Abstract: 2-Trisubstituted Phenylimino-imidazolines also known as 2-(trisubstituted anilino)-1,3 diazacyclopentene-(2) compounds and their use for lowering intraocular pressure are disclosed.

Abstract: An ophthalmic irrigating solution useful for irrigating the human eye contains sodium, potassium, magnesium, calcium, chloride, and bicarbonate ions as well as dextrose and glutathione in proportions consistent with the osmotic stability and continued metabolism of the endothelial cells. The irrigating solution is prepared by mixing a first basic solution which provides the bicarbonate and a second acidic solution which provides the calcium, magnesium, dextrose and glutathione. The first and second solutions may be stored as stable, sterile solutions for extended periods of time and mixed within 24 hours of use.

Abstract: Tetracyclic spiro-hydantoin derivatives useful in the treatment of complications arising from diabetes mellitus.

Abstract: Inhibition of aldose reductase activity with tetracyclic spiro-hydantoins.

Abstract: This invention relates to polymeric alcohols and polymeric ethers including poly(ethylene glycol), polyethylene oxide and polyethylene glycol methyl ether as prophylactic agents against soilant deposits on contact lenses.

Abstract: A process for rendering contact lenses made of a polymer or mixture of polymers hydrophilic or increasing their hydrophilic nature comprising generating a beam of positive ions which are essentially of equal kinetic energy, bombarding in an essentially uniform manner the surface of each lens by means of this beam and thereafter hydrating each contact lens; the positive ion beam is obtained by subjecting a gas from the group consisting of nitrogen, oxygen or compounds of these to an electric field produced between a cathode and an anode and in causing part of the accelerated positive ions to pass through the cathode.

Abstract: The present invention is directed to an aqueous dispersion of an ophthalmic drug and a high molecular weight polymer which forms a highly viscous gel and can be used to prolong the duration of activity of the ophthalmic drug when the gel is applied into the conjunctival sac of the eye. The ophthalmic drug-containing gel composition has prolonged retention time in the eye and remains in contact with the surface of the eye for an extended period of time.

Abstract: This invention relates to the quaternary ammonium salt, .alpha.-4-[-tris (2-hydroxyethyl) ammonium chloride-2-butenyl] poly[1-dimethyl ammonium chloride-2-butenyl]-w-tris (2-hydroxyethyl) ammonium chloride, providing aqueous disinfecting solutions for contact lenses as well as a preservative for ocular solutions including contact lens treating solutions.

Abstract: The invention relates to a fabrication method for molding a contact lens with the required optical qualities.This method consists in designing a mold (1, 2) of high thermal inertia, which is transparent to, or little absorbing the electromagnetic microwave frequencies between 10.sup.6 Hz and 10.sup.11 Hz, in developing a base composition from polymerizing double-bond monomers which are absorbing with respect to the above microwaves, and in ensuring the polymerization of the composition within the closed mold by irradiation with the above cited electromagnetic waves at a power density suited to keep the temperature at the mold level approximately below 40.degree. C.

Abstract: The invention relates to a fabrication process for molding a contact lens evincing the required optical properties.This method consists in designing a mold (1,2) with a high thermal inertia, transparent to, or little absorbing electromagnetic waves with wavelengths between 1 micron and 10.sup.-6 microns, in developing a base composition from polymerizing double-bond monomers which are absorbing with respect to these waves and in securing the polymerization of the composition inside the closed mold by irradiating with the above-cited electromagnetic waves at a power density such as to keep the temperature approximately less than 40.degree. C. at the mold level.

Abstract: A contact lens bathing case, in which a pair of contact lenses is sealed with a cleaning and disinfectant solution, and a heating unit, for receiving and heating the filled case therein, cooperate to eliminate leakage problems, i.e. loss of solution, associated with improperly closed contact lens cases. The heating case includes a heating element and a movable lens case holder which is movable from an open position remote from the heating element to a closed position adjacent to the heating element whereat the solution and lenses may be heated. Closure prevention means prevent the holder which has received an improperly closed case from being moved to the closed position.

