Abstract: The disclosure herein provides methods, systems, and devices for a sterile ophthalmic surgical drape system that can provide a sterile operating field for use by a doctor, surgeon, nurse, and the like during ophthalmic medical procedures. The sterile field created by the drape system can allow a doctor, surgeon, nurse and the like to perform a medical procedure, such as ophthalmic surgery, outside of an operating room and in locations such as a doctor's office or a military operating room war setting. The sterile ophthalmic surgical drape system can comprise a drape, a frame apparatus, a hole of sufficient size for a microscope, a fan, a filter, air directors, and slits. The drape system can comprise a collapsible frame apparatus. The drape system may be configured to be used in conjunction with a surgical tray that houses pre-sterilized tools for use in a medical procedure.

Abstract: The disclosure herein provides ophthalmic surgical systems, methods, and devices. In one embodiment, a handheld medical instrument for surgical procedures comprises a body having an exterior surface shaped to be held and manipulated by a human hand; a surgical tool extending from a distal end of the body; and a pressure-sensitive button for controlling operation of the surgical tool, the pressure-sensitive button comprising an actuation surface positioned adjacent the exterior surface of the body, the pressure-sensitive button further comprising a pressure detection device, the pressure detection device configured to enable output of a signal for controlling a function of the surgical tool, the signal being proportional to a position of the actuation surface.

Abstract: The disclosure herein provides methods, systems, and devices for a sterile ophthalmic surgical drape system that can provide a sterile operating field for use by a doctor, surgeon, nurse, and the like during ophthalmic medical procedures. The sterile field created by the drape system can allow a doctor, surgeon, nurse and the like to perform a medical procedure, such as ophthalmic surgery, outside of an operating room and in locations such as a doctor's office or a military operating room war setting. The sterile ophthalmic surgical drape system can comprise a drape, a frame apparatus, a hole of sufficient size for a microscope, a fan, a filter, air directors, and slits. The drape system can comprise a collapsible frame apparatus. The drape system may be configured to be used in conjunction with a surgical tray that houses pre-sterilized tools for use in a medical procedure.

Abstract: An intraocular lens inserter can include an energy storage portion, an actuator portion, and a lens support portion. The energy storage portion can include a compressible energy storage device, such as a compressible fluid, springs, and other devices. The inserter can include an actuator portion operating with a substantially incompressible fluid, such as liquids or other noncompressible fluids. The actuator can be configured to provide an operator with control over the release of energy from the energy storage portion so as to move a plunger for the discharge of a lens from an intraocular lens cartridge.

Abstract: A gas mixture apparatus includes a measurement control system, an activation system, a pressurized chamber with one or more gases, and a mixing chamber. The apparatus can also include additional pressure regulation control systems. The gas mixture apparatus can be used to introduce and automatically perform the steps to achieve a desired concentration of the one or more gases contained in the pressurized chamber. The gas mixture apparatus can include the pressurized chamber within the apparatus itself such that no external devices are necessary for introducing the one or more gases into the mixing chamber.

Abstract: Embodiments of the invention refer to a system for registering and tracking the position of a person's eye, in particular for refractive ophthalmic surgery. According to embodiments, the system is structured such that eye images containing at least the iris and the pupil of the eye are made at a first wavelength of light and that eye images containing scleral blood vessels are made at a different second wavelength of light. The invention furthermore refers to a corresponding method for registering and tracking the position of a person's eye.

Abstract: An intraocular lens inserter can include an energy storage portion, an actuator portion, and a lens support portion. The energy storage portion can include a compressible energy storage device, such as a compressible fluid, springs, and other devices. The inserter can include an actuator portion operating with a substantially incompressible fluid, such as liquids or other noncompressible fluids. The actuator can be configured to provide an operator with control over the release of energy from the energy storage portion so as to move a plunger for the discharge of a lens from an intraocular lens cartridge.

Abstract: An intraocular lens inserter can include an energy storage portion, an actuator portion that provides temperature compensation, and a lens support portion. The energy storage portion can include a compressible energy storage device, such as a compressible fluid, springs, and other devices. The inserter can include an actuator portion operating with a substantially incompressible fluid. The actuator can be configured to provide an operator with control over the release of pressurized fluid so as to move a plunger for the discharge of a lens from an intraocular lens cartridge, discharge of the lens being limited based at least in part on pressure feedback from the pressurized fluid due temperature increases.

Abstract: An intraocular lens inserter can include a drive device with controllable advance motion. The drive device may include an actuator device and an energy device. The actuator device may include a piston rod that uses the advance motion to push an intraocular lens from a cartridge for insertion into an eye of an animal. The energy device may act upon the actuator device to generate the advance motion. The actuator device may include a dampening medium to control the advance motion, such as by controllably dampening the advance motion.

