Abstract: An ophthalmic device includes an optic having an optic axis and a closed-loop haptic structure coupled with the optic. The closed loop haptic structure includes a first hinge having a first section, a second section, and a connecting section extending between the first section and the second section. The first section has a first component extending in a first angular direction and a second component extending in a second angular direction that is opposite to the first angular direction. The closed loop haptic structure further includes a second hinge including a radial section and an axial section extending from the axial section in the first angular direction, the radial section having a cross-sectional area greater than a maximum cross-sectional area of the first hinge.

Abstract: An ocular implant delivery system is provided with a number of features. In some embodiments, the delivery system comprises a rotation mechanism configured to rotate and orient a cannula of the system, and an advancement mechanism configured to advance and retract an ocular implant through the delivery system and into an eye of a patient. In some embodiments, the cannula is sized and configured to be inserted into Schlemm's canal of the eye. The ocular implant is configured to maintain its orientation within the delivery system as the cannula is rotated. In some embodiments, the ocular implant automatically disengages the delivery system when it is advanced beyond a distal tip of the delivery system. Methods of implanting an ocular implant are also provided.

Abstract: Disclosed embodiments provide systems and methods for preventing unintentional laser emission via an integrated foot controller having an electronic shroud that is implemented using electronics and software. The risk of unintentional laser emission is reduced by permitting laser emission via the pedal of the foot controller only at defined stages of surgical procedures, and by requiring that the user initiate control of laser emission by actuating existing switches on the foot controller in a specified sequence, such as a passcode unique to a particular user. Additionally, disclosed embodiments include one more proximity sensors useful to detect data indicative of the presence of the user's foot on the foot controller. Such data may be useful in determining whether the system should remain in a ready state for laser emission or whether the system should be taken out of ready state to reduce the risk of unintentional laser emission when the user's foot is not present.

Abstract: Disclosed are apparatus, systems, and methods for objectively assessing accommodation in an eye. For example, a method for objectively assessing accommodation can comprise displaying, at a far display, a stimulus target for a first duration and displaying, at a near display, the stimulus target for a second duration. The stimulus target displayed at the near display can be projected onto a first beam splitter positioned at an oblique angle with respect to the near display. The stimulus target displayed on the far display can be axially aligned with the stimulus target projected onto the first beam splitter. The method can also comprise obtaining, at a controller, measurements concerning refractive states of the eye during the first duration and the second duration from a refractor device in communication with the controller and determining, using the controller, an accommodative response of the eye based in part on the respective refractive states.

Abstract: The invention is generally related to a method for producing coated silicone hydrogel contact lenses each of which has a hydrogel coating thereon and a relative high resistance to uptakes of polycationic antimicrobials as characterized by having a polyquaternium-1-uptake of less than 0.40 micrograms/lens. The hydrogel coating is formed by covalently attached a hydrophilic polymeric material onto a base coating of a polyanionic polymer on a SiHy contact lens. In this method, lower polyquaternium-1-uptake is achieved by using a rinse solution with a higher pH and/or a higher ionic strength (higher salt concentration) for rinsing a treated silicone hydrogel contact lens with a base coating of polyanionic polymer.

Abstract: A stereoscopic imaging platform includes a stereoscopic camera configured to record left and right images of a target site. A robotic arm is operatively connected to the stereoscopic camera, the robotic arm being adapted to selectively move the stereoscopic camera relative to the target. The stereoscopic camera includes a lens assembly having at least one lens and defining a working distance. The lens assembly has at least one focus motor adapted to move the at least one lens to selectively vary the working distance. A controller is adapted to selectively execute one or more automatic focusing modes for the stereoscopic camera. The controller has a processor and tangible, non-transitory memory on which instructions are recorded. The automatic focusing modes include a target locking mode. The target locking mode is adapted to maintain a focus of the at least one stereoscopic image while the robotic arm is moving the stereoscopic camera.

Abstract: A stereoscopic imaging platform includes a stereoscopic camera configured to record left and right images of a target site. A robotic arm is operatively connected to the stereoscopic camera, the robotic arm being adapted to selectively move the stereoscopic camera relative to the target. The stereoscopic camera includes a lens assembly having at least one lens and defining a working distance. The lens assembly has at least one focus motor adapted to move the at least one lens to selectively vary the working distance. A controller is adapted to selectively execute one or more automatic focusing modes for the stereoscopic camera. The automatic focusing modes include a continuous autofocus mode adapted to maintain a focus of the at least one stereoscopic image while the robotic arm is moving the stereoscopic camera and the target site is moving along at least an axial direction.

Abstract: A stereoscopic imaging platform includes a stereoscopic camera configured to record left and right images of a target site. A robotic arm is operatively connected to the stereoscopic camera, the robotic arm being adapted to selectively move the stereoscopic camera relative to the target. The stereoscopic camera includes a lens assembly having at least one lens and defining a working distance. The lens assembly has at least one focus motor adapted to move the at least one lens to selectively vary the working distance. A controller is adapted to selectively execute one or more automatic focusing modes for the stereoscopic camera. The controller has a processor and tangible, non-transitory memory on which instructions are recorded. The automatic focusing modes include a disparity mode and/or a sharpness control mode which are adapted to at least partially rely on disparity feedback to change the working distance in order to achieve focus.

Abstract: The invention provides a hydrophilized polydiorganosiloxane vinylic crosslinker which comprises (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and hydrophilized siloxane units each having one methyl substituent and one monovalent C4-C40 organic radical substituent having two to six hydroxyl groups, wherein the molar ratio of the hydrophilized siloxane units to the dimethylsiloxane units is from about 0.035 to about 0.15, and (2) two terminal (meth)acryloyl groups. The hydrophilized polydiorganosiloxane vinylic crosslinker has a number average molecular weight of from about 3000 Daltons to about 80,000 Daltons. The present invention is also related to a silicone hydrogel contact lens, which comprises repeating units derived from a hydrophilized polydiorganosiloxane vinylic crosslinker of the invention.

