Abstract: A method of treatment of a condition such as deep vein thrombosis, arterial insufficiency, lymphedema, pulmonary embolism, and pain includes use of a pneumatic compression wrap, pump, and medicament to provide compression on the body part of a patient and a pharmaceutical beneficial in treating the condition. Deep vein thrombosis, arterial insufficiency, lymphedema, pulmonary embolism, and pain can also be treated by an electrotherapy device utilizing a hydrogel patch containing a medicament. Apparatus and systems for performing the methods of treatment can be utilized.