Patents Assigned to Akita University
-
Publication number: 20150292037Abstract: The objective of the present invention is to provide a method and a means of rapidly and reliably detecting lymph node metastasis in cancer or the risk of lymph node metastasis. Specifically, the present invention provides a method and a rapid determination kit for detecting lymph node metastasis in cancer or its risk by identifying a certain genetic polymorphism of the human CRP gene, and it is clinically significant in determining the treatment strategy, because effective prediction/determination can be made regarding lymph node metastasis, which is an important phenomenon in cancer progression.Type: ApplicationFiled: June 24, 2015Publication date: October 15, 2015Applicant: NATIONAL UNIVERSITY CORPORATION AKITA UNIVERSITYInventors: Satoru MOTOYAMA, Masatomo MIURA, Junichi OGAWA
-
Patent number: 9125693Abstract: Provided are: a screw guide template, screw guide template system, and drilling method whereby a hole can be drilled in an accurate position of a member to be drilled, in an accurate direction; and a spinal fixation method whereby a spinal fixation screw can be inserted into an accurate position in an accurate direction. The screw guide template (20) comprises: a close-contact face (21) to be closely contacted to the member; and a through hole (22) having one opening (23a) on the close-contact face; the close-contact face has a shape in male-female relation with a surface shape (31) of the member including a portion (32) to be drilled; and when the close-contact face is closely contacted to the portion to be drilled, the opening and portion to be drilled overlap each other so that the through hole is coaxial with the hole to be drilled by the drilling means.Type: GrantFiled: May 30, 2011Date of Patent: September 8, 2015Assignees: AKITA UNIVERSITY, ONO & CO., LTD.Inventors: Taku Sugawara, Kazuo Mizoi, Naoki Higashiyama, Hidenori Ono, Hisayuki Sugiyama
-
Publication number: 20150233902Abstract: Acceleration and automation of immunohistochemical staining are achieved as follows: an automatic electric field immunohistochemical staining apparatus is configured to provided with a sample mounting unit, a solution supply unit, an electric field stifling unit, and a washing unit; the sample mounting unit on which a glass substrate with a tissue specimen fixed thereto is mounted and the electric field stirring unit that includes an upper electrode are operated in coordination to activate an antigen in the tissue specimen; the sample mounting unit and the solution supply unit containing various solutions are operated in coordination to supply a primary-antibody-containing solution to the tissue specimen; the sample mounting unit and the electric field stirring unit are operated in coordination to perform an antigen-antibody reaction of the antigen in the tissue specimen and a primary antibody; and the electric field stirring unit and the washing unit are operated in coordination.Type: ApplicationFiled: February 20, 2014Publication date: August 20, 2015Applicants: AKITA UNIVERSITY, GOVERNOR OF AKITA PREFECTUREInventors: Yoichi Akagami, Masami Kagaya, Ryuta Nakamura, Hiroshi Ikeda, Yoshihiro Minamiya, Hiroshi Nanjo
-
Patent number: 9096904Abstract: The objective of the present invention is to provide a method and a means of rapidly and reliably detecting lymph node metastasis in cancer or the risk of lymph node metastasis. Specifically, the present invention provides a method and a rapid determination kit for detecting lymph node metastasis in cancer or its risk by identifying a certain genetic polymorphism of the human CRP gene, and it is clinically significant in determining the treatment strategy, because effective prediction/determination can be made regarding lymph node metastasis, which is an important phenomenon in cancer progression.Type: GrantFiled: May 27, 2010Date of Patent: August 4, 2015Assignee: NATIONAL UNIVERSITY CORPORATION AKITA UNIVERSITYInventors: Satoru Motoyama, Masatomo Miura, Junichi Ogawa
-
Patent number: 8920535Abstract: A separation and recovery method that enables titanium and tungsten to be separated and recovered from a used DeNOx catalyst in high yield. Specifically, a method of separating and recovering metal elements that includes a first heating step of heating a DeNOx catalyst containing titanium, tungsten, vanadium and iron in a chlorine atmosphere, thereby removing the vanadium and the iron from the DeNOx catalyst, and a second heating step, performed after the first heating step, of heating the DeNOx catalyst in a chlorine atmosphere while the catalyst is exposed to a gas of a hydrocarbon compound (excluding CH4) or an oxygen-containing carbon compound, thereby volatilizing the tungsten and the titanium from the DeNOx catalyst, and recovering the tungsten and the titanium from the DeNOx catalyst.Type: GrantFiled: April 23, 2013Date of Patent: December 30, 2014Assignees: Mitsubishi Heavy Industries, Ltd., National University Corporation Akita UniversityInventors: Masashi Kiyosawa, Katsumi Nochi, Norihisa Kobayashi, Kozo Iida, Katsuyasu Sugawara, Yuuki Mochizuki
-
