Patents Assigned to Alaunos Therapeutics, Inc.
  • Recombinant Vectors Comprising Polycistronic Expression Cassettes and Methods of Use Thereof
    Publication number: 20240175047
    Abstract: Provided herein are vectors comprising a polycistronic expression casstte comprising a polynucleotide that encodes a TCR alpha chain, a polynucleotide that encodes a TCR beta chain, and a polynucleotide that encodes a cytokine, wherein the polynucleotides are separated by polynucleotide sequences that comprise 2A elements.
    Type: Application
    Filed: February 17, 2022
    Publication date: May 30, 2024
    Applicant: Alaunos Therapeutics, Inc.
    Inventors: Drew Caldwell DENIGER, Lenka Victoria HURTON, Laurence James Neil COOPER, Donghyun JOO, Yaoyao SHI, An LU, Victor CARPIO, Matthew COLLINSON-PAUTZ
  • METHODS OF TREATING GLIOBLASTOMA
    Publication number: 20230399370
    Abstract: The present invention provides methods of treating glioblastoma by administering an adenoviral vector that conditionally expresses IL-12 via gene switch under control of an oral activator ligand.
    Type: Application
    Filed: November 20, 2020
    Publication date: December 14, 2023
    Applicant: Alaunos Therapeutics, Inc.
    Inventors: Laurence James Neil COOPER, Jill Yanetti BUCK, Arnold Bruce GELB, Nathan Aubri DEMARS, Nira HADAR