Patents Assigned to AI2 Limited
  • TREATMENT OF FUNGAL AND/OR PROTIST INFECTIONS
    Publication number: 20150190462
    Abstract: The present invention relates to the use of a polypeptides, comprising repeats of a peptide derived from a Heparan Sulphate Proteoglycan (HSPG) receptor binding region of an apolipoprotein, for treating or preventing a fungal and/or protist infection. The invention further relates to the use of such peptides for treating or preventing the contamination of surfaces or objects with such peptides.
    Type: Application
    Filed: November 14, 2014
    Publication date: July 9, 2015
    Applicant: Ai2 Limited
    Inventor: Curtis Dobson
  • Treatment of fungal and/or protist infections
    Patent number: 8916516
    Abstract: The present invention relates to the use of a polypeptides, comprising repeats of a peptide derived from a Heparan Sulphate Proteoglycan (HSPG) receptor binding region of an apolipoprotein, for treating or preventing a fungal and/or protist infection. The invention further relates to the use of such peptides for treating or preventing the contamination of surfaces or objects with such peptides.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: December 23, 2014
    Assignee: AI2 Limited
    Inventor: Curtis Dobson
  • Treatment of bacterial infections
    Patent number: 8524861
    Abstract: The invention relates to polypeptides, comprising repeats of peptides derived from apolipoproteins, which exhibit antibacterial activity and to nucleic acids encoding the same. The invention further provides the use of such polypeptides, derivatives, analogues or nucleic acids as medicaments, and also their use in methods of preventing or treating bacterial infection or objects and surfaces. The invention further extends to objects, such as contact lenses, coated with the polypeptides.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: September 3, 2013
    Assignee: AI2 Limited
    Inventors: Curtis Dobson, Keith Alan Crutcher
  • TREATMENT OF VIRAL INFECTIONS
    Publication number: 20130150288
    Abstract: The present invention concerns polypeptides derived from a tandem repeat of apoE141-149 and their uses as medicaments. The peptides may comprise the tandem repeat, and truncations thereof, for which at least one Leucine (L) is replaced by an amino acid with a side chain comprising at least 4 carbon atoms and at least one Nitrogen atom. Such peptides are useful for preventing or treating viral infections.
    Type: Application
    Filed: July 16, 2012
    Publication date: June 13, 2013
    Applicant: AI2 LIMITED
    Inventor: Curtis Dobson
  • TREATMENT OF FUNGAL AND/OR PROTIST INFECTIONS
    Publication number: 20120258907
    Abstract: The present invention relates to the use of a polypeptides, comprising repeats of a peptide derived from a Heparan Sulphate Proteoglycan (HSPG) receptor binding region of an apolipoprotein, for treating or preventing a fungal and/or protist infection. The invention further relates to the use of such peptides for treating or preventing the contamination of surfaces or objects with such peptides.
    Type: Application
    Filed: December 22, 2011
    Publication date: October 11, 2012
    Applicant: AI2 LIMITED
    Inventor: Curtis Dobson
  • Treatment of viral infections
    Patent number: 8017579
    Abstract: The present invention relates to polypeptides, and derivatives or analogues thereof, comprising a tandem repeat of apolipoprotein B, or a truncation thereof, derived from an HSPG receptor binding region of apolipoprotein B. Such peptides are useful for treating or preventing the development of viral infections.
    Type: Grant
    Filed: December 20, 2004
    Date of Patent: September 13, 2011
    Assignee: Ai2 Limited
    Inventor: Curtis Dobson
  • TREATMENT OF VIRAL INFECTIONS
    Publication number: 20100221273
    Abstract: The present invention concerns polypeptides derived from a tandem repeat of apoE141-149 and their uses as medicaments. The peptides may comprise the tandem repeat, and truncations thereof, for which at least one Leucine (L) is replaced by an amino acid with a side chain comprising at least 4 carbon atoms and at least one Nitrogen atom. Such peptides are useful for preventing or treating viral infections.
    Type: Application
    Filed: February 9, 2010
    Publication date: September 2, 2010
    Applicant: AI2 LIMITED
    Inventor: Curtis Dobson
  • Antiviral polypeptides comprising tandem repeats of APOE 141-149 and variants thereof
    Patent number: 7691382
    Abstract: The present invention concerns polypeptides derived from a tandem repeat of apoE141-149 and their uses as medicaments. The peptides may comprise the tandem repeat, and truncations thereof, for which at least one Leucine (L) is replaced by an amino acid with a side chain comprising at least 4 carbon atoms and at least one Nitrogen atom. Such peptides are useful for preventing or treating viral infections.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: April 6, 2010
    Assignee: AI2 Limited
    Inventor: Curtis Dobson
  • Treatment of Fungal and/or Protist Infections
    Publication number: 20080207508
    Abstract: The present invention relates to the use of a polypeptides, comprising repeats of a peptide derived from a Heparan Sulphate Proteoglycan (HSPG) receptor binding region of an apolipoprotein, for treating or preventing a fungal and/or protist infection. The invention further relates to the use of such peptides for treating or preventing the contamination of surfaces or objects with such peptides.
    Type: Application
    Filed: June 26, 2006
    Publication date: August 28, 2008
    Applicant: AI2 LIMITED
    Inventor: Curtis Dobson