Patent number: 8891190Abstract: An electric field writing magnetic storage device including: a rotatable disk including a substrate and a magnetic recording film provided on a surface of the substrate, the magnetic recording film including at least one ferromagnetic and ferroelectric layer; a writing device writing information into the magnetic recording film by means of an electric field, the writing device including a writing electrode generating a dielectric flux between the writing electrode and the substrate by having electric potential to the substrate; and a writing circuit choosing one electric potential among plurality of electric potential level and applying the chosen one electric potential to the writing electrode in every operation of writing information, wherein the dielectric flux generated according to the electric potential applied to the writing electrode by the writing circuit magnetizes the ferromagnetic and ferroelectric layer in a specific direction.Type: GrantFiled: October 31, 2012Date of Patent: November 18, 2014Assignee: Akita UniversityInventors: Satoru Yoshimura, Hitoshi Saito
-
Patent number: 8801280Abstract: A temperature measuring method using a temperature probe in which a temperature-sensitive magnetic substance having an arbitrary Curie point is arranged in a portion to be measured. A magnetic field is generated from a magnetic field generation source disposed at a position away from the portion to be measured. A change of the magnetic flux vector of the magnetic field depending on the temperature of the temperature-sensitive magnetic substance is detected by a magnetic sensor to measure the temperature of the portion to be measured, thereby the temperature of the portion to be measured can be wirelessly measured from the position away from the portion to be measured and the reduction in size can be easy.Type: GrantFiled: January 9, 2009Date of Patent: August 12, 2014Assignee: Akita UniversityInventors: Noboru Yoshimura, Kazutaka Mitobe, Jun-ichi Ogawa, Hajime Saito
-
Publication number: 20140218016Abstract: A magnetic profile measuring device which scans a space where an alternating-current magnetic field exists by a magnetized probe on a tip of a driven cantilever, detects vibration of the cantilever, and generates an image of magnetic field distribution of the space, the device including: the cantilever having the probe equipped on the tip thereof; a driver driving the cantilever; a vibration sensor detecting vibration of the probe wherein the driven vibration of the cantilever is frequency-modulated by the alternating-current magnetic field; a demodulator demodulating from a detection signal of the vibration sensor a magnetic signal corresponding to an alternating-current magnetic field; a scanning mechanism; a data storage storing an initial data for each coordinate of the space; a modified data generator recalling the initial data from the data storage and generating a plurality of data by modifying the phase of the initial data; and an image display device.Type: ApplicationFiled: September 25, 2012Publication date: August 7, 2014Applicant: Akita UniversityInventors: Hitoshi Saito, Satoru Yoshimura
-
Publication number: 20140182731Abstract: A drainpipe comprising a concentrating flow path to concentrate flow of fluid on an inner wall of the pipe, which makes it possible to inhibit freezing of the fluid hydrodynamically without providing heat energy from outside, to thereby prevent blockage of the pipe.Type: ApplicationFiled: December 26, 2012Publication date: July 3, 2014Applicants: Akita University, Yoshida Anny Co., Ltd.Inventors: Yoshimi Komatsu, Yoshihiro Yoshida
-
Publication number: 20140179677Abstract: A novel therapeutic agent for ectopic pregnancy having a therapeutic effect for ectopic pregnancy, especially unruptured ectopic pregnancy, and a novel method of screening a therapeutic agent for ectopic pregnancy are disclosed. The therapeutic agent for ectopic pregnancy contains as an effective ingredient a suppressor of brain-derived neurotrophic factor (BDNF) and/or of brain-derived neurotrophic factor receptor (TrkB). The method of screening a therapeutic agent for ectopic pregnancy includes measuring the kinase activity of TrkB in the presence of a test substance and the kinase activity of TrkB in the absence of the test substance; and selecting the test substance which decreases the kinase activity of TrkB.Type: ApplicationFiled: December 28, 2011Publication date: June 26, 2014Applicant: AKITA UNIVERSITYInventor: Kazuhiro Kawamura
-
Publication number: 20140155939Abstract: To provide a spine immobilization tool that can control the movement of the spine with improved safety as a spine immobilization tool that includes a first covering portion, a second covering portion, and a joint portion. The first covering portion covers at least a part of a vertebral arch of a vertebra at a head-side among the adjacent vertebrae, and thus can be fixed to the vertebra. The second covering portion covers at least a part of a vertebral arch of a vertebra at a buttock side among the adjacent vertebrae, and thus can be fixed to the vertebra. The joint portion couples the first covering portion and the second covering portion together while allowing changing relative positions of the first covering portion and the second covering portion.Type: ApplicationFiled: June 20, 2012Publication date: June 5, 2014Applicant: AKITA UNIVERSITYInventor: Taku Sugawara
-
Patent number: 8621658Abstract: A magnetic-field-observation device and method for measuring magnetic force near a magnetic material specimen's surface with high resolution and detecting the polarity of the magnetic pole of specimen's surface.Type: GrantFiled: September 5, 2011Date of Patent: December 31, 2013Assignee: Akita UniversityInventors: Hitoshi Saito, Satoru Yoshimura
-
