Patents Assigned to AIMED BIO INC.
  • Benzoselenophene-based compound, pharmaceutical composition containing same, and antibody-drug conjugate
    Patent number: 11938115
    Abstract: The present disclosure relates to a benzoselenophene-based compound, a method of preparing the benzoselenophene-based compound, and a pharmaceutical composition and antibody-drug conjugate including the benzoselenophene-based compound.
    Type: Grant
    Filed: July 29, 2022
    Date of Patent: March 26, 2024
    Assignee: AIMED BIO INC.
    Inventors: Dongyeol Lim, Min Cheol Kim, Amol Mhetre, Do-Hyun Nam
  • Magnetic-based biopanning method through attachment of magnetic bead to cell
    Patent number: 11591718
    Abstract: The present invention relates to a method for screening an antibody or antigen-binding fragment thereof by using cells bearing magnetic beads and, more particularly, to a method for screening an antibody binding specifically to an antigen protein or an antigen-binding fragment thereof, in which cells having biotinylated phospholipids in the cell membranes thereof and a streptavidin-magnetic bead complex fused to the surfaces thereof, and a magnetic-based system are utilized.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: February 28, 2023
    Assignee: AIMED BIO INC.
    Inventors: Do-Hyun Nam, Byeongkwi Min
  • Benzoselenophene-based compounds, pharmaceutical compositions and antibody-drug conjugates including the same
    Patent number: 11576896
    Abstract: The present disclosure relates to benzoselenophene-based compounds, method of preparing the benzoselenophene-based compounds, pharmaceutical compositions and antibody-drug conjugates including the benzoselenophene-based compounds.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: February 14, 2023
    Assignee: AIMED BIO INC.
    Inventors: Dongyeol Lim, Min Cheol Kim, Amol Mhetre, Do-Hyun Nam
  • Method for screening antibody using patient-derived tumor spheroids
    Patent number: 11199536
    Abstract: The present disclosure relates to a method of screening an antibody or an antigen-binding fragment thereof by use of patient-derived tumor spheroids, and more particularly to a method of screening an antibody or an antigen-binding fragment thereof, which binds specifically to an antigen, by use of patient-derived tumor spheroids containing the antigen.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: December 14, 2021
    Assignee: AIMED BIO INC.
    Inventor: Do-Hyun Nam
  • Anti-NRP1 antibody screening method
    Patent number: 11085930
    Abstract: The present disclosure relates to a method of screening an anti-NRP1 antibody or an antigen-binding fragment thereof by use of patient-derived tumor spheroids overexpressing NRP1 and an animal model comprising the same, and more particularly to a method of screening an antibody or an antigen-binding fragment thereof through in vitro and in vivo panning by use of a patient-derived tumor spheroid containing NRP1 and an animal model transplanted with the same, respectively.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: August 10, 2021
    Assignee: AIMED BIO INC.
    Inventors: Do-Hyun Nam, Jae Hyun Lee