Abstract: Systems, circuits, and methods to mitigate effects of short-term power losses in medical systems are provided. An exemplary surgical system includes a fluidics subsystem, a surgical instrument subsystem that couples to a surgical instrument and a power supply subsystem coupled to the surgical instrument subsystem. The power supply subsystem includes a main power supply connectable to AC mains to generate a voltage, a power bus connected to the main power supply, an alternate power supply, and a circuit that monitors the voltage on the power bus for powering the surgical instrument subsystem. The circuit automatically connects the power bus to the alternate power supply when the voltage drops below a reference voltage due to a power loss from the main power supply.

Abstract: A method of calibrating a robotic imaging apparatus includes providing the robotic imaging apparatus, calibrating a stereoscopic camera portion of the apparatus to robot space, and registering the robot space to a patient space. An embodiment of the apparatus includes a base section defining the robot space, a robotic arm including a first end connected to the base section, a second end including a coupling interface, and a plurality of joints and links connecting the first end to the second end, each joint including a motor configured to rotate the joint around an axis and a joint sensor configured to transmit a position of the respective joint, a stereoscopic camera connected at the coupling interface, and a sensor positioned at the coupling interface and configured to detect force imparted on the stereoscopic camera by an operator and to transmit output data indicative of the detected force.

Abstract: A system, method, and apparatus for displaying a fused reconstructed image with a multidimensional image are disclosed. An example imaging system receives a selection corresponding to a portion of a displayed multidimensional visualization of a surgical site. At the selected portion of the multidimensional visualization, the imaging system displays a portion of a three-dimensional image which corresponds to the selected multidimensional visualization such that the displayed portion of the at least one of the three-dimensional image or model is fused with the displayed multidimensional visualization.

Abstract: The invention provides a method for determining whether a coated contact lens is completely covered by a covalently bonded coating, comprising the steps of (1) providing a coated polyvinylalcohol-based hydrogel contact lens wherein the polyvinylalcohol-based hydrogel lens body is composed of a polymer comprising at least 50% by mole of repeating units of vinyl alcohol, comprising a lubricious coating covalently attached to the lens body, (2) contacting the coated polyvinylalcohol-based hydrogel contact lens with an aqueous solution of a hydrophilic marker polymer for obtaining a treated contact lens, the hydrophilic marker polymer having reactive groups of in which R1 is methyl or ethyl and R2 is hydrogen or a C1-C4 alkyl and a dye tag moiety, at a pH of 4.

Abstract: Modular IOL removal systems and methods that cut an optic portion of an intraocular in a single motion such to facilitate removal of the optic portion from an eye through an incision, for example a corneal incision, without increasing the size of the corneal incision. Various cutting tools having one or more blades may be utilized. The cut intraocular lens may have one continuous cut or be cut into multiple smaller pieces. The single cutting step may apply balanced forces and torque to avoid damaging the surrounding eye anatomy, reducing the risk of trauma.

Abstract: The invention is generally related to a process for producing a relatively high molecular weight poly(methacrylic acid) (“PMAA”) in a water-based system. The process of the invention comprises polymerization of from about 1% to about 20% by weight of methacrylic acid in water or a water-based system in the presence of thiol compound and an azo radical initiator under controlled reaction and process conditions. A process of the invention can be easily scaled up into the pilot scale for producing large quantities of high molecular weight PMAAs. The invention is also related to high molecular weight poly(methacrylic acid)s obtained according to a process of the invention.

Abstract: Certain aspects of the present disclosure provide to angle adjustment systems using one or more spring arrangements. In certain aspects, an angle adjustment system comprises a component and a first spring arrangement coupled to the component, wherein the first spring arrangement comprises at least three spring elements. Further, the first spring arrangement is configured to allow the component to rotate around a first axis of rotation and prevent a first translational movement of the component with respect to the first axis of rotation.

Abstract: An intraocular lens system may include a base that may include an annular body, an opening extending through the annular body in an axial direction of the annular body, and a recess extending circumferentially about the opening. The system also may include a lens that may be insertable into and removable from the recess. The lens may include a central optic, a first tab protruding radially away from the central optic, and a second tab protruding radially away from the central optic. The second tab may be more resistant to compression in a radial direction than the first tab. The first tab may include a first arm protruding radially away from the central optic, a second arm protruding radially away from the central optic and extending away from the first arm, and a third arm extending from the first arm to the second arm. Movement of one or more of the first, second, and third arms may result in deformation of the first tab.

Abstract: Certain embodiments provide a cover mounted on top of a manifold, the cover comprising an exhaust opening and an inner surface forming a space between the inner surface of the cover and an outer surface of the manifold, wherein the space is configured to receive pressurized gas at an inlet positioned on a first side of a valve. The valve is coupled to the outer surface of the manifold and positioned within the space. The exhaust opening is positioned on a second side of the valve opposite the first side of the valve such that pressurized gas circulates from the inlet around the valve and exits through the exhaust opening.

Abstract: An IOL injector having an automatic plunger advancement driver is described. In addition, an IOL injector having a spring-assisted driving mechanism and a spring damping mechanism is described.

Abstract: An intraocular lens (IOL) injectors and associated methods are described. The IOL injectors may include a collapsible portion configured to reduce the length of the IOL injector when the collapsible portion is altered from an uncollapsed configuration to a collapsed configuration. In some instances, an IOL may be advanced from a storage location to a dwell location when the collapsible portion is altered from the uncollapsed configuration to the collapsed configuration. The IOL injectors may also include a combination push and screw drive.