Patent number: 8557020Abstract: A compound represented by General Formula (1) below, where R denotes a C1-C10 hydrocarbon group, Z denotes any one of a sulfide group, a sulfinyl group and a sulfonyl group, and n denotes an integer of 4 to 8 is described. A method for extracting metals and a metal recovery method using a metal extractant comprising the compound represented by General Formula (1) are also described.Type: GrantFiled: March 2, 2011Date of Patent: October 15, 2013Assignees: Dowa Holdings Co., Ltd., Akita UniversityInventors: Fumio Hamada, Chun-Bin Li, Yoshihiko Kondo
-
Patent number: 8500846Abstract: The present invention is to provide a novel rare metal extractant containing a cyclic phenol sulfide derivative of the formula (1) and a method for extractive separation of rare metal(s) using the rare metal extractant with high efficiency.Type: GrantFiled: February 10, 2009Date of Patent: August 6, 2013Assignee: Akita UniversityInventors: Yoshihiko Kondo, Chun-bin Li, Manabu Yamada, Fumio Hamada
-
Patent number: 8490209Abstract: Provided are a surface state measuring device which can measure an alternating force of an arbitrary frequency and which is excellent in spatial resolution, and a surface state measuring method using the device. This surface state measuring device measures the surface state of a sample by detecting the modulation of the oscillation of a probe arranged above the sample. The measuring device comprises: a cantilever having a probe near a free end; an excitation mechanism for exciting the cantilever; a scanning mechanism for making the probe scan the sample by moving the probe and the sample relative to each other; and alternating force generator for generating an alternating force of an arbitrary frequency in a space; and a modulation measuring mechanism for measuring the degree of frequency modulation or amplitude modulation of the oscillations of the probe, which are generated by the alternating force.Type: GrantFiled: August 9, 2010Date of Patent: July 16, 2013Assignee: Akita UniversityInventor: Hitoshi Saito
-
Publication number: 20130174302Abstract: A magnetic-field-observation device and method for measuring magnetic force near a magnetic material specimen's surface with high resolution and detecting the polarity of the magnetic pole of specimen's surface.Type: ApplicationFiled: September 5, 2011Publication date: July 4, 2013Applicant: AKITA UNIVERSITYInventors: Hitoshi Saito, Satoru Yoshimura
-
Patent number: 8470478Abstract: A solid electrolyte which is made of a material having high biocompatibility and which is capable of conducting a large electric current while performing a rectifying function; and an electrochemical element employing the same. The solid electrolyte is formed by stacking a first layer containing an acidic amino acid and a second layer containing a basic amino acid; and the electrochemical element is formed by disposing the solid electrolyte between a positive electrode and a negative electrode.Type: GrantFiled: February 4, 2011Date of Patent: June 25, 2013Assignee: Akita UniversityInventor: Yutaka Tsujiuchi
-
Publication number: 20130116700Abstract: Provided are: a screw guide template, screw guide template system, and drilling method whereby a hole can be drilled in an accurate position of a member to be drilled, in an accurate direction; and a spinal fixation method whereby a spinal fixation screw can be inserted into an accurate position in an accurate direction. The screw guide template (20) comprises: a close-contact face (21) to be closely contacted to the member; and a through hole (22) having one opening (23a) on the close-contact face; the close-contact face has a shape in male-female relation with a surface shape (31) of the member including a portion (32) to be drilled; and when the close-contact face is closely contacted to the portion to be drilled, the opening and portion to be drilled overlap each other so that the through hole is coaxial with the hole to be drilled by the drilling means.Type: ApplicationFiled: May 30, 2011Publication date: May 9, 2013Applicants: ONO&CO., LTD., AKITA UNIVERSITYInventors: Taku Sugawara, Kazuo Mizoi, Naoki Higashiyama, Hidenori Ono, Hisayuki Sugiyama
-
Publication number: 20130034748Abstract: The present invention provides: a method of producing, at low temperature, a magnetic recording medium comprising an L10FePt thin film which is highly (001)-oriented and highly L10-ordered; and a magnetic recording medium comprising an L10FePt thin film that can be obtained by this method. In the production method of a magnetic recording medium (10), a thin film formation step S1 of forming a thin film 2 containing an FePt alloy and an oxide of metal having a melting point of 100° C. or more and 500° C. or less is carried out; an annealing step S2 of annealing the thin film 2 to a predetermined temperature is carried out; thereby a magnetic recording layer 2? containing the FePt alloy having a L10-ordered structure and the oxide of metal is formed. The magnetic recording medium can be obtained by this production method.Type: ApplicationFiled: April 21, 2011Publication date: February 7, 2013Applicant: AKITA UNIVERSITYInventors: Shunji Ishio, Shun Shibata
-
Publication number: 20120301793Abstract: The present invention provides: a solid electrolyte which is made of a material having high biocompatibility and which is capable of conducting a large electric current while performing a rectifying function; and an electrochemical element employing the same. The solid electrolyte is formed by stacking a first layer containing an acidic amino acid and a second layer containing a basic amino acid; and the electrochemical element is formed by disposing the solid electrolyte between a positive electrode and a negative electrode.Type: ApplicationFiled: February 4, 2011Publication date: November 29, 2012Applicant: AKITA UNIVERSITYInventor: Yutaka Tsujiuchi