Abstract: A method for supplying a multicomponent fluid thermosetting resin gluing system in which a first fluid component is brought to flow in a first stream, and a second fluid component is brought to flow in a second stream, wherein the second stream is brought to encircle the first stream. A device for carrying out the method comprising a first body (10) provided with outlet conduits (20,21,22); a second body (30) having as many outlet apertures (40,41,42) as there are outlet conduits of the first body; each conduit being introduced into one aperture. Use of the device for which the apertures in the second body shell are fitted with externally protruding outlet conduits having an outlet nozzle, each conduit introduced into the same aperture extending beyond the nozzle of the conduit fitted to the same aperture, for supplying a multicomponent fluid thermosetting resin gluing system according to the method.

Abstract: The invention relates to a compound having formula (I) wherein A is an optionally unsaturated 5- or 6-membered ring, which may comprise a heteroatom selected from N,O and S and which may be substituted with oxo or (1-6C) alkyl; R1, R2 and R3 are independently H, (1-6C) alkyl, (1-6C) alkoxy,(1-6C) alkoxy-(1-6C) alkyl, carbo(1-6C) alkoxy or halogen; X is O or S; and n is 1 or 2; or a pharmaceutically acceptable salt thereof, with the exception of 3-(naphth-1-yl-oxy)-pyrrolidin and 3-(5,6,7,8-tetrahydro-napth-1-yl-oxy)-pyrrolidin. The compounds of the invention have antidepressant activity and can be used in treating or preventing serotonin-related diseases.

Abstract: A process for the formation of a di(hydroxyalkylaryl) aryl phosphate is disclosed which comprises the reaction of an o-alkyl substituted aromatic diol, e.g., an o-alkyl substituted hydroquinone such as o-t-butylhydro-quinone, and monoaryl dihalophosphate, such as monophenyl dichlorophosphate. This process can, in particular, be used to make certain di(hydroxy-o-alkylphenyl) phenyl phosphate compounds, preferably those that are p-hydroxy, such as di(p-hydroxy-o-t-butylphenyl) phenyl phosphate.

Abstract: A paving system having a strike-off assembly and method of manufacture is provided that distributes paving material onto a road surface. The strike-off assembly comprises a screed assembly comprised in a guide frame. The screed assembly comprises a flexible screed having a first and second surface secured in a screed track. The screed assembly may be disposed behind a mobile paving system to regulate the amount of paving material distributed onto the road surface and to ensure a generally even distribution of paving material across the road surface. After the surface of the flexible screed has become worn or damaged from use, the screed assembly may be removed and reversed such that the second surface is employed to regulate and distribute paving material onto the road surface.

Abstract: This invention relates to methods for improving the therapeutic response of human patients with major depression by determining the apolipoprotein E genotype of a human patient and administering mirtazapine, in an amount effective to treat major depression, to those patients who are found to carry the gene for apolipoprotein E4. Also disclosed are methods for improving the therapeutic response of a human patient with major depression comprising administering mirtazapine, in an amount effective to treat major depression, to a human patient who is a carrier of the gene for apolipoprotein E4.

Abstract: The invention pertains to a pharmaceutical dosage unit, such as a tablet or a capsule, comprising an effective amount of tibolone (generally of from 0.1 to 10% by weight) and a starch-containing pharmaceutically acceptable carrier (also denoted as basic granulate), wherein the carrier contains of from 10 to 100% by weight of the starch. Thus a more stable tibolone formulation is obtained, allowing dry storage and lower doses of active ingredient.

Abstract: A process for manufacturing continuous polyester filament yarn for technical applications from a polymer over 90% of the chains of which are composed of ethylene terephthalate units, via a one-step spinning process, with the undrawn filaments having a crystallinity smaller than 16% and the yarn being wound at a rate larger than 6000 m/min. The yarn obtained in this fashion is particularly suitable for use as reinforcing material in rubber articles, notably as reinforcing material in pneumatic tires for cars.