Abstract: The present invention is directed to an aqueous dispersion of an ophthalmic drug and a high molecular weight polymer which forms a highly viscous gel and can be used to prolong the duration of activity of the ophthalmic drug when the gel is applied into the conjunctival sac of the eye. The ophthalmic drug-containing gel composition has prolonged retention time in the eye and remains in contact with the surface of the eye for an extended period of time.

Abstract: Iodinated thiolcarbonates and a method for using the same as radiographic contrast agents in connection with such X-ray techniques as myleography, lymphography, hysterosalpingography, bronchography and sialography. The general formula of such iodonated thiolcarbonate compounds may be characterized as ##STR1## wherein R represents an iodinated phenyl linked to the sulfur through a lower alkylene group consisting of a straight or branched chain having from 1 to 5 carbon atoms and R.sub.1 is a lower alkyl group consisting of a straight or branched chain having from 1 to 10 carbon atoms.

Abstract: An electrical connector of the type known in the television industry as A.C. interlock plug, comprises a dielectric body having opposite faces and an opening extending therethrough and through both of the opposite faces. A contact member having a pin body and a solder lug extending from one end of the body, has the solder lug projecting through the opening, a shoulder on the pin body engaging the dielectric body as a stop and spur means on the solder lug retainingly engaging with the dielectric body to prevent withdrawal of the contact member.The contact member may be formed up from sheet metal into a tubular pin body and a transversely arcuately reinforced solder lug on which the spur means comprise one or more shear formed pointed projections along the edges of the solder lug.

Abstract: A syringe device is disclosed which employs an operator cooperable with the plunger of a syringe cartridge to facilitate discharge of fluid from the syringe cartridge. Various embodiments of the operator each include a sleeve portion which progressively telescopes the barrel of the syringe cartridge to prevent its fracture and lend stability to the assembly during operation. The operators are cooperable with the syringe cartridge to selectively discharge one or more predetermined dosages from the syringe.

Abstract: A syringe device is disclosed which employs an operator cooperable with the plunger of a syringe cartridge to facilitate discharge of fluid from the syringe cartridge. Various embodiments of the operator each include a sleeve portion which progressively telescopes the barrel of the syringe cartridge to prevent its fracture and lend stability to the assembly during operation. The operators are cooperable with the syringe cartridge to selectively discharge one or more predetermined dosages from the syringe.

Abstract: A socket body has increased retention means for push-on retaining engagement with a tube base supplemental to the usual frictional retaining engagement between mating terminals of the socket and tube base. In one form the increased retention means comprises a compressible split key. In another form the increased retention means comprises gripping fingers.

Abstract: Ophthalmic solution suitable as an artificial tear material of low viscosity containing a polysaccharide and benzalkonium chloride.

Abstract: A method of making an electrical connector especially suitable for coupling an antenna leadin with a printed circuit board in a receiver chassis comprising forming up a tubular sheet metal body from an originally flat blank into tubular form with confronting edges along a longitudinal joint, providing opposite ends of the body with means for mounting it in functioning position, assembling within the body a member such as a dielectric support carrying an electrical contact in electrically contacting relation at a location within the body spaced from one end of the body which provides an opening into a plug-receiving socket between said one end and said support and mechanically interlocking the dielectric support and the body to retain the body against spreading open at the joint in the vicinity of the support. More specifically, interlocking lug-means are driven from the body into a recess in the support to effect the interlocking relationship.

Abstract: A simple three-piece binding post is provided having a hollow generally tubular housing for mounting on a support such as a binding post panel, a binding plunger reciprocable within the housing, and a spring for engagement with the support and for thrusting the plunger to bind a lead terminal inserted into normally offset but alignable lead-receiving openings in the housing and plunger.