Abstract: The present invention provides a purified and isolated nucleic acid encoding human prostaglandin transporter (hPGT). The present invention also provides a vector comprising a nucleic acid encoding human prostaglandin transporter (hPGT), a cell stably transformed with this vector, as well as a method for producing a recombinant, human prostaglandin transporter (hPGT). The present invention also provides a purified and isolated human prostaglandin transporter (hPGT), and an antibody immunoreactive with this protein. The present invention further provides a method for evaluating the uptake of a selected prostaglandin by cells expressing nucleic acid encoding human prostaglandin transporter (hPGT).
Type:
Grant
Filed:
September 3, 1996
Date of Patent:
August 11, 1998
Assignee:
Albert Einstin College of Medicine of Yeshiva University, a Division of Yeshiva University