Abstract: A process for the determination of the presence or concentration of a polyepitopic antigen in a specimen, comprising contacting the specimen with a first reagent comprising one or more monoclonal antibodies to form a conjugate comprising monoclonal antibodies in the first reagent and an antigen in the specimen having epitopes to which said monoclonal antibodies are immunoreactive; contacting the conjugate so formed with a second reagent comprising one or more monoclonal antibodies to form a conjugate comprising the antigen, the monoclonal antibodies from the first reagent and the monoclonal antibodies from the second reagent, wherein one of the first and second reagents comprises two different monoclonal antibodies and the antibodies in the first reagent and the antibodies in the second reagent comprises three different monoclonal antibodies reactive with different epitopes on said antigen; and detecting the conjugate comprising the antigen and the three different monoclonal antibodies.

Abstract: The invention relates to the use of a certain oligosaccharide for preventing clotting in an extracorporeal blood circuit of a patient undergoing extracorporeal blood treatment.

Abstract: The present invention relates to an efficient method of producing monoclonal antibodies against surface antigens of cells and viruses. The method accommodates for antigens which are present in only relatively small amounts, or antigens of which only very small amounts are available or antigens which easily lose their in vivo conformation. Thus the method according to the invention comprises a series of steps, comprising a step in which B-cells from a mammal injected with surface antigen-comprising material are enriched with respect to the relative number of specific B-cells and a step which comprises a small-scale fusion technique.

Abstract: The present invention relates to a concrete composition comprising a hydraulic binder, aggregates, water, silica sol and a superplasticiser being a polycarboxylate. The invention further involves a method for preparation thereof and use of the prepared concrete composition as high fluidity concrete.

Abstract: The invention relates to a novel composition useful as a feed at production of chlorine dioxide, said composition being an aqueous solution comprising from about 1 to about 6.5 moles/liter of alkali metal chlorate, from about 1 to about 7 moles/liter of hydrogen peroxide and at least one of a protective colloid, a radical scavenger or a phosphonic acid based complexing agent, wherein the pH of the aqueous solution is from about 1 to about 4.

Abstract: A novel drug for improving the circulation in the optic nerve head, which comprises as an active ingredient Lomerizine (I): or a pharmaceutically acceptable acid addition salt. The optic nerve head circulation improving drug of this invention can increase the blood flow in the optic nerve head with no or little systemic side effects such as hypotensive activity or heart rate increasing activity and is useful particularly for the treatment of normal tension glaucoma.

Abstract: The present invention relates to a new class of peroxides and to a process for the preparation of these peroxides having the general formula (I), wherein n=1 or 2, R1, R2, R4, R5, and R6 are independently selected from the group comprising hydrogen, C1-C20 alkyl, C3-C20 cycloalkyl, C6-C20 aryl, C7-C20 aralkyl, and C7-C20 alkaryl, or R1 and R2 form a C3-C12 cycloalkyl group, which groups may include linear or branched alkyl moieties; and each of R1, R2, R4, R5, and R6 may optionally be substituted with one or more groups selected from hydroxy, alkoxy, linear or branched alkyl, aryloxy, halogen, ester, carboxy, nitrile, and amido, and R1 and R2 may form a ring, and R3 is independently selected from the group comprising C1-C20, alkyl; C3-C20 cycloalkyl, C6-C20 aryl, C7-C20, aralkyl, and C7-C20 alkaryl, which groups may include linear or branched alkyl moieties; and R3 may optionally be substituted with one or more groups selected from hydroxy, alkoxy, linear or branched alkyl, aryloxy,

Abstract: The invention pertains to a process wherein peroxides are dosed to a polymerization mixture, with essentially all of the organic peroxide that is used in the polymerization process having a half-life from 0.05 hour to 1.0 hour at the polymerization temperature. The dosing of such peroxide allows for accurate control of the polymerization rate, and the process will render a polymer with a low residual peroxide level.

