorodi, Payam Pourtaheri