Patents Assigned to Ahio University
  • Compositions that bind antiterminator RNA and assay for screening for such compositions
    Patent number: 7550511
    Abstract: Compounds that are selective binding agents specific for RNA secondary and tertiary structures and a fluorescence assay for detecting the binding of small molecules to T-box antiterminator model mRNAs. The compounds include novel tri-substituted oxazolidinones and amino alcohols. The assay provides fluorescently labeled model mRNAs that include conserved sequence information typical of antiterminator bulge regions found in the mRNA of T-box gene regulatory systems.
    Type: Grant
    Filed: October 24, 2005
    Date of Patent: June 23, 2009
    Assignee: Ahio University
    Inventors: Jennifer V. Hines, Stephen C. Bergmeier, Tina M. Henkin, Frank J. Grundy