Abstract: The invention relates to an apparatus for applying multi-component coating compositions comprising at least two dosing devices, an air-assisted spray gun, and a controlling device, each dosing device comprising a supply container comprising one component of the multi-component coating composition, a motoring device, and a metering device, the supply container being connected to the metering device, the metering device being connected to the motoring device and to the air-assisted spray gun, the connecting line between at least one metering device and the air-assisted spray gun being fitted with a pressure transducer for measuring a decrease in pressure in the connecting line, the pressure transducer being connected to the controlling device, and the controlling device being connected to the motoring devices, the controlling device capable of comparing the decrease in pressure in the connecting line with a set value, for starting up the motoring devices, and controlling the power of the motoring devices to kee

Abstract: An aqueous silica-based sol comprising a nitrogen-containing organic compound and silica-based particles with a specific surface area of at least 300 square meters per gram of silica. The invention further relates to a process for the production of an aqueous silica-based sol comprising a nitrogen-containing organic compound which comprises incorporating a nitrogen-containing organic compound into a silica-based sol containing silica-based particles with a specific surface area of at least 300 square meters per gram of silica. The invention also relates to the use of an aqueous silica-based sol comprising a nitrogen-containing organic compound and silica-based particles with a specific surface area of at least 300 square meters per gram of silica as a flocculating agent in the production of pulp and paper and in water purification.

Abstract: A process for preparing an esterquat composition comprising (a) reacting a tertiary amine according to formula I: wherein R1 represents a C3-C6 hydrocarbon group, R2 represents a C3-C6 hydrocarbon group, a —R4—OH group or a —CH2[CH(OH)]nCH2OR5 group, if R2 represents a C3-C6 hydrocarbon group, R3 represents a —R4—OH group or a —CH2[CH(OH)]nCH2OR5 group, if R2 represents a —R4—OH group, R3 represents a —R4—OH group or a —CH2[CH(OH)]nCH2OR5 group, if R2 represents a —CH2[CH(OH)]nCH2OR5 group, R3 represents a —CH2[CH(OH)]nCH2OR5 group, R4 represents a C2-C4 hydrocarbon group, n is 1-4, and R5 represents H or a C1-C30 hydrocarbon group, with a C3-C6 hydrocarbyl halide or a di(C3-C6) hydrocarbyl sulfate, followed by (b) reaction with a C8-C30 acid halide, with the proviso that at least one hydroxy group is esterified.

Abstract: A method of reducing the clogging of nozzles and slits and diminishing the formation of deposits in a spin bath system in a process of making viscose filamentary and film materials by using, as a spin bath additive, an amphoteric surfactant having the formula I, and a spin bath system including an amphoteric surfactant having the formula I RNA (CnH2nNA)x−1A  (I) where R represents a hydrogen or an aliphatic group with 1-24 carbon atoms, each A represents a hydrogen, an aliphatic group with 1-24 carbon atoms, or BOOCCmH2m— groups, where m is a number from 1-3, B is hydrogen or a salt forming cation, n is a number from 2-3, x is 1-8, and the number of BOOCCmH2m— groups are from 1 to x+2, with the provision that the total number of carbon atoms in the aliphatic groups is from 8 to 45. The amphoteric surfactant has an excellent anticlogging effect, since it is a good dispersant and prevents or reduces precipitation in the spin bath.

Abstract: Animal feed is disclosed, which contains a polyethylene glycol compound selected from a group consisting of: a) a polyethylene glycol having a molecular weight of 3,000-15,000; b) an ethoxylate of a carboxylic acid having 8-24 carbon atoms; c) an ethoxylate of a mono-, di- or triglyceride containing at least one acyl group having 8-24 carbon atoms; d) an ethoxylate of a mono-, di- or triester of sorbita with a carboxylic ester having 8-24 carbon atoms; and e) an ethoxylate of an alcohol having 8-24 carbon atoms, wherein the ethoxylates b), c), d) and e) have a molecular weight of 15,000 at most and, in an amount of more than 75% by weight, consist of ethyleneoxy units. In addition to the polyethylene glycol compound, the animal feed may also contain 10-70% by weight of cereals, 0-15% by weight of feed fat, 10-50% by weight of protein-containing nutritious substances other than cereals, and 1-10% by weight of vitamins, minerals, enzymes, flavourings, antibiotics, probiotics and other animal feed additives.