Abstract: The present invention relates to a novel bacterial respiratory poultry disease and the identification of the causative agent. A vaccine derived from this agent was effective in preventing the disease in chickens challenged with the virulent field strains.
Type:
Grant
Filed:
November 1, 1996
Date of Patent:
July 20, 1999
Assignee:
Akzo Nobel, N.V.
Inventors:
Paul Karel Storm, Paul Cornelius Maria van Empel
Abstract: An article comprising wood can be preserved by applying to the wood an effective amount for the preservation of the wood of a preservative composition consisting essentially of a polymeric phenol sulfide having a tetra- or higher sulfide bridge therein alkyl phenol sulfide, such as one containing an alkyl group containing from one to about four carbon atoms in the alkyl group contained therein of the following formula, where R is the alkyl group,: ##STR1## where R is alkyl, m is from 1 to 3, n ranges from about 2 to about 10, and x is about 4.
Type:
Grant
Filed:
December 11, 1996
Date of Patent:
July 20, 1999
Assignee:
Akzo Nobel N.V.
Inventors:
Jagadish C. Goswami, Jian-Lin Liu, Andress K. Doyle
Abstract: A process for manufacturing continuous polyester filament yarn for technical applications from a polymer over 90% of the chains of which are composed of-ethylene terephthalate units, via a one-step spinning process, with the undrawn filaments having a crystallinity smaller than 16% and the yarn being wound at a rate larger than 6000 m/min. The yarn obtained in this fashion is particularly suitable for use as reinforcing material in rubber articles, notably as reinforcing material in pneumatic tires for cars. The polyester filament yarn can be used to make cords of uncommonly high dimensional stability and a unique combination of breaking tenacity, shrinkage, and breaking toughness.
Type:
Grant
Filed:
June 12, 1997
Date of Patent:
July 20, 1999
Assignee:
Akzo Nobel N.V.
Inventors:
Hendrikus Wilhelmus Jacobus Hofs, Heinrich Johannes Gustav Kiefer, Henricus Hubertus Wilhelmus Feijen, Lambert van Duren, Christiaan Jurriaan Maria van den Heuvel, Michael Henricus Jacobus van den Tweel
Abstract: The present invention is concerned with European strains of the Porcine Reproductive Respiratory Syndrome (PRRS) virus, having as a unique feature that they are non-infectious to macrophages, and to methods for the production of such strains. The invention also provides vaccines for the protection of pigs against PRRS, based on these strains, as well as methods for the production of such vaccines.
Type:
Grant
Filed:
October 9, 1997
Date of Patent:
July 20, 1999
Assignee:
Akzo Nobel, N.V.
Inventors:
Petrus Alphonsus Maria Van Woensel, Jean Guillaume Joseph Demaret
Abstract: The present invention is in the field of optical recording media, and is directed to an optical recording medium which comprises the following layers;a) a grooved transparent substrate (1), superposed byb) a recording layer comprising a partial mirror (2) of a material having a high complex index of refraction which is not within the pentagon defined by the vertices 7.15 - i3.93, 7.15 - i5.85, 8.96 - 6.28, 9.56 - i5.90, and 8.14 - i3.77 in the n,k plane, superposed by a buffer layer (3) comprising a nonliquid-crystalline high-molecular weight material and optionally a dye, superposed by a thick reflective layer (4), together forming a Fabry-Perot wherein the thickness (d) of the buffer layer within the grooves is set so that the reflection of the medium is in the high reflective state, optionally superposed byc) a protective coating (5).By virtue of the partial mirror, the buffer layer, and the thick reflective layer a Fabry-Perot etalon is created.
Type:
Grant
Filed:
November 26, 1996
Date of Patent:
July 20, 1999
Assignees:
Akzo Nobel N.V., Samsung Electronics Co. Ltd.
Inventors:
Gerrit Cornelis Dubbeldam, Freddy Gerhard Hendrikus van Wijk, Nico Maaskant, Kyung Sun Min, Young Jae Huh, Jong Sung Kim
Abstract: The present invention is concerned with a hog cholera virus vaccine comprising a polypeptide characteristic of hog cholera virus. Vector vaccines capable to express a nucleic acid sequence encoding such a polypeptide also form part of the present invention. Said polypeptide and nucleic acid sequence can also be used for the detection of hog cholera virus infection.
Type:
Grant
Filed:
June 16, 1997
Date of Patent:
July 20, 1999
Assignee:
Akzo Nobel N.V.
