Abstract: The present invention relates to Rucaparib and/or Talazoparib and/or Veliparib and/or Olaparib, and/or AZD 2461, or a pharmaceutically acceptable salt thereof, for use in the treatment of impaired skin wound healing in a subject, an in vitro method for identifying a subject suffering from impaired skin wound healing to be responsive to the treatment with Rucaparib and/or Talazoparib and/or Veliparib and/or Olaparib and/or AZD 2461, and kits and kits-of-part related thereto.
Type:
Grant
Filed:
April 24, 2018
Date of Patent:
May 2, 2023
Assignee:
AKRIBES BIOMEDICAL GMBH
Inventors:
Barbara Wolff-Winiski, Anton Stütz, Petra Dörfler
Abstract: The present invention relates to an in vitro method for identifying a skin wound in an individual as being a non-healing skin wound or healing skin wound, in vitro methods for monitoring the healing of a skin wound in an individual, methods for screening for compounds suitable for modulating skin wound healing, as well as kits related thereto.
Type:
Grant
Filed:
October 23, 2017
Date of Patent:
February 14, 2023
Assignee:
AKRIBES BIOMEDICAL GMBH
Inventors:
Barbara Wolff-Winiski, Anton Stütz, Petra Dörfler
Abstract: The present invention relates to a Selective Glucocorticoid Receptor Modulator (SEGRM), or a pharmaceutically acceptable salt thereof, for use in the treatment of impaired skin wound healing in a subject, an in vitro method for identifying a subject suffering from impaired skin wound healing to be responsive to the treatment with a Selective Glucocorticoid Receptor Modulator (SEGRM), or a pharmaceutically acceptable salt thereof, and kits and kits-of-part related thereto.
Type:
Application
Filed:
July 20, 2021
Publication date:
February 17, 2022
Applicant:
AKRIBES BIOMEDICAL GMBH
Inventors:
Barbara WOLFF-WINISKI, Anton STÜTZ, Nicole SCHÖFMANN, Petra DÖRFLER
Abstract: The present invention relates to a PARP inhibitor in combination with a glucocorticoid and/or ascorbic acid and/or a protein growth factor for the treatment of impaired wound healing.
Type:
Application
Filed:
April 24, 2018
Publication date:
April 30, 2020
Applicant:
AKRIBES BIOMEDICAL GMBH
Inventors:
BARBARA WOLFF-WINISKI, ANTON STÜTZ, PETRA DÖRFLER
Abstract: The present invention relates to Rucaparib and/or Talazoparib and/or Veliparib and/or Olaparib, and/or AZD 2461, or a pharmaceutically acceptable salt thereof, for use in the treatment of impaired skin wound healing in a subject, an in vitro method for identifying a subject suffering from impaired skin wound healing to be responsive to the treatment with Rucaparib and/or Talazoparib and/or Veliparib and/or Olaparib and/or AZD 2461, and kits and kits-of-part related thereto.
Type:
Application
Filed:
April 24, 2018
Publication date:
March 12, 2020
Applicant:
AKRIBES BIOMEDICAL GMBH
Inventors:
BARBARA WOLFF-WINISKI, ANTON STÜTZ, PETRA DÖRFLER