Patents Assigned to AIMM Therapeutics B.V.
  • Means and methods for influencing the stability of antibody producing cells
    Patent number: 9127251
    Abstract: The invention provides a method for influencing the stability of an antibody producing cell, comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression product within said antibody producing cell. Stable antibody producing cells and cell lines are also provided, as well as methods for producing antibodies using such cells and/or cell lines.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: September 8, 2015
    Assignees: ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM, AIMM THERAPEUTICS B.V.
    Inventors: Hergen Spits, Ferenc A. Scheeren, Tim Beaumont, Sean A. Diehl
  • Means and methods for influencing the stability of cells
    Patent number: 9005974
    Abstract: The invention provides a method for influencing the stability of an antibody producing cell, comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression product within said antibody producing cell. Stable antibody producing cells and cell lines are also provided, as well as methods for producing antibodies using such cells and/or cell lines.
    Type: Grant
    Filed: December 9, 2005
    Date of Patent: April 14, 2015
    Assignees: Academish Medisch Centrum Bij de Universiteit van Amsterdam, AIMM Therapeutics B.V.
    Inventor: Hergen Spits
  • RSV G PROTEIN SPECIFIC ANTIBODIES
    Publication number: 20150004155
    Abstract: The disclosure relates to human isolated, synthetic or recombinant antibodies or functional parts thereof, specific for the RSV G protein. Antibodies specific for the RSV G protein are particularly suitable for counteracting RSV and symptoms, such as inflammation, resulting from an RSV infection. The disclosure further relates to the use of such RSV G-specific antibodies for diagnosis of an RSV infection and as a medicament and/or prophylactic agent for, at least in part, treating or alleviating symptoms of a Respiratory Syncytial Virus infection and/or a Respiratory Syncytial Virus related disorder.
    Type: Application
    Filed: November 16, 2012
    Publication date: January 1, 2015
    Applicant: AIMM THERAPEUTICS B.V.
    Inventors: Tim Beaumont, Etsuko Yasuda
  • GRAM-POSITIVE BACTERIA SPECIFIC BINDING COMPOUNDS
    Publication number: 20140235828
    Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
    Type: Application
    Filed: December 11, 2013
    Publication date: August 21, 2014
    Applicants: AIMM THERAPEUTICS B.V., GENENTECH, INC.
    Inventors: Tim BEAUMONT, Mark Jeroen KWAKKENBOS, Eric J. BROWN, John Hiroshi MORISAKI, Wouter L.W. HAZENBOS, Sanjeev MARIATHASAN, Kimberly KAJIHARA, Yi XIA
  • Gram-positive bacteria specific binding compounds
    Patent number: 8617556
    Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: December 31, 2013
    Assignees: Genentech, Inc., AIMM Therapeutics B.V.
    Inventors: Tim Beaumont, Mark Jeroen Kwakkenbos, Eric J. Brown, John Hiroshi Morisaki, Wouter L. W. Hazenbos, Sanjeev Mariathasan, Kimberly Kajihara, Yi Xia
  • MEANS AND METHODS FOR PRODUCING HIGH AFFINITY ANTIBODIES
    Publication number: 20130331552
    Abstract: Described are means and methods for producing high-affinity antibodies against an antigen of interest, using stable B-cell cultures.
    Type: Application
    Filed: December 2, 2011
    Publication date: December 12, 2013
    Applicant: AIMM Therapeutics B.V.
    Inventors: Tim Beaumont, Mark Jeroen Kwakkenbos, Hergen Spits, Adrianus Quirinus Bakker, Koen Wagner
  • RSV SPECIFIC BINDING MOLECULE
    Publication number: 20120070446
    Abstract: The invention provides antibodies and functional equivalents thereof which are capable of specifically binding RSV. Nucleic acid sequences encoding said antibody, as well as antibody producing cells and methods for producing said antibody are also provided.
    Type: Application
    Filed: October 5, 2010
    Publication date: March 22, 2012
    Applicant: AIMM THERAPEUTICS B.V.
    Inventors: TIM BEAUMONT, ADRIANUS Q. BAKKER, ETSUKO YASUDA
  • Means and Methods for Influencing the Stability of Cells
    Publication number: 20100093038
    Abstract: The invention provides a method for influencing the stability of an antibody producing cell, comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression product within said antibody producing cell. Stable antibody producing cells and cell lines are also provided, as well as methods for producing antibodies using such cells and/or cell lines.
    Type: Application
    Filed: December 9, 2005
    Publication date: April 15, 2010
    Applicants: Academisch Medisch Centrum bij de Universiteit van Amsterdam, AIMM Therapeutics B.V.
    Inventor: Hergen Spits