Inventors:
Gregor Meyers, Tillmann Rumenapf, Heinz-Jurgen Thiel
Abstract: Disclosed is a pair of primers to amplify a homologous region of the 16S rRNA of Mycobacteria. The primer pair performs better than a number of other primer pairs in a transcription-based amplification system. The amplified RNA can be detected with known probes for Mycobacteria. The primers, methods and kits are especially useful as an aid in the diagnosis of M. tuberculosis.
Abstract: A selective process for the preparation of N-alkyl-beta aminopropionic acids (1) and N-alkyl-beta-iminodipropionic acids (II)RNHC.sub.2 H.sub.4 COOH (I)RNH(C.sub.2 H.sub.4 COOH).sub.2 (II)wherein R is a C.sub.8 to C.sub.24 hydrocarbon, said process comprising reacting an alpha, beta-unsaturated carboxylic acid in aqueous media with the corresponding primary amine of the formula R.sub.1 NH.sub.2 wherein R.sub.1 is a fatty group having 8 to 24 carbon atoms, in the presence of an organic or inorganic base having a pKb of>1<15, whereby the pH of the reaction is maintained in a range of from about 3.5 to about 5.
Abstract: Membranes suitable for use in haemodialysis include a separating layer A with a cut-off between 500 and 5,000,000, a support layer B and a layer C which partly determines the hydraulic permeability. The cut-off and hydraulic permeability can be set independently of one another. The membranes are integral, multi-asymmetric, semi-permeable membranes made from .epsilon.-caprolactam-soluble polymers. The membranes may be in the form of flat, tubular or hollow fiber membranes.
Abstract: A waterproof shoe structure, which includes an outer layer, a lining with a waterproof but water-vapor permeable functional layer, a lining sole, an insole and an outsole. The lining which contains the functional layer has a lower end area which is turned back to the inside and positioned parallel to the outsole. The shoe structure includes: the lower end area of the lining which is turned back lying at the same level as the lining sole, the outer edge of the lining sole at least approximately parallel to and connected to the inner border of the lower end area of the lining which is turned back, the insole bonded from below in a waterproof manner to the functional layer in the lower end area of the lining which is turned back, and the insole waterproofed at least on its surface which faces towards the inside of the shoe structure.
Abstract: An Infectious Bursal Disease Virus of the Delaware Variant E type having the characteristics of being able to grow on both VERO cells and CEF cells, reacting with monoclonal antibody BK9 produced by the cell line having ATCC deposit number HB-10157, not causing bursal atrophy after vaccination and not spreading to birds in physical proximity to immunized birds, said virus being identified as Delaware Variant E 89-03.
Type:
Grant
Filed:
May 28, 1996
Date of Patent:
July 6, 1999
Assignee:
Akzo Nobel N.V.
Inventors:
Piet van der Marel, Martinus A. J. Thijssen, David Snyder, deceased, Dieter Lutticken, Ruud Hein
Abstract: A fabric softener composition with improved fabric softening performance is based upon a mixture of quaternary ammonium fatty acid derivatives one of which is obtained from partially hydrogenated soy triglyceride or fatty acids derived from such triglyceride possessing certain properties of cis/trans isomer ratio and iodine value and the other of which is obtained from tallow acids.
Abstract: The invention relates to an imidazole?1,5a!pyridine derived serine protease inhibitor comprising a unit having general formula (I) ##STR1## wherein R.sub.1 is hydrogen, lower alkyl or an acyl group; R.sub.2 is hydrogen or lower alkyl; R.sub.3 and R.sub.4 are independently hydrogen, lower alkyl or together form .dbd.CH--NR.sub.5 NR.sub.6, R.sub.5 and R.sub.6 being lower alkyl. The compounds are serine protease inhibitors and can be used for the treatment and prophylaxis of thrombosis and thrombin-associated diseases.
Type:
Grant
Filed:
December 2, 1997
Date of Patent:
June 29, 1999
Assignee:
Akzo Nobel, N.V.
Inventors:
Jacobus Albertus Maria Peters, Henricus Carl Joseph Ottenheym, Anton Egbert Peter Adang
Abstract: The invention relates to a process of making pharmaceutical dosage units comprising at least desogestrel or Org 30659 (17.alpha.-17-hydroxy-11-methylene-19-norpregna-4,15-dien-20-yn-3-one), present in an amount of about 0.005 to 1.0 percent by weight of each pharmaceutical dosage unit, characterized in that the steroidal agent, and when required pharmaceutically acceptable excipients, are mixed with water and granulated.
