Patents Assigned to Albupharm Heidelberg GmbH & Co. KG
  • Method for producing albumin conjugates containing gyrase inhibitors
    Patent number: 7803791
    Abstract: The present invention is directed to a Gyrase inhibitor-protein conjugate; in particular a Gyrase inhibitor-albumin conjugate. The present invention further provides methods of the treatment of inflammatory conditions and tumors. Methods of making and producing a Gyrase inhibitor-protein conjugate are also disclosed.
    Type: Grant
    Filed: January 20, 2006
    Date of Patent: September 28, 2010
    Assignee: Albupharm Heidelberg GmbH & Co. KG
    Inventors: Hannsjörg Sinn, Marcel Mülbaier
  • Production and use of the methotrexate-albumin conjugate as an immunosuppressive agent in GVHD
    Patent number: 7781406
    Abstract: A method for modulating a transplantation-associated immune response in a subject is disclosed. The method comprises administering to the subject an effective amount of a conjugate comprising a carboxyl group-containing organic compound and albumin, wherein the carboxyl group-containing organic compound is a cytostatic or an immunosuppressant. A method for preparing the conjugate is also disclosed. The method includes activating the carboxyl group-containing organic compound with 1-ethyl-3-(3-dimethylaminopropyl) carbonyldiimide in an organic solvent, and reacting activated carboxyl group-containing organic compound with albumin, wherein the carboxyl group-containing organic compound is a cytostatic or an immunosuppressant.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: August 24, 2010
    Assignee: Albupharm Heidelberg GmbH & Co. KG
    Inventor: Hannsjörg Sinn
  • Method for producing albumin conjugates comprising an X-ray contrast medium as the active substance
    Publication number: 20090047218
    Abstract: The invention concerns X-ray contrast medium-protein conjugates and in particular X-ray contrast medium-albumin conjugates, medicaments comprising X-ray contrast medium-protein conjugates, processes for the production of such conjugates as well as the use thereof.
    Type: Application
    Filed: May 11, 2006
    Publication date: February 19, 2009
    Applicant: Albupharm Heidelberg GmbH & Co. KG
    Inventors: Sinn Hansjorg, Mulbaler Marcel
  • Method For The Production Of Albumen Conjugates With Non-Steroidal Antirheumatic Drugs (Nsar)
    Publication number: 20080306245
    Abstract: The present invention concerns NSAR (non-steroidal antirheumatic agents)-protein conjugates and in particular NSAR-albumin conjugates, processes for their production and their use as pharmaceutical preparations especially for treating inflammations.
    Type: Application
    Filed: November 25, 2005
    Publication date: December 11, 2008
    Applicant: ALBUPHARM HEIDELBERG GMBH & CO. KG
    Inventors: Hannsjorg Sinn, Marcel Mulbaier
  • Method for Producing Albumin Conjugates Containing Gyrase Inhibitors
    Publication number: 20080108708
    Abstract: The present invention concerns gyrase inhibitor-protein conjugates and in particular gyrase inhibitor-albumin conjugates, pharmaceutical preparations comprising gyrase inhibitor-protein conjugates in particular for the treatment and/or prophylaxis of inflammatory processes and/or tumours as well as methods for their production.
    Type: Application
    Filed: January 20, 2006
    Publication date: May 8, 2008
    Applicant: ALBUPHARM HEIDELBERG GMBH & CO. KG
    Inventors: Hannsjorg Sinn, Marcel Mulbaier
  • Method for Producing Albumin-Corticoid Conjugates
    Publication number: 20080051376
    Abstract: The invention relates to corticoid/transport protein conjugates, methods for the production thereof, and the use of the same in medicine, especially for the treatment of tumours and inflammatory processes, and for immunosuppression.
    Type: Application
    Filed: July 14, 2005
    Publication date: February 28, 2008
    Applicant: Albupharm Heidelberg GMBH & Co. KG
    Inventor: Hannsjorg Sinn