Abstract: A tissue detection system includes a probe having a body defining a distal end portion for positioning in contact with or close proximity to tissue. The probe includes an emission optical fiber extending from an input end through the probe body to an output end at the distal end portion of the probe body, and a detection optical fiber extending from an output end through the probe body to an input end at the distal end portion of the probe body. An emitter is coupled to the input end of the emission optical fiber and a detector is coupled to the output end of the detection optical fiber. One or more optical elements is disposed at the detector filter out electromagnetic radiation received from the detection optical fiber below a pre-determined wavelength threshold or outside of a pre-determined wavelength range.

Abstract: A tissue detection system and methods for use thereof are provided. The tissue detection system facilitates stimulating fluorescence via illumination in an area or areas of interest in the human body, detecting non-visible or not easily visible areas of interest subject to such stimulation, and identifying these areas of interest efficiently. The tissue detection system can employ a probe for facilitating illumination/stimulation of a tissue of interest, at least one emitter for generating radiation applied to the tissue of interest, and at least one detector for capturing radiation for the fluorescing tissues of interest.

Abstract: A tissue detection system includes a probe having a body and an emission optical fiber extending from an input end through the probe body to an output end at a distal end portion of the probe body. The emission optical fiber defines a Numerical Aperture (NA). The tissue detection system further includes an emitter configured to output electromagnetic radiation and an optical coupler optically coupling the emitter with the input end of the emission optical fiber such that, in response to receiving the output from the emitter, electromagnetic radiation is input to the input end of the emission optical fiber. The optical coupler modifies the electromagnetic radiation such that the electromagnetic radiation input to the input end of the emission optical fiber defines an NA about equal to or less than the NA of the emission optical fiber.

Abstract: Devices and methods for visibly highlighting areas of a region including an imager configured to image the region with a sensitivity to at least one of wavelength, light level, or contrast greater than the human eye, an overlay element configured to visibly highlight areas of the region and registered to the imager to produce alignment of imaged features with highlighted features at the same location on the region, and at least one of a controller executing a program or logic configured to process acquired images from the imager to identify areas of the region determined not visible to the human eye, and control the overlay element to visibly highlight those areas on the region.

Abstract: A tissue detection system and methods for use thereof are provided. The tissue detection system facilitates stimulating fluorescence via illumination in an area or areas of interest in the human body, detecting non-visible or not easily visible areas of interest subject to such stimulation, and identifying these areas of interest efficiently. The tissue detection system can employ a probe for facilitating illumination/stimulation of a tissue of interest, at least one emitter for generating radiation applied to the tissue of interest, and at least one detector for capturing radiation for the fluorescing tissues of interest.

Abstract: Devices and methods for visibly highlighting areas of a region including an imager configured to image the region with a sensitivity to at least one of wavelength, light level, or contrast greater than the human eye, an overlay element configured to visibly highlight areas of the region and registered to the imager to produce alignment of imaged features with highlighted features at the same location on the region, and at least one of a controller executing a program or logic configured to process acquired images from the imager to identify areas of the region determined not visible to the human eye, and control the overlay element to visibly highlight those areas on the region.