Type:
Grant
Filed:
September 16, 1997
Date of Patent:
June 29, 1999
Assignee:
Akzo Nobel, N.V.
Inventors:
Pieter de Haan, Jocominus Antonius Maria Zwinkels
Abstract: The present invention generally relates to a textile softening composition which comprises, as the softening agent, a quaternary ammonium salt which comprises a mixture of mono-, di- and tri-ester components, wherein the amount of diester quaternary is greater than about 55% by weight, and the amount of triester quaternary is less than about 25% by weight based on the total amount of quaternary ammonium salt. The invention also relates to a process for preparing said softening agent.
Type:
Grant
Filed:
May 3, 1996
Date of Patent:
June 29, 1999
Assignee:
Akzo Nobel NV
Inventors:
Paul Albert Iacobucci, Ralph Franklin, Phuong-Nga Trinh
Abstract: The present invention is concerned with the preparation of improved inactivated vaccines, in particular of inactivated poultry vaccines. The immunogenicity of the inactivated immunogens in such vaccines is enhanced in case live CAV are administered in a combination vaccine with these inactivated immnogens.
Abstract: There is described a novel virus which is the causative agent of fish pancreatic disease, which is a serious disease affecting Atlantic salmon. A method of isolating the virus through co-cultivation of infected tissues following by passage is described and an isolated strain of the virus has been deposited.The use of the virus, or proteins or polypeptide derived therefrom as a vaccine or in diagnosis is described, together with genetically engineered constructs.
Type:
Grant
Filed:
May 8, 1997
Date of Patent:
June 22, 1999
Assignee:
Akzo Nobel, N.V.
Inventors:
Marian F McLoughlin, Robert Thomas Nelson
Abstract: A device and method allow for collection of a blood specimen and for detecting the presence of microorganisms in the blood specimen. The device, a sensor plate under vacuum, provides an environment to culture microbial organism colonies from a blood sample, and a means to facilitate microbial detection and quantification, either manually or with an instrument. The vacuum sensor plate has a microorganism immobilization matrix layer and a sensor layer. Detected microbial colonies are immediately available for further testing. A kit is provided having a needle assembly for direct draw of blood from a patient onto the immobilization layer within the vacuum sensor plate. The sensor plate provides an area for accepting a blood sample, a mechanism to immobilize the blood sample on an interior surface of the plate, nutrients to facilitate growth of microorganisms in the sample, and a sensor layer for allowing the detection and/or enumeration of microorganism colonies within the blood sample.
Abstract: The use of a mixture of at least one alkanolamide of general formula (I), RC(O)NH(A).sub.n H, wherein R is a hydrocarbon group having 7-23 carbon atoms, preferably 11-23 carbon atoms, A is an alkyleneoxy group having 2-4 carbon atoms and n is 2-12, preferably 2-8, and at least one ionic surfactant selected from the group consisting of anionic, cationic, amphoteric and zwitterionic, in a proportion between the alkoxylated alkanolamide and the ionic surfactant from 100:1 to 1:2, preferably in the range from 50:1 to 1:1 for producing a water-base liquid system with reduced flow resistance between the flowing, water-base liquid system and a solid surface.
Type:
Grant
Filed:
March 26, 1997
Date of Patent:
June 15, 1999
Assignee:
Akzo Nobel nv
Inventors:
Martin Hellsten, Ian Harwigsson, Carina Brink
Abstract: Hydrocarbon solutions of a dialkylmagnesium compound having reduced viscosity contain: (a) a hydrocarbon solvent; (b) a dialkylmagnesium compound normally soluble in hydrocarbon solvents; and (c) an effective viscosity reducing amount of a compound selected from the group consisting of a compound having silicon-oxygen bonding, a compound having silicon-nitrogen bonding, and mixtures thereof. Representative viscosity reducing agents include: tetraalkylorthosilicate compounds, such as those of the general formula Si(OR).sub.4, where R is an alkyl group containing from 1 to about 4 carbon atoms, as exemplified by tetraethylorthosilicate; alkylsilazane compounds, including a hexaalkyldisilazane compound containing from 1 to about 4 carbon atoms in the alkyl groups therein as exemplified by hexamethyldisilazane; and silicone oil.
Type:
Grant
Filed:
August 19, 1997
Date of Patent:
June 8, 1999
Assignee:
Akzo Nobel nv
Inventors:
Paul D. Jones, Dennis B. Malpass, Gregory M. Smith