Abstract: The disclosure herein provides ophthalmic surgical systems, methods, and devices. In one embodiment, a surgical apparatus for use by a surgeon during a surgical procedure comprises one or more sealed sterilized surgical packs configured to be disposed of after a single or a limited number of surgical procedures, the one or more sealed sterilized surgical packs comprising: a sterile surgical instrument; and a sterile surgical tray comprising a top surface configured to be part of a sterile field of the surgical procedure, the top surface comprising a receiving structure for positioning therein of the sterile surgical instrument, the sterile surgical tray further comprising walls that define a recess sized and configured to receive a reusable non-sterile module, the recess configured to encapsulate the reusable non-sterile module to isolate the reusable non-sterile module from the sterile field of the surgical procedure.

Abstract: An intraocular lens inserter can include an energy storage portion, an actuator portion, and a lens support portion. The energy storage portion can include a compressible energy storage device, such as a compressible fluid, springs, and other devices. The inserter can include an actuator portion operating with a substantially incompressible fluid, such as liquids or other noncompressible fluids. The actuator can be configured to provide an operator with control over the release of energy from the energy storage portion so as to move a plunger for the discharge of a lens from an intraocular lens cartridge.

Abstract: Aqueous suspension formulations containing dexamethasone and ciprofloxacin are disclosed for the treatment of middle ear infections in human patients having an open tympanic membrane.

Abstract: Aqueous suspension formulations containing dexamethasone and ciprofloxacin are disclosed for the treatment of middle ear infections in human patients having an open tympanic membrane.

Abstract: Aqueous suspension formulations containing dexamethasone and ciprofloxacin are disclosed for the treatment of middle ear infections in human patients having an open tympanic membrane.

Abstract: A method for performing multi-level eye registration comprising: obtaining a first initial reference eye image by a first diagnostic device and defining a reference coordinate system; obtaining a second eye image by a surgery device, said second eye image being obtained in a pre-surgery phase before the surgery has started; performing a first registration between said first eye image and said second eye image to obtain a first registration result; obtaining a third eye image by said surgery device, said third eye image being obtained after surgery has started; performing a second registration between said second eye image and said third eye image to obtain a second registration result; combining said first and second registration results to obtain a combined registration result to thereby obtain a registration between said initial reference eye image obtained by said diagnostic device and said third eye image obtained by said surgery device after surgery has started.

Abstract: A method for performing multi-level eye registration comprising: obtaining a first initial reference eye image by a first diagnostic device and defining a reference coordinate system; obtaining a second eye image by a surgery device, said second eye image being obtained in a pre-surgery phase before the surgery has started; performing a first registration between said first eye image and said second eye image to obtain a first registration result; obtaining a third eye image by said surgery device, said third eye image being obtained after surgery has started; performing a second registration between said second eye image and said third eye image to obtain a second registration result; combining said first and second registration results to obtain a combined registration result to thereby obtain a registration between said initial reference eye image obtained by said diagnostic device and said third eye image obtained by said surgery device after surgery has started.

Abstract: Aqueous suspension formulations containing dexamethasone and ciprofloxacin are disclosed for the treatment of middle ear infections in human patients having an open tympanic membrane.

Abstract: An apparatus for monitoring one or more parameters of the eye of a patient over multiple sessions which are temporally spaced apart and between which the eye of the patient can have moved, said apparatus comprising: a camera for taking one or more images of the eye; an illumination unit for illuminating the eye by a ring-shaped light pattern to generate corneal reflections, said illumination unit being preferably located such that the center of the ring is coaxial with the optical axis of the camera; a module for determining during a first session the location of the corneal reflections in the image of the eye; a module for determining during said first session based on said determined location of the corneal reflections, at least one further parameter of the eye and its coordinates in a first coordinate system based on a geometrical model representing the eye as a spherical eyeball having a spherically shaped cornea mounted thereon; a module for determining during a second session temporally spaced apart fro

Abstract: Image processing for computer-aided eye-surgery includes acquiring a reference image of the eye and enriching said reference image by inserting additional context information which are helpful for a surgeon when performing the eye surgery. The reference image is registered with a real time image of the eye. The context information is overlayed over the real time image of the eye based on a tracking of the eye movement such that the context information is displayed at the same position despite a movement of the eye.

Abstract: Ophthalmic, otic and nasal compositions containing a new class of antibiotics (e.g., moxifloxacin) are disclosed. The compositions preferably also contain one or more anti-inflammatory agents. The compositions may be utilized to treat ophthalmic, otic and nasal conditions by topically applying the compositions to the affected tissues.