Abstract: Air purification devices are disclosed that cleanse air of germs and microbes through an oxidation process using an ultraviolet light source that causes a chemical reaction with a proximate catalyst-coated surface. The devices use a replaceable ionization cell folded into a core assembly and positioned around the ultraviolet light source. The ionization cell is coated with the reactive catalyst on at least an inner surface facing the light source and air is cleansed as it passes through the ionization cell. The devices provide safety mechanisms to protect against human exposure to the